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FAF-Drugs2: free ADME/tox filtering tool to assist drug discovery and chemical biology projects.
Lagorce D, Sperandio O, Galons H, Miteva MA, Villoutreix BO. Lagorce D, et al. Among authors: galons h. BMC Bioinformatics. 2008 Sep 24;9:396. doi: 10.1186/1471-2105-9-396. BMC Bioinformatics. 2008. PMID: 18816385 Free PMC article.
The FAF-Drugs2 server: a multistep engine to prepare electronic chemical compound collections.
Lagorce D, Maupetit J, Baell J, Sperandio O, Tufféry P, Miteva MA, Galons H, Villoutreix BO. Lagorce D, et al. Among authors: galons h. Bioinformatics. 2011 Jul 15;27(14):2018-20. doi: 10.1093/bioinformatics/btr333. Epub 2011 Jun 2. Bioinformatics. 2011. PMID: 21636592
Therapeutic approaches of diseases related to misfolded proteins.
Galons H, Lasmezas C. Galons H, et al. Eur J Med Chem. 2016 Oct 4;121:773. doi: 10.1016/j.ejmech.2016.07.036. Eur J Med Chem. 2016. PMID: 27523642 No abstract available.
Identification of intracellular targets of small molecular weight chemical compounds using affinity chromatography.
Guiffant D, Tribouillard D, Gug F, Galons H, Meijer L, Blondel M, Bach S. Guiffant D, et al. Among authors: galons h. Biotechnol J. 2007 Jan;2(1):68-75. doi: 10.1002/biot.200600223. Biotechnol J. 2007. PMID: 17225251
Editorial - Current advances in cancer research: Therapeutics, Targets, and Chemical Biology.
Galons H, Barraja P, Papot S. Galons H, et al. Eur J Med Chem. 2017 Dec 15;142:1. doi: 10.1016/j.ejmech.2017.11.020. Eur J Med Chem. 2017. PMID: 29153409 No abstract available.
Roscovitine-derived, dual-specificity inhibitors of cyclin-dependent kinases and casein kinases 1.
Oumata N, Bettayeb K, Ferandin Y, Demange L, Lopez-Giral A, Goddard ML, Myrianthopoulos V, Mikros E, Flajolet M, Greengard P, Meijer L, Galons H. Oumata N, et al. Among authors: galons h. J Med Chem. 2008 Sep 11;51(17):5229-42. doi: 10.1021/jm800109e. Epub 2008 Aug 13. J Med Chem. 2008. PMID: 18698753
Using budding yeast to screen for anti-prion drugs.
Tribouillard D, Bach S, Gug F, Desban N, Beringue V, Andrieu T, Dormont D, Galons H, Laude H, Vilette D, Blondel M. Tribouillard D, et al. Among authors: galons h. Biotechnol J. 2006 Jan;1(1):58-67. doi: 10.1002/biot.200500001. Biotechnol J. 2006. PMID: 16892225
Roscovitine targets, protein kinases and pyridoxal kinase.
Bach S, Knockaert M, Reinhardt J, Lozach O, Schmitt S, Baratte B, Koken M, Coburn SP, Tang L, Jiang T, Liang DC, Galons H, Dierick JF, Pinna LA, Meggio F, Totzke F, Schächtele C, Lerman AS, Carnero A, Wan Y, Gray N, Meijer L. Bach S, et al. Among authors: galons h. J Biol Chem. 2005 Sep 2;280(35):31208-19. doi: 10.1074/jbc.M500806200. Epub 2005 Jun 23. J Biol Chem. 2005. PMID: 15975926
Isolation of drugs active against mammalian prions using a yeast-based screening assay.
Bach S, Talarek N, Andrieu T, Vierfond JM, Mettey Y, Galons H, Dormont D, Meijer L, Cullin C, Blondel M. Bach S, et al. Among authors: galons h. Nat Biotechnol. 2003 Sep;21(9):1075-81. doi: 10.1038/nbt855. Epub 2003 Aug 10. Nat Biotechnol. 2003. PMID: 12910243
From Drug Screening to Target Deconvolution: a Target-Based Drug Discovery Pipeline Using Leishmania Casein Kinase 1 Isoform 2 To Identify Compounds with Antileishmanial Activity.
Durieu E, Prina E, Leclercq O, Oumata N, Gaboriaud-Kolar N, Vougogiannopoulou K, Aulner N, Defontaine A, No JH, Ruchaud S, Skaltsounis AL, Galons H, Späth GF, Meijer L, Rachidi N. Durieu E, et al. Among authors: galons h. Antimicrob Agents Chemother. 2016 Apr 22;60(5):2822-33. doi: 10.1128/AAC.00021-16. Print 2016 May. Antimicrob Agents Chemother. 2016. PMID: 26902771 Free PMC article.
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