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Mitochondria as therapeutic targets for cancer chemotherapy.
Galluzzi L, Larochette N, Zamzami N, Kroemer G. Galluzzi L, et al. Oncogene. 2006 Aug 7;25(34):4812-30. doi: 10.1038/sj.onc.1209598. Oncogene. 2006. PMID: 16892093 Review.
A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib.
de La Motte Rouge T, Galluzzi L, Olaussen KA, Zermati Y, Tasdemir E, Robert T, Ripoche H, Lazar V, Dessen P, Harper F, Pierron G, Pinna G, Araujo N, Harel-Belan A, Armand JP, Wong TW, Soria JC, Kroemer G. de La Motte Rouge T, et al. Cancer Res. 2007 Jul 1;67(13):6253-62. doi: 10.1158/0008-5472.CAN-07-0538. Cancer Res. 2007. PMID: 17616683
Erlotinib exhibits antineoplastic off-target effects in AML and MDS: a preclinical study.
Boehrer S, Ad├Ęs L, Braun T, Galluzzi L, Grosjean J, Fabre C, Le Roux G, Gardin C, Martin A, de Botton S, Fenaux P, Kroemer G. Boehrer S, et al. Blood. 2008 Feb 15;111(4):2170-80. doi: 10.1182/blood-2007-07-100362. Epub 2007 Oct 9. Blood. 2008. PMID: 17925489
Disruption of the hexokinase-VDAC complex for tumor therapy.
Galluzzi L, Kepp O, Tajeddine N, Kroemer G. Galluzzi L, et al. Oncogene. 2008 Aug 7;27(34):4633-5. doi: 10.1038/onc.2008.114. Epub 2008 May 12. Oncogene. 2008. PMID: 18469866
Viral control of mitochondrial apoptosis.
Galluzzi L, Brenner C, Morselli E, Touat Z, Kroemer G. Galluzzi L, et al. PLoS Pathog. 2008 May 30;4(5):e1000018. doi: 10.1371/journal.ppat.1000018. PLoS Pathog. 2008. PMID: 18516228 Free PMC article. Review.
Targeting p53 to mitochondria for cancer therapy.
Galluzzi L, Morselli E, Kepp O, Tajeddine N, Kroemer G. Galluzzi L, et al. Cell Cycle. 2008 Jul 1;7(13):1949-55. doi: 10.4161/cc.7.13.6222. Cell Cycle. 2008. PMID: 18642442 Review.
Viral subversion of immunogenic cell death.
Kepp O, Senovilla L, Galluzzi L, Panaretakis T, Tesniere A, Schlemmer F, Madeo F, Zitvogel L, Kroemer G. Kepp O, et al. Cell Cycle. 2009 Mar 15;8(6):860-9. doi: 10.4161/cc.8.6.7939. Epub 2009 Mar 26. Cell Cycle. 2009. PMID: 19221507 Review.
Anti- and pro-tumor functions of autophagy.
Morselli E, Galluzzi L, Kepp O, Vicencio JM, Criollo A, Maiuri MC, Kroemer G. Morselli E, et al. Biochim Biophys Acta. 2009 Sep;1793(9):1524-32. doi: 10.1016/j.bbamcr.2009.01.006. Epub 2009 Jan 21. Biochim Biophys Acta. 2009. PMID: 19371598 Review.
Mitochondrial gateways to cancer.
Galluzzi L, Morselli E, Kepp O, Vitale I, Rigoni A, Vacchelli E, Michaud M, Zischka H, Castedo M, Kroemer G. Galluzzi L, et al. Mol Aspects Med. 2010 Feb;31(1):1-20. doi: 10.1016/j.mam.2009.08.002. Epub 2009 Aug 19. Mol Aspects Med. 2010. PMID: 19698742 Review.
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