Garcia-Echeverria C - Search Results

1

Identification of novel mdm2 binding peptides by phage display.

Böttger V, Böttger A, Howard SF, Picksley SM, Chène P, Garcia-Echeverria C, Hochkeppel HK, Lane DP. Böttger V, et al. Oncogene. 1996 Nov 21;13(10):2141-7. Oncogene. 1996. PMID: 8950981

2

Molecular characterization of the hdm2-p53 interaction.

Böttger A, Böttger V, Garcia-Echeverria C, Chène P, Hochkeppel HK, Sampson W, Ang K, Howard SF, Picksley SM, Lane DP. Böttger A, et al. J Mol Biol. 1997 Jun 27;269(5):744-56. doi: 10.1006/jmbi.1997.1078. J Mol Biol. 1997. PMID: 9223638

3

Comparative study of the p53-mdm2 and p53-MDMX interfaces.

Böttger V, Böttger A, Garcia-Echeverria C, Ramos YF, van der Eb AJ, Jochemsen AG, Lane DP. Böttger V, et al. Oncogene. 1999 Jan 7;18(1):189-99. doi: 10.1038/sj.onc.1202281. Oncogene. 1999. PMID: 9926934

4

Coupling of the antennapedia third helix to a potent antagonist of the p53/hdm2 protein-protein interaction.

García-Echeverría C, Furet P, Chène P. García-Echeverría C, et al. Bioorg Med Chem Lett. 2001 Aug 20;11(16):2161-4. doi: 10.1016/s0960-894x(01)00394-8. Bioorg Med Chem Lett. 2001. PMID: 11514160

5

A small synthetic peptide, which inhibits the p53-hdm2 interaction, stimulates the p53 pathway in tumour cell lines.

Chène P, Fuchs J, Bohn J, García-Echeverría C, Furet P, Fabbro D. Chène P, et al. J Mol Biol. 2000 May 26;299(1):245-53. doi: 10.1006/jmbi.2000.3738. J Mol Biol. 2000. PMID: 10860736

6

Study of the cytotoxic effect of a peptidic inhibitor of the p53-hdm2 interaction in tumor cells.

Chène P, Fuchs J, Carena I, Furet P, García-Echeverría C. Chène P, et al. FEBS Lett. 2002 Oct 9;529(2-3):293-7. doi: 10.1016/s0014-5793(02)03362-8. FEBS Lett. 2002. PMID: 12372616 Free article.

7

Discovery of potent antagonists of the interaction between human double minute 2 and tumor suppressor p53.

García-Echeverría C, Chène P, Blommers MJ, Furet P. García-Echeverría C, et al. J Med Chem. 2000 Aug 24;43(17):3205-8. doi: 10.1021/jm990966p. J Med Chem. 2000. PMID: 10966738 No abstract available.

8

Dual specificity of Src homology 2 domains for phosphotyrosine peptide ligands.

Gay B, Furet P, García-Echeverría C, Rahuel J, Chène P, Fretz H, Schoepfer J, Caravatti G. Gay B, et al. Biochemistry. 1997 May 13;36(19):5712-8. doi: 10.1021/bi962642y. Biochemistry. 1997. PMID: 9153411

9

Combining hit identification strategies: fragment-based and in silico approaches to orally active 2-aminothieno[2,3-d]pyrimidine inhibitors of the Hsp90 molecular chaperone.

Brough PA, Barril X, Borgognoni J, Chene P, Davies NG, Davis B, Drysdale MJ, Dymock B, Eccles SA, Garcia-Echeverria C, Fromont C, Hayes A, Hubbard RE, Jordan AM, Jensen MR, Massey A, Merrett A, Padfield A, Parsons R, Radimerski T, Raynaud FI, Robertson A, Roughley SD, Schoepfer J, Simmonite H, Sharp SY, Surgenor A, Valenti M, Walls S, Webb P, Wood M, Workman P, Wright L. Brough PA, et al. J Med Chem. 2009 Aug 13;52(15):4794-809. doi: 10.1021/jm900357y. J Med Chem. 2009. PMID: 19610616

10

Inhibition of Aurora A in response to DNA damage.

Krystyniak A, Garcia-Echeverria C, Prigent C, Ferrari S. Krystyniak A, et al. Oncogene. 2006 Jan 19;25(3):338-48. doi: 10.1038/sj.onc.1209056. Oncogene. 2006. PMID: 16158051

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