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Regulation of fatty acid oxidation in the mammalian heart in health and disease.
Lopaschuk GD, Belke DD, Gamble J, Itoi T, Schönekess BO. Lopaschuk GD, et al. Among authors: gamble j. Biochim Biophys Acta. 1994 Aug 4;1213(3):263-76. doi: 10.1016/0005-2760(94)00082-4. Biochim Biophys Acta. 1994. PMID: 8049240 Review. No abstract available.
Insulin inhibition of 5' adenosine monophosphate-activated protein kinase in the heart results in activation of acetyl coenzyme A carboxylase and inhibition of fatty acid oxidation.
Gamble J, Lopaschuk GD. Gamble J, et al. Metabolism. 1997 Nov;46(11):1270-4. doi: 10.1016/s0026-0495(97)90229-8. Metabolism. 1997. PMID: 9361684
Upregulation of 5'-AMP-activated protein kinase is responsible for the increase in myocardial fatty acid oxidation rates following birth in the newborn rabbit.
Makinde AO, Gamble J, Lopaschuk GD. Makinde AO, et al. Among authors: gamble j. Circ Res. 1997 Apr;80(4):482-9. doi: 10.1161/01.res.80.4.482. Circ Res. 1997. PMID: 9118478
Glycolysis and glucose oxidation during reperfusion of ischemic hearts from diabetic rats.
Gamble J, Lopaschuk GD. Gamble J, et al. Biochim Biophys Acta. 1994 Jan 11;1225(2):191-9. doi: 10.1016/0925-4439(94)90078-7. Biochim Biophys Acta. 1994. PMID: 8280788
Acetyl-CoA carboxylase regulation of fatty acid oxidation in the heart.
Saddik M, Gamble J, Witters LA, Lopaschuk GD. Saddik M, et al. Among authors: gamble j. J Biol Chem. 1993 Dec 5;268(34):25836-45. J Biol Chem. 1993. PMID: 7902355
Patterns of care and outcomes differ for urban versus rural patients with newly diagnosed heart failure, even in a universal healthcare system.
Gamble JM, Eurich DT, Ezekowitz JA, Kaul P, Quan H, McAlister FA. Gamble JM, et al. Circ Heart Fail. 2011 May;4(3):317-23. doi: 10.1161/CIRCHEARTFAILURE.110.959262. Epub 2011 Mar 23. Circ Heart Fail. 2011. PMID: 21430285
L-carnitine improvement of cardiac function is associated with a stimulation in glucose but not fatty acid metabolism in carnitine-deficient hearts.
Broderick TL, Panagakis G, DiDomenico D, Gamble J, Lopaschuk GD, Shug AL, Paulson DJ. Broderick TL, et al. Among authors: gamble j. Cardiovasc Res. 1995 Nov;30(5):815-20. Cardiovasc Res. 1995. PMID: 8595631
The risk of fragility fractures in new users of dipeptidyl peptidase-4 inhibitors compared to sulfonylureas and other anti-diabetic drugs: A cohort study.
Gamble JM, Donnan JR, Chibrikov E, Twells LK, Midodzi WK, Majumdar SR. Gamble JM, et al. Diabetes Res Clin Pract. 2018 Feb;136:159-167. doi: 10.1016/j.diabres.2017.12.008. Epub 2017 Dec 16. Diabetes Res Clin Pract. 2018. PMID: 29258886
Risk of acute coronary events associated with glyburide compared with gliclazide use in patients with type 2 diabetes: a nested case-control study.
Abdelmoneim AS, Eurich DT, Gamble JM, Johnson JA, Seubert JM, Qiu W, Simpson SH. Abdelmoneim AS, et al. Among authors: gamble jm. Diabetes Obes Metab. 2014 Jan;16(1):22-9. doi: 10.1111/dom.12173. Epub 2013 Jul 19. Diabetes Obes Metab. 2014. PMID: 23802997
The darkening cloud of diabetes: do trends in cardiovascular risk management provide a silver lining?
Eurich DT, Gamble JM, Simpson SH, Johnson JA. Eurich DT, et al. Diabetes Care. 2008 Nov;31(11):2136-42. doi: 10.2337/dc08-1248. Epub 2008 Oct 7. Diabetes Care. 2008. PMID: 18840767 Free PMC article.
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