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A new progeroid syndrome reveals that genotoxic stress suppresses the somatotroph axis.
Niedernhofer LJ, Garinis GA, Raams A, Lalai AS, Robinson AR, Appeldoorn E, Odijk H, Oostendorp R, Ahmad A, van Leeuwen W, Theil AF, Vermeulen W, van der Horst GT, Meinecke P, Kleijer WJ, Vijg J, Jaspers NG, Hoeijmakers JH. Niedernhofer LJ, et al. Among authors: garinis ga. Nature. 2006 Dec 21;444(7122):1038-43. doi: 10.1038/nature05456. Nature. 2006. PMID: 17183314
Differential role of basal keratinocytes in UV-induced immunosuppression and skin cancer.
Jans J, Garinis GA, Schul W, van Oudenaren A, Moorhouse M, Smid M, Sert YG, van der Velde A, Rijksen Y, de Gruijl FR, van der Spek PJ, Yasui A, Hoeijmakers JH, Leenen PJ, van der Horst GT. Jans J, et al. Among authors: garinis ga. Mol Cell Biol. 2006 Nov;26(22):8515-26. doi: 10.1128/MCB.00807-06. Epub 2006 Sep 11. Mol Cell Biol. 2006. PMID: 16966369 Free PMC article.
Impaired genome maintenance suppresses the growth hormone--insulin-like growth factor 1 axis in mice with Cockayne syndrome.
van der Pluijm I, Garinis GA, Brandt RM, Gorgels TG, Wijnhoven SW, Diderich KE, de Wit J, Mitchell JR, van Oostrom C, Beems R, Niedernhofer LJ, Velasco S, Friedberg EC, Tanaka K, van Steeg H, Hoeijmakers JH, van der Horst GT. van der Pluijm I, et al. Among authors: garinis ga. PLoS Biol. 2007 Jan;5(1):e2. doi: 10.1371/journal.pbio.0050002. PLoS Biol. 2007. PMID: 17326724 Free PMC article.
Age to survive: DNA damage and aging.
Schumacher B, Garinis GA, Hoeijmakers JH. Schumacher B, et al. Among authors: garinis ga. Trends Genet. 2008 Feb;24(2):77-85. doi: 10.1016/j.tig.2007.11.004. Epub 2008 Jan 14. Trends Genet. 2008. PMID: 18192065 Review.
Delayed and accelerated aging share common longevity assurance mechanisms.
Schumacher B, van der Pluijm I, Moorhouse MJ, Kosteas T, Robinson AR, Suh Y, Breit TM, van Steeg H, Niedernhofer LJ, van Ijcken W, Bartke A, Spindler SR, Hoeijmakers JH, van der Horst GT, Garinis GA. Schumacher B, et al. Among authors: garinis ga. PLoS Genet. 2008 Aug 15;4(8):e1000161. doi: 10.1371/journal.pgen.1000161. PLoS Genet. 2008. PMID: 18704162 Free PMC article.
62 results