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A placebo-controlled double-blind randomized trial of the use of combined l-carnitine and l-acetyl-carnitine treatment in men with asthenozoospermia.
Lenzi A, et al. Fertil Steril 2004 - Clinical Trial. Among authors: Gandini L. PMID 15193480
OBJECTIVE: To determine the efficacy of combined l-carnitine and l-acetyl-carnitine therapy in infertile males with oligo-astheno-teratozoospermia. ...CONCLUSION(S): Combined treatment with l-carnitine and l-acetyl-carnitine in a controlled study of efficacy was effective in increasing sperm motility, especially in groups with lower baseline levels....
OBJECTIVE: To determine the efficacy of combined l-carnitine and l-acetyl-carnitine therapy in infertile males with oligo-asth …
Treatment with human, recombinant FSH improves sperm DNA fragmentation in idiopathic infertile men depending on the FSH receptor polymorphism p.N680S: a pharmacogenetic study
Simoni M, et al. Hum Reprod 2016 - Clinical Trial. Among authors: Gandini L. PMID 27329968
PARTICIPANTS/MATERIALS, SETTING, METHODS: Eighty-nine men with idiopathic infertility carrier of the FSHR p.N680S homozygous N or S genotype, FSH ≤ 8 IU/l and DFI >15%, were enrolled. ...
PARTICIPANTS/MATERIALS, SETTING, METHODS: Eighty-nine men with idiopathic infertility carrier of the FSHR p.N680S homozygous N or S genotype …
Altered ultrastructure of mitochondrial membranes is strongly associated with unexplained asthenozoospermia
Pelliccione F, et al. Fertil Steril 2011. Among authors: Gandini L. PMID 20840880
SETTING: Andrology Clinic, University of L'Aquila. PATIENT(S): Fifteen ejaculates with forward motility (FM) ≥ 50%, and 57 asthenozoospermic ejaculates (FM <50%, sperm vitality >50%), including 14 ejaculates with systematic genetic defects of tail principal piece, and 43 ejaculates with unexplained asthenozoospermia. ...
SETTING: Andrology Clinic, University of L'Aquila. PATIENT(S): Fifteen ejaculates with forward motility (FM) ≥ 50%, and 57 asthenozoo …
Antioxidant treatment associated with sildenafil reduces monocyte activation and markers of endothelial damage in patients with diabetic erectile dysfunction: a double-blind, placebo-controlled study
Morano S, et al. Eur Urol 2007 - Clinical Trial. Among authors: Gandini L. PMID 17478034
OBJECTIVE: To investigate the synergic effect of propionyl L-carnitine (PLC) plus sildenafil in reducing monocyte oxidative activity and endothelial dysfunction markers in diabetic patients with erectile dysfunction (ED). ...
OBJECTIVE: To investigate the synergic effect of propionyl L-carnitine (PLC) plus sildenafil in reducing monocyte oxidative activity …
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