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A transchromosomic rat model with human chromosome 21 shows robust Down syndrome features.
Kazuki Y, Gao FJ, Yamakawa M, Hirabayashi M, Kazuki K, Kajitani N, Miyagawa-Tomita S, Abe S, Sanbo M, Hara H, Kuniishi H, Ichisaka S, Hata Y, Koshima M, Takayama H, Takehara S, Nakayama Y, Hiratsuka M, Iida Y, Matsukura S, Noda N, Li Y, Moyer AJ, Cheng B, Singh N, Richtsmeier JT, Oshimura M, Reeves RH. Kazuki Y, et al. Among authors: gao fj. Am J Hum Genet. 2022 Feb 3;109(2):328-344. doi: 10.1016/j.ajhg.2021.12.015. Epub 2022 Jan 24. Am J Hum Genet. 2022. PMID: 35077668 Free PMC article.
A non-mosaic transchromosomic mouse model of down syndrome carrying the long arm of human chromosome 21.
Kazuki Y, Gao FJ, Li Y, Moyer AJ, Devenney B, Hiramatsu K, Miyagawa-Tomita S, Abe S, Kazuki K, Kajitani N, Uno N, Takehara S, Takiguchi M, Yamakawa M, Hasegawa A, Shimizu R, Matsukura S, Noda N, Ogonuki N, Inoue K, Matoba S, Ogura A, Florea LD, Savonenko A, Xiao M, Wu D, Batista DA, Yang J, Qiu Z, Singh N, Richtsmeier JT, Takeuchi T, Oshimura M, Reeves RH. Kazuki Y, et al. Among authors: gao fj. Elife. 2020 Jun 29;9:e56223. doi: 10.7554/eLife.56223. Elife. 2020. PMID: 32597754 Free PMC article.
Hypermetabolism in mice carrying a near complete human chromosome 21.
Sarver DC, Xu C, Rodriguez S, Aja S, Jaffe AE, Gao FJ, Delannoy M, Periasamy M, Kazuki Y, Oshimura M, Reeves RH, Wong GW. Sarver DC, et al. Among authors: gao fj. bioRxiv [Preprint]. 2023 Jan 31:2023.01.30.526183. doi: 10.1101/2023.01.30.526183. bioRxiv. 2023. PMID: 36778465 Free PMC article. Updated. Preprint.
Hypermetabolism in mice carrying a near-complete human chromosome 21.
Sarver DC, Xu C, Rodriguez S, Aja S, Jaffe AE, Gao FJ, Delannoy M, Periasamy M, Kazuki Y, Oshimura M, Reeves RH, Wong GW. Sarver DC, et al. Among authors: gao fj. Elife. 2023 May 30;12:e86023. doi: 10.7554/eLife.86023. Elife. 2023. PMID: 37249575 Free PMC article.
51 results