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Ganoderma lucidum reduces obesity in mice by modulating the composition of the gut microbiota.
Chang CJ, Lin CS, Lu CC, Martel J, Ko YF, Ojcius DM, Tseng SF, Wu TR, Chen YY, Young JD, Lai HC. Chang CJ, et al. Nat Commun. 2015 Jun 23;6:7489. doi: 10.1038/ncomms8489. Nat Commun. 2015. PMID: 26102296 Free PMC article.
Obesity is associated with low-grade chronic inflammation and intestinal dysbiosis. ...We further show that high molecular weight polysaccharides (>300 kDa) isolated from the WEGL extract produce similar anti-obesity and microbiota-modulating effects. Our results
Obesity is associated with low-grade chronic inflammation and intestinal dysbiosis. ...We further show that high molecular weight pol
Ganoderma Lucidum Polysaccharide Peptide Alleviates Hepatoteatosis via Modulating Bile Acid Metabolism Dependent on FXR-SHP/FGF.
Zhong D, Xie Z, Huang B, Zhu S, Wang G, Zhou H, Lin S, Lin Z, Yang B. Zhong D, et al. Cell Physiol Biochem. 2018;49(3):1163-1179. doi: 10.1159/000493297. Epub 2018 Sep 7. Cell Physiol Biochem. 2018. PMID: 30196282 Free article.
BACKGROUND/AIMS: Non-alcoholic fatty liver disease (NAFLD) encompasses a series of pathologic changes ranging from steatosis to steatohepatitis, which may progress to cirrhosis and hepatocellular carcinoma. The purpose of this study was to determine whether ganoderma lucid …
BACKGROUND/AIMS: Non-alcoholic fatty liver disease (NAFLD) encompasses a series of pathologic changes ranging from steatosis to steatohepati …
Dietary Factors and Supplements Influencing Prostate Specific-Antigen (PSA) Concentrations in Men with Prostate Cancer and Increased Cancer Risk: An Evidence Analysis Review Based on Randomized Controlled Trials.
Grammatikopoulou MG, Gkiouras K, Papageorgiou SΤ, Myrogiannis I, Mykoniatis I, Papamitsou T, Bogdanos DP, Goulis DG. Grammatikopoulou MG, et al. Nutrients. 2020 Sep 29;12(10):2985. doi: 10.3390/nu12102985. Nutrients. 2020. PMID: 33003518 Free PMC article. Review.
Several antioxidants, including lycopene, selenium, curcumin, coenzyme Q10, phytoestrogens (including isoflavones and flavonoids), green tea catechins, cernitin, vitamins (C, E, D) and multivitamins, medicinal mushrooms (Ganoderma lucidum), fruit extracts (saw palmetto, cr …
Several antioxidants, including lycopene, selenium, curcumin, coenzyme Q10, phytoestrogens (including isoflavones and flavonoids), green tea …
Identification of novel phytocannabinoids from Ganoderma by label-free dynamic mass redistribution assay.
Zhou H, Peng X, Hou T, Zhao N, Qiu M, Zhang X, Liang X. Zhou H, et al. J Ethnopharmacol. 2020 Jan 10;246:112218. doi: 10.1016/j.jep.2019.112218. Epub 2019 Sep 5. J Ethnopharmacol. 2020. PMID: 31494202
Zhang; Ganoderma capense (Lloyd) Teng, Zhong Guo De Zhen Jun; Ganoderma cochlear (Blume & T. Nees) Bres., Hedwigia; Ganoderma resinaceum Boud.; Ganoderma applanatum (Pers.) Pat.; Carthamus tinctorius L. ...
Zhang; Ganoderma capense (Lloyd) Teng, Zhong Guo De Zhen Jun; Ganoderma cochlear (Blume & T. Nees) Bres., Hedwigia; Gan
Ganoderma Lucidum Polysaccharides Ameliorates Hepatic Steatosis and Oxidative Stress in db/db Mice via Targeting Nuclear Factor E2 (Erythroid-Derived 2)-Related Factor-2/Heme Oxygenase-1 (HO-1) Pathway.
Li HN, Zhao LL, Zhou DY, Chen DQ. Li HN, et al. Med Sci Monit. 2020 Apr 4;26:e921905. doi: 10.12659/MSM.921905. Med Sci Monit. 2020. PMID: 32245940 Free PMC article.
BACKGROUND Type 2 diabetes mellitus (T2DM) and its comorbidities, including obesity, hypertension, and hyperlipidemia, are commonly associated with non-alcoholic fatty liver disease (NAFLD). Ganoderma lucidum polysaccharide (GDLP) is one of the central bioactive com …
BACKGROUND Type 2 diabetes mellitus (T2DM) and its comorbidities, including obesity, hypertension, and hyperlipidemia, are commonly a …
Ganoderma lucidum Extract Reduces Insulin Resistance by Enhancing AMPK Activation in High-Fat Diet-Induced Obese Mice.
Lee HA, Cho JH, Afinanisa Q, An GH, Han JG, Kang HJ, Choi SH, Seong HA. Lee HA, et al. Nutrients. 2020 Oct 30;12(11):3338. doi: 10.3390/nu12113338. Nutrients. 2020. PMID: 33142995 Free PMC article.
Ganoderma lucidum is used widely in oriental medicine to treat obesity and metabolic diseases. ...Together, these findings demonstrate that G. lucidum may effectively prevent obesity and suppress obesity-induced insulin resistance via AMPK activation..
Ganoderma lucidum is used widely in oriental medicine to treat obesity and metabolic diseases. ...Together, these findings dem
Triterpenoids from functional mushroom Ganoderma resinaceum and the novel role of Resinacein S in enhancing the activity of brown/beige adipocytes.
Huang Y, Wei G, Peng X, Hu G, Su H, Liu J, Chen X, Qiu M. Huang Y, et al. Food Res Int. 2020 Oct;136:109303. doi: 10.1016/j.foodres.2020.109303. Epub 2020 May 11. Food Res Int. 2020. PMID: 32846515
As the major biologically active constituents in Ganoderma species, Ganoderma triterpenoids (GTs) also showed potential anti-obesity effect in recent reports. ...In conclusion, Res S is potential for activating the function of brown and beige adipocyte …
As the major biologically active constituents in Ganoderma species, Ganoderma triterpenoids (GTs) also showed potential anti- …
Gut microbiota: Ganoderma lucidum, a new prebiotic agent to treat obesity?
Delzenne NM, Bindels LB. Delzenne NM, et al. Nat Rev Gastroenterol Hepatol. 2015 Oct;12(10):553-4. doi: 10.1038/nrgastro.2015.137. Epub 2015 Aug 18. Nat Rev Gastroenterol Hepatol. 2015. PMID: 26284561
Modulation of the gut microbiota is one of the promising tools to tackle obesity. Chang and colleagues have recently shown that an extract of the mushroom Ganoderma lucidum, a traditional remedy in Asia, can reduce obesity in mice by modulating the gut microb …
Modulation of the gut microbiota is one of the promising tools to tackle obesity. Chang and colleagues have recently shown that an ex …
Suppression of obesity and inflammation by polysaccharide from sporoderm-broken spore of Ganoderma lucidum via gut microbiota regulation.
Sang T, Guo C, Guo D, Wu J, Wang Y, Wang Y, Chen J, Chen C, Wu K, Na K, Li K, Fang L, Guo C, Wang X. Sang T, et al. Carbohydr Polym. 2021 Mar 15;256:117594. doi: 10.1016/j.carbpol.2020.117594. Epub 2021 Jan 4. Carbohydr Polym. 2021. PMID: 33483079
Ganoderma lucidum has been shown to have anti-obesity effects. However, polysaccharide extracted from the sporoderm-broken spores of Ganoderma lucidum (BSGLP) against obesity and its underlying mechanisms have never been reported. In the current study,
Ganoderma lucidum has been shown to have anti-obesity effects. However, polysaccharide extracted from the sporoderm-broken spo
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