Rapid and sustained improvement in bone and cartilage turnover markers with the anti-interleukin-6 receptor inhibitor tocilizumab plus methotrexate in rheumatoid arthritis patients with an inadequate response to methotrexate: results from a substudy of the multicenter double-blind, placebo-controlled trial of tocilizumab in inadequate responders to methotrexate alone.
Arthritis Rheum. 2010 Jan;62(1):33-43. doi: 10.1002/art.25053.
Arthritis Rheum. 2010.
PMID: 20039425
Clinical Trial.