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Molecular mechanisms of thrombin-induced endothelial cell permeability.
Bogatcheva NV, Garcia JG, Verin AD. Bogatcheva NV, et al. Biochemistry (Mosc). 2002 Jan;67(1):75-84. doi: 10.1023/a:1013904231324. Biochemistry (Mosc). 2002. PMID: 11841342 Review.
Polymorphisms in the myosin light chain kinase gene that confer risk of severe sepsis are associated with a lower risk of asthma.
Gao L, Grant AV, Rafaels N, Stockton-Porter M, Watkins T, Gao P, Chi P, Muñoz M, Watson H, Dunston G, Togias A, Hansel N, Sevransky J, Maloney JP, Moss M, Shanholtz C, Brower R, Garcia JG, Grigoryev DN, Cheadle C, Beaty TH, Mathias RA, Barnes KC. Gao L, et al. J Allergy Clin Immunol. 2007 May;119(5):1111-8. doi: 10.1016/j.jaci.2007.03.019. J Allergy Clin Immunol. 2007. PMID: 17472811
Activated protein C protects against ventilator-induced pulmonary capillary leak.
Finigan JH, Boueiz A, Wilkinson E, Damico R, Skirball J, Pae HH, Damarla M, Hasan E, Pearse DB, Reddy SP, Grigoryev DN, Cheadle C, Esmon CT, Garcia JG, Hassoun PM. Finigan JH, et al. Am J Physiol Lung Cell Mol Physiol. 2009 Jun;296(6):L1002-11. doi: 10.1152/ajplung.90555.2008. Epub 2009 Apr 10. Am J Physiol Lung Cell Mol Physiol. 2009. PMID: 19363121 Free PMC article.
Caldesmon is a cytoskeletal target for PKC in endothelium.
Bogatcheva NV, Birukova A, Borbiev T, Kolosova I, Liu F, Garcia JG, Verin AD. Bogatcheva NV, et al. J Cell Biochem. 2006 Dec 15;99(6):1593-605. doi: 10.1002/jcb.20823. J Cell Biochem. 2006. PMID: 16823797
Mechanical stress activates xanthine oxidoreductase through MAP kinase-dependent pathways.
Abdulnour RE, Peng X, Finigan JH, Han EJ, Hasan EJ, Birukov KG, Reddy SP, Watkins JE 3rd, Kayyali US, Garcia JG, Tuder RM, Hassoun PM. Abdulnour RE, et al. Am J Physiol Lung Cell Mol Physiol. 2006 Sep;291(3):L345-53. doi: 10.1152/ajplung.00453.2005. Epub 2006 Apr 21. Am J Physiol Lung Cell Mol Physiol. 2006. PMID: 16632522
Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation.
Finigan JH, Dudek SM, Singleton PA, Chiang ET, Jacobson JR, Camp SM, Ye SQ, Garcia JG. Finigan JH, et al. J Biol Chem. 2005 Apr 29;280(17):17286-93. doi: 10.1074/jbc.M412427200. Epub 2005 Feb 14. J Biol Chem. 2005. PMID: 15710622
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