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The secret ally: immunostimulation by anticancer drugs.
Galluzzi L, Senovilla L, Zitvogel L, Kroemer G. Galluzzi L, et al. Nat Rev Drug Discov. 2012 Feb 3;11(3):215-33. doi: 10.1038/nrd3626. Nat Rev Drug Discov. 2012. PMID: 22301798 Review.
Mitochondria as therapeutic targets for cancer chemotherapy.
Galluzzi L, Larochette N, Zamzami N, Kroemer G. Galluzzi L, et al. Oncogene. 2006 Aug 7;25(34):4812-30. doi: 10.1038/sj.onc.1209598. Oncogene. 2006. PMID: 16892093 Review.
Mitochondrial membrane permeabilization in cell death.
Kroemer G, Galluzzi L, Brenner C. Kroemer G, et al. Among authors: galluzzi l. Physiol Rev. 2007 Jan;87(1):99-163. doi: 10.1152/physrev.00013.2006. Physiol Rev. 2007. PMID: 17237344 Review.
A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib.
de La Motte Rouge T, Galluzzi L, Olaussen KA, Zermati Y, Tasdemir E, Robert T, Ripoche H, Lazar V, Dessen P, Harper F, Pierron G, Pinna G, Araujo N, Harel-Belan A, Armand JP, Wong TW, Soria JC, Kroemer G. de La Motte Rouge T, et al. Among authors: galluzzi l. Cancer Res. 2007 Jul 1;67(13):6253-62. doi: 10.1158/0008-5472.CAN-07-0538. Cancer Res. 2007. PMID: 17616683
Hierarchical involvement of Bak, VDAC1 and Bax in cisplatin-induced cell death.
Tajeddine N, Galluzzi L, Kepp O, Hangen E, Morselli E, Senovilla L, Araujo N, Pinna G, Larochette N, Zamzami N, Modjtahedi N, Harel-Bellan A, Kroemer G. Tajeddine N, et al. Among authors: galluzzi l. Oncogene. 2008 Jul 10;27(30):4221-32. doi: 10.1038/onc.2008.63. Epub 2008 Mar 24. Oncogene. 2008. PMID: 18362892
In VDAC1-depleted cells, the failure of CDDP to activate Bax could be reversed by means of the Bcl-2/Bcl-X(L) antagonist ABT-737, which concomitantly restored CDDP cytotoxicity. ...
In VDAC1-depleted cells, the failure of CDDP to activate Bax could be reversed by means of the Bcl-2/Bcl-X(L) antagonist ABT-737, whi …
Regulation of autophagy by cytoplasmic p53.
Tasdemir E, Maiuri MC, Galluzzi L, Vitale I, Djavaheri-Mergny M, D'Amelio M, Criollo A, Morselli E, Zhu C, Harper F, Nannmark U, Samara C, Pinton P, Vicencio JM, Carnuccio R, Moll UM, Madeo F, Paterlini-Brechot P, Rizzuto R, Szabadkai G, Pierron G, Blomgren K, Tavernarakis N, Codogno P, Cecconi F, Kroemer G. Tasdemir E, et al. Among authors: galluzzi l. Nat Cell Biol. 2008 Jun;10(6):676-87. doi: 10.1038/ncb1730. Epub 2008 May 4. Nat Cell Biol. 2008. PMID: 18454141 Free PMC article.
Disruption of the hexokinase-VDAC complex for tumor therapy.
Galluzzi L, Kepp O, Tajeddine N, Kroemer G. Galluzzi L, et al. Oncogene. 2008 Aug 7;27(34):4633-5. doi: 10.1038/onc.2008.114. Epub 2008 May 12. Oncogene. 2008. PMID: 18469866
Erlotinib and gefitinib for the treatment of myelodysplastic syndrome and acute myeloid leukemia: a preclinical comparison.
Boehrer S, Adès L, Galluzzi L, Tajeddine N, Tailler M, Gardin C, de Botton S, Fenaux P, Kroemer G. Boehrer S, et al. Among authors: galluzzi l. Biochem Pharmacol. 2008 Dec 1;76(11):1417-25. doi: 10.1016/j.bcp.2008.05.024. Epub 2008 Jul 9. Biochem Pharmacol. 2008. PMID: 18617157
Targeting p53 to mitochondria for cancer therapy.
Galluzzi L, Morselli E, Kepp O, Tajeddine N, Kroemer G. Galluzzi L, et al. Cell Cycle. 2008 Jul 1;7(13):1949-55. doi: 10.4161/cc.7.13.6222. Cell Cycle. 2008. PMID: 18642442 Review.
Viral subversion of immunogenic cell death.
Kepp O, Senovilla L, Galluzzi L, Panaretakis T, Tesniere A, Schlemmer F, Madeo F, Zitvogel L, Kroemer G. Kepp O, et al. Among authors: galluzzi l. Cell Cycle. 2009 Mar 15;8(6):860-9. doi: 10.4161/cc.8.6.7939. Epub 2009 Mar 26. Cell Cycle. 2009. PMID: 19221507 Review.
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