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Molecular Mechanisms of Class B GPCR Activation: Insights from Adrenomedullin Receptors.
Garelja ML, Au M, Brimble MA, Gingell JJ, Hendrikse ER, Lovell A, Prodan N, Sexton PM, Siow A, Walker CS, Watkins HA, Williams GM, Wootten D, Yang SH, Harris PWR, Hay DL. Garelja ML, et al. ACS Pharmacol Transl Sci. 2020 Feb 26;3(2):246-262. doi: 10.1021/acsptsci.9b00083. eCollection 2020 Apr 10. ACS Pharmacol Transl Sci. 2020. PMID: 32296766 Free PMC article.
Photoaffinity Cross-Linking and Unnatural Amino Acid Mutagenesis Reveal Insights into Calcitonin Gene-Related Peptide Binding to the Calcitonin Receptor-like Receptor/Receptor Activity-Modifying Protein 1 (CLR/RAMP1) Complex.
Simms J, Uddin R, Sakmar TP, Gingell JJ, Garelja ML, Hay DL, Brimble MA, Harris PW, Reynolds CA, Poyner DR. Simms J, et al. Among authors: garelja ml. Biochemistry. 2018 Aug 14;57(32):4915-4922. doi: 10.1021/acs.biochem.8b00502. Epub 2018 Jul 25. Biochemistry. 2018. PMID: 30004692 Free article.
Receptor activity-modifying protein dependent and independent activation mechanisms in the coupling of calcitonin gene-related peptide and adrenomedullin receptors to Gs.
Woolley MJ, Reynolds CA, Simms J, Walker CS, Mobarec JC, Garelja ML, Conner AC, Poyner DR, Hay DL. Woolley MJ, et al. Among authors: garelja ml. Biochem Pharmacol. 2017 Oct 15;142:96-110. doi: 10.1016/j.bcp.2017.07.005. Epub 2017 Jul 11. Biochem Pharmacol. 2017. PMID: 28705698 Free PMC article.