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From a natural product lead to the identification of potent and selective benzofuran-3-yl-(indol-3-yl)maleimides as glycogen synthase kinase 3beta inhibitors that suppress proliferation and survival of pancreatic cancer cells.
Gaisina IN, Gallier F, Ougolkov AV, Kim KH, Kurome T, Guo S, Holzle D, Luchini DN, Blond SY, Billadeau DD, Kozikowski AP. Gaisina IN, et al. Among authors: gallier f. J Med Chem. 2009 Apr 9;52(7):1853-63. doi: 10.1021/jm801317h. J Med Chem. 2009. PMID: 19338355 Free PMC article.
Developments in the chemistry and biology of 1,2,3-triazolyl-C-nucleosides.
Nascimento SMRD, Ferry A, Gallier F, Lubin-Germain N, Uziel J, Gonzales S, Miranda LSME. Nascimento SMRD, et al. Among authors: gallier f. Arch Pharm (Weinheim). 2024 Mar;357(3):e2300580. doi: 10.1002/ardp.202300580. Epub 2023 Dec 27. Arch Pharm (Weinheim). 2024. PMID: 38150650 Review.
Studies on the synthesis of 1'-CN-triazolyl-C-ribosides.
Bozinovic N, Aguiar VM, Ferry A, Gallier F, Lubin-Germain N, Uziel J, Miranda LSME. Bozinovic N, et al. Among authors: gallier f. Org Biomol Chem. 2022 Sep 21;20(36):7261-7269. doi: 10.1039/d2ob01403c. Org Biomol Chem. 2022. PMID: 36069280
Anti-HCV and Zika activities of ribavirin C-nucleosides analogues.
Gonzalez S, Brzuska G, Ouarti A, Gallier F, Solarte C, Ferry A, Uziel J, Krol E, Lubin-Germain N. Gonzalez S, et al. Among authors: gallier f. Bioorg Med Chem. 2022 Aug 15;68:116858. doi: 10.1016/j.bmc.2022.116858. Epub 2022 May 29. Bioorg Med Chem. 2022. PMID: 35661850
18 results