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TDP-43 represses cryptic exon inclusion in the FTD-ALS gene UNC13A.
Ma XR, Prudencio M, Koike Y, Vatsavayai SC, Kim G, Harbinski F, Briner A, Rodriguez CM, Guo C, Akiyama T, Schmidt HB, Cummings BB, Wyatt DW, Kurylo K, Miller G, Mekhoubad S, Sallee N, Mekonnen G, Ganser L, Rubien JD, Jansen-West K, Cook CN, Pickles S, Oskarsson B, Graff-Radford NR, Boeve BF, Knopman DS, Petersen RC, Dickson DW, Shorter J, Myong S, Green EM, Seeley WW, Petrucelli L, Gitler AD. Ma XR, et al. Among authors: ganser l. Nature. 2022 Mar;603(7899):124-130. doi: 10.1038/s41586-022-04424-7. Epub 2022 Feb 23. Nature. 2022. PMID: 35197626 Free PMC article.
Poly(ADP-ribose) drives condensation of FUS via a transient interaction.
Rhine K, Dasovich M, Yoniles J, Badiee M, Skanchy S, Ganser LR, Ge Y, Fare CM, Shorter J, Leung AKL, Myong S. Rhine K, et al. Among authors: ganser lr. Mol Cell. 2022 Mar 3;82(5):969-985.e11. doi: 10.1016/j.molcel.2022.01.018. Epub 2022 Feb 18. Mol Cell. 2022. PMID: 35182479 Free PMC article.
RNA conformational propensities determine cellular activity.
Ken ML, Roy R, Geng A, Ganser LR, Manghrani A, Cullen BR, Schulze-Gahmen U, Herschlag D, Al-Hashimi HM. Ken ML, et al. Among authors: ganser lr. Nature. 2023 May;617(7962):835-841. doi: 10.1038/s41586-023-06080-x. Epub 2023 May 17. Nature. 2023. PMID: 37198487 Free PMC article.
31 results