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Year Number of Results
2011 1
2012 1
2013 3
2014 4
2015 2
2018 1
2020 1
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11 results
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Alcohol and endogenous aldehydes damage chromosomes and mutate stem cells.
Garaycoechea JI, Crossan GP, Langevin F, Mulderrig L, Louzada S, Yang F, Guilbaud G, Park N, Roerink S, Nik-Zainal S, Stratton MR, Patel KJ. Garaycoechea JI, et al. Nature. 2018 Jan 11;553(7687):171-177. doi: 10.1038/nature25154. Epub 2018 Jan 3. Nature. 2018. PMID: 29323295 Free PMC article.
Endogenous Formaldehyde Is a Hematopoietic Stem Cell Genotoxin and Metabolic Carcinogen.
Pontel LB, Rosado IV, Burgos-Barragan G, Garaycoechea JI, Yu R, Arends MJ, Chandrasekaran G, Broecker V, Wei W, Liu L, Swenberg JA, Crossan GP, Patel KJ. Pontel LB, et al. Among authors: garaycoechea ji. Mol Cell. 2015 Oct 1;60(1):177-88. doi: 10.1016/j.molcel.2015.08.020. Epub 2015 Sep 24. Mol Cell. 2015. PMID: 26412304 Free PMC article.
Do mutational dynamics in stem cells explain the origin of common cancers?
Crossan GP, Garaycoechea JI, Patel KJ. Crossan GP, et al. Among authors: garaycoechea ji. Cell Stem Cell. 2015 Feb 5;16(2):111-2. doi: 10.1016/j.stem.2015.01.009. Cell Stem Cell. 2015. PMID: 25658366 Free article.
Why does the bone marrow fail in Fanconi anemia?
Garaycoechea JI, Patel KJ. Garaycoechea JI, et al. Blood. 2014 Jan 2;123(1):26-34. doi: 10.1182/blood-2013-09-427740. Epub 2013 Nov 7. Blood. 2014. PMID: 24200684 Review.
Abundance of the Fanconi anaemia core complex is regulated by the RuvBL1 and RuvBL2 AAA+ ATPases.
Rajendra E, Garaycoechea JI, Patel KJ, Passmore LA. Rajendra E, et al. Among authors: garaycoechea ji. Nucleic Acids Res. 2014 Dec 16;42(22):13736-48. doi: 10.1093/nar/gku1230. Epub 2014 Nov 26. Nucleic Acids Res. 2014. PMID: 25428364 Free PMC article.
XPF-ERCC1 protects liver, kidney and blood homeostasis outside the canonical excision repair pathways.
Mulderrig L, Garaycoechea JI. Mulderrig L, et al. Among authors: garaycoechea ji. PLoS Genet. 2020 Apr 9;16(4):e1008555. doi: 10.1371/journal.pgen.1008555. eCollection 2020 Apr. PLoS Genet. 2020. PMID: 32271760 Free PMC article.
Biocatalysed halogenation of nucleobase analogues.
Médici R, Garaycoechea JI, Dettorre LA, Iribarren AM, Lewkowicz ES. Médici R, et al. Among authors: garaycoechea ji. Biotechnol Lett. 2011 Oct;33(10):1999-2003. doi: 10.1007/s10529-011-0655-z. Epub 2011 Jun 10. Biotechnol Lett. 2011. PMID: 21660577
[Aldehydes and Fanconi anaemia: the enemy within].
Langevin FP, Garaycoechea JI, Crossan GP, Patel KJ. Langevin FP, et al. Among authors: garaycoechea ji. Med Sci (Paris). 2013 Apr;29(4):361-4. doi: 10.1051/medsci/2013294009. Epub 2013 Apr 26. Med Sci (Paris). 2013. PMID: 23621931 Free article. French. No abstract available.
Mouse SLX4 is a tumor suppressor that stimulates the activity of the nuclease XPF-ERCC1 in DNA crosslink repair.
Hodskinson MR, Silhan J, Crossan GP, Garaycoechea JI, Mukherjee S, Johnson CM, Schärer OD, Patel KJ. Hodskinson MR, et al. Among authors: garaycoechea ji. Mol Cell. 2014 May 8;54(3):472-84. doi: 10.1016/j.molcel.2014.03.014. Epub 2014 Apr 10. Mol Cell. 2014. PMID: 24726326 Free PMC article.
Genotoxic consequences of endogenous aldehydes on mouse haematopoietic stem cell function.
Garaycoechea JI, Crossan GP, Langevin F, Daly M, Arends MJ, Patel KJ. Garaycoechea JI, et al. Nature. 2012 Sep 27;489(7417):571-5. doi: 10.1038/nature11368. Epub 2012 Aug 26. Nature. 2012. PMID: 22922648
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