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90 results
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Structure and mechanism of DNA topoisomerase II.
Berger JM, Gamblin SJ, Harrison SC, Wang JC. Berger JM, et al. Among authors: gamblin sj. Nature. 1996 Jan 18;379(6562):225-32. doi: 10.1038/379225a0. Nature. 1996. PMID: 8538787
Structural basis of AMPK regulation by small molecule activators.
Xiao B, Sanders MJ, Carmena D, Bright NJ, Haire LF, Underwood E, Patel BR, Heath RB, Walker PA, Hallen S, Giordanetto F, Martin SR, Carling D, Gamblin SJ. Xiao B, et al. Among authors: gamblin sj. Nat Commun. 2013;4:3017. doi: 10.1038/ncomms4017. Nat Commun. 2013. PMID: 24352254 Free PMC article.
Structure of mammalian AMPK and its regulation by ADP.
Xiao B, Sanders MJ, Underwood E, Heath R, Mayer FV, Carmena D, Jing C, Walker PA, Eccleston JF, Haire LF, Saiu P, Howell SA, Aasland R, Martin SR, Carling D, Gamblin SJ. Xiao B, et al. Among authors: gamblin sj. Nature. 2011 Apr 14;472(7342):230-3. doi: 10.1038/nature09932. Epub 2011 Mar 13. Nature. 2011. PMID: 21399626 Free PMC article.
Regulation of p53 activity through lysine methylation.
Chuikov S, Kurash JK, Wilson JR, Xiao B, Justin N, Ivanov GS, McKinney K, Tempst P, Prives C, Gamblin SJ, Barlev NA, Reinberg D. Chuikov S, et al. Among authors: gamblin sj. Nature. 2004 Nov 18;432(7015):353-60. doi: 10.1038/nature03117. Epub 2004 Nov 3. Nature. 2004. PMID: 15525938
Structural basis for AMP binding to mammalian AMP-activated protein kinase.
Xiao B, Heath R, Saiu P, Leiper FC, Leone P, Jing C, Walker PA, Haire L, Eccleston JF, Davis CT, Martin SR, Carling D, Gamblin SJ. Xiao B, et al. Among authors: gamblin sj. Nature. 2007 Sep 27;449(7161):496-500. doi: 10.1038/nature06161. Epub 2007 Sep 12. Nature. 2007. PMID: 17851531
Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2.
Justin N, Zhang Y, Tarricone C, Martin SR, Chen S, Underwood E, De Marco V, Haire LF, Walker PA, Reinberg D, Wilson JR, Gamblin SJ. Justin N, et al. Among authors: gamblin sj. Nat Commun. 2016 Apr 28;7:11316. doi: 10.1038/ncomms11316. Nat Commun. 2016. PMID: 27121947 Free PMC article.
Receptor binding by H10 influenza viruses.
Vachieri SG, Xiong X, Collins PJ, Walker PA, Martin SR, Haire LF, Zhang Y, McCauley JW, Gamblin SJ, Skehel JJ. Vachieri SG, et al. Among authors: gamblin sj. Nature. 2014 Jul 24;511(7510):475-7. doi: 10.1038/nature13443. Nature. 2014. PMID: 24870229
Receptor binding by an H7N9 influenza virus from humans.
Xiong X, Martin SR, Haire LF, Wharton SA, Daniels RS, Bennett MS, McCauley JW, Collins PJ, Walker PA, Skehel JJ, Gamblin SJ. Xiong X, et al. Among authors: gamblin sj. Nature. 2013 Jul 25;499(7459):496-9. doi: 10.1038/nature12372. Nature. 2013. PMID: 23787694
Crystal structures of oseltamivir-resistant influenza virus neuraminidase mutants.
Collins PJ, Haire LF, Lin YP, Liu J, Russell RJ, Walker PA, Skehel JJ, Martin SR, Hay AJ, Gamblin SJ. Collins PJ, et al. Among authors: gamblin sj. Nature. 2008 Jun 26;453(7199):1258-61. doi: 10.1038/nature06956. Epub 2008 May 14. Nature. 2008. PMID: 18480754
The structure of H5N1 avian influenza neuraminidase suggests new opportunities for drug design.
Russell RJ, Haire LF, Stevens DJ, Collins PJ, Lin YP, Blackburn GM, Hay AJ, Gamblin SJ, Skehel JJ. Russell RJ, et al. Among authors: gamblin sj. Nature. 2006 Sep 7;443(7107):45-9. doi: 10.1038/nature05114. Epub 2006 Aug 16. Nature. 2006. PMID: 16915235
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