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Cholesterol oxidation products and disease: an emerging topic of interest in medicinal chemistry.
Sottero B, Gamba P, Gargiulo S, Leonarduzzi G, Poli G. Sottero B, et al. Among authors: gamba p. Curr Med Chem. 2009;16(6):685-705. doi: 10.2174/092986709787458353. Curr Med Chem. 2009. PMID: 19199932 Review.
Oxysterol-induced up-regulation of MCP-1 expression and synthesis in macrophage cells.
Leonarduzzi G, Gamba P, Sottero B, Kadl A, Robbesyn F, Calogero RA, Biasi F, Chiarpotto E, Leitinger N, Sevanian A, Poli G. Leonarduzzi G, et al. Among authors: gamba p. Free Radic Biol Med. 2005 Nov 1;39(9):1152-61. doi: 10.1016/j.freeradbiomed.2005.06.024. Epub 2005 Aug 11. Free Radic Biol Med. 2005. PMID: 16214031
Expression and synthesis of TGFbeta1 is induced in macrophages by 9-oxononanoyl cholesterol, a major cholesteryl ester oxidation product.
Sottero B, Gamba P, Longhi M, Robbesyn F, Abuja PM, Schaur RJ, Poli G, Leonarduzzi G. Sottero B, et al. Among authors: gamba p. Biofactors. 2005;24(1-4):209-16. doi: 10.1002/biof.5520240125. Biofactors. 2005. PMID: 16403982
Early involvement of ROS overproduction in apoptosis induced by 7-ketocholesterol.
Leonarduzzi G, Vizio B, Sottero B, Verde V, Gamba P, Mascia C, Chiarpotto E, Poli G, Biasi F. Leonarduzzi G, et al. Among authors: gamba p. Antioxid Redox Signal. 2006 Mar-Apr;8(3-4):375-80. doi: 10.1089/ars.2006.8.375. Antioxid Redox Signal. 2006. PMID: 16677084
Lipid peroxidation and inflammatory molecules as markers of coronary artery disease.
Sottero B, Pozzi R, Leonarduzzi G, Aroasio E, Gamba P, Gargiulo S, Rabajoli F, Ferrari F, Greco Lucchina P, Poli G. Sottero B, et al. Among authors: gamba p. Redox Rep. 2007;12(1):81-5. doi: 10.1179/135100007X162275. Redox Rep. 2007. PMID: 17263916
Oxidation as a crucial reaction for cholesterol to induce tissue degeneration: CD36 overexpression in human promonocytic cells treated with a biologically relevant oxysterol mixture.
Leonarduzzi G, Gamba P, Gargiulo S, Sottero B, Kadl A, Biasi F, Chiarpotto E, Leitinger N, Vendemiale G, Serviddio G, Poli G. Leonarduzzi G, et al. Among authors: gamba p. Aging Cell. 2008 Jun;7(3):375-82. doi: 10.1111/j.1474-9726.2008.00386.x. Epub 2008 Mar 10. Aging Cell. 2008. PMID: 18331615
The core-aldehyde 9-oxononanoyl cholesterol increases the level of transforming growth factor beta1-specific receptors on promonocytic U937 cell membranes.
Gargiulo S, Gamba P, Sottero B, Biasi F, Chiarpotto E, Serviddio G, Vendemiale G, Poli G, Leonarduzzi G. Gargiulo S, et al. Among authors: gamba p. Aging Cell. 2009 Apr;8(2):77-87. doi: 10.1111/j.1474-9726.2009.00454.x. Aging Cell. 2009. PMID: 19302374
Molecular signaling operated by a diet-compatible mixture of oxysterols in up-regulating CD36 receptor in CD68 positive cells.
Leonarduzzi G, Gargiulo S, Gamba P, Perrelli MG, Castellano I, Sapino A, Sottero B, Poli G. Leonarduzzi G, et al. Among authors: gamba p. Mol Nutr Food Res. 2010 May;54 Suppl 1:S31-41. doi: 10.1002/mnfr.200900493. Mol Nutr Food Res. 2010. PMID: 20333725
Interaction between 24-hydroxycholesterol, oxidative stress, and amyloid-β in amplifying neuronal damage in Alzheimer's disease: three partners in crime.
Gamba P, Leonarduzzi G, Tamagno E, Guglielmotto M, Testa G, Sottero B, Gargiulo S, Biasi F, Mauro A, Viña J, Poli G. Gamba P, et al. Aging Cell. 2011 Jun;10(3):403-17. doi: 10.1111/j.1474-9726.2011.00681.x. Epub 2011 Apr 5. Aging Cell. 2011. PMID: 21272192
Plaque oxysterols induce unbalanced up-regulation of matrix metalloproteinase-9 in macrophagic cells through redox-sensitive signaling pathways: Implications regarding the vulnerability of atherosclerotic lesions.
Gargiulo S, Sottero B, Gamba P, Chiarpotto E, Poli G, Leonarduzzi G. Gargiulo S, et al. Among authors: gamba p. Free Radic Biol Med. 2011 Aug 15;51(4):844-55. doi: 10.1016/j.freeradbiomed.2011.05.030. Epub 2011 May 30. Free Radic Biol Med. 2011. PMID: 21664966
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