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Structural analysis of strand misalignment during DNA synthesis by a human DNA polymerase.
Garcia-Diaz M, Bebenek K, Krahn JM, Pedersen LC, Kunkel TA. Garcia-Diaz M, et al. Cell. 2006 Jan 27;124(2):331-42. doi: 10.1016/j.cell.2005.10.039. Cell. 2006. PMID: 16439207
Helix unwinding and base flipping enable human MTERF1 to terminate mitochondrial transcription.
Yakubovskaya E, Mejia E, Byrnes J, Hambardjieva E, Garcia-Diaz M. Yakubovskaya E, et al. Cell. 2010 Jun 11;141(6):982-93. doi: 10.1016/j.cell.2010.05.018. Cell. 2010. PMID: 20550934 Free PMC article.
Structural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles.
Aleem S, Georghiou G, Kleiner RE, Guja K, Craddock BP, Lyczek A, Chan AI, Garcia-Diaz M, Miller WT, Liu DR, Seeliger MA. Aleem S, et al. Cell Chem Biol. 2016 Sep 22;23(9):1103-1112. doi: 10.1016/j.chembiol.2016.07.017. Epub 2016 Sep 1. Cell Chem Biol. 2016. PMID: 27593110 Free PMC article.
A fidelity mechanism in DNA polymerase lambda promotes error-free bypass of 8-oxo-dG.
Burak MJ, Guja KE, Hambardjieva E, Derkunt B, Garcia-Diaz M. Burak MJ, et al. EMBO J. 2016 Sep 15;35(18):2045-59. doi: 10.15252/embj.201694332. Epub 2016 Aug 1. EMBO J. 2016. PMID: 27481934 Free PMC article.
Biochemical Characterization of the Human Mitochondrial Replicative Twinkle Helicase: SUBSTRATE SPECIFICITY, DNA BRANCH MIGRATION, AND ABILITY TO OVERCOME BLOCKADES TO DNA UNWINDING.
Khan I, Crouch JD, Bharti SK, Sommers JA, Carney SM, Yakubovskaya E, Garcia-Diaz M, Trakselis MA, Brosh RM Jr. Khan I, et al. J Biol Chem. 2016 Jul 1;291(27):14324-39. doi: 10.1074/jbc.M115.712026. Epub 2016 May 11. J Biol Chem. 2016. PMID: 27226550 Free PMC article.
Organization of the human mitochondrial transcription initiation complex.
Yakubovskaya E, Guja KE, Eng ET, Choi WS, Mejia E, Beglov D, Lukin M, Kozakov D, Garcia-Diaz M. Yakubovskaya E, et al. Nucleic Acids Res. 2014 Apr;42(6):4100-12. doi: 10.1093/nar/gkt1360. Epub 2014 Jan 9. Nucleic Acids Res. 2014. PMID: 24413562 Free PMC article.
A remote palm domain residue of RB69 DNA polymerase is critical for enzyme activity and influences the conformation of the active site.
Jacewicz A, Trzemecka A, Guja KE, Plochocka D, Yakubovskaya E, Bebenek A, Garcia-Diaz M. Jacewicz A, et al. PLoS One. 2013 Oct 7;8(10):e76700. doi: 10.1371/journal.pone.0076700. eCollection 2013. PLoS One. 2013. PMID: 24116139 Free PMC article.
Structures of the Leishmania infantum polymerase beta.
Mejia E, Burak M, Alonso A, Larraga V, Kunkel TA, Bebenek K, Garcia-Diaz M. Mejia E, et al. DNA Repair (Amst). 2014 Jun;18:1-9. doi: 10.1016/j.dnarep.2014.03.001. Epub 2014 Mar 22. DNA Repair (Amst). 2014. PMID: 24666693 Free PMC article.
Multiple functions of DNA polymerases.
Garcia-Diaz M, Bebenek K. Garcia-Diaz M, et al. CRC Crit Rev Plant Sci. 2007 Mar;26(2):105-122. doi: 10.1080/07352680701252817. CRC Crit Rev Plant Sci. 2007. PMID: 18496613 Free PMC article.
The X family portrait: structural insights into biological functions of X family polymerases.
Moon AF, Garcia-Diaz M, Batra VK, Beard WA, Bebenek K, Kunkel TA, Wilson SH, Pedersen LC. Moon AF, et al. DNA Repair (Amst). 2007 Dec 1;6(12):1709-25. doi: 10.1016/j.dnarep.2007.05.009. Epub 2007 Jul 12. DNA Repair (Amst). 2007. PMID: 17631059 Free PMC article. Review.
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