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Page 1
Locking CBL TKBD in its native conformation presents a novel therapeutic opportunity in mutant CBL-dependent leukemia.
Ahmed SF, Anand J, Zhang W, Buetow L, Rishi L, Mitchell L, Bohlen J, Lilla S, Sibbet GJ, Nixon C, Patel A, Majorek KA, Zanivan S, Bustamante JC, Sidhu SS, Blyth K, Huang DT. Ahmed SF, et al. Among authors: sibbet gj. Mol Ther. 2025 Aug 6;33(8):3624-3643. doi: 10.1016/j.ymthe.2025.04.042. Epub 2025 May 5. Mol Ther. 2025. PMID: 40329529 Free article.
Structural basis for DNA damage-induced phosphoregulation of MDM2 RING domain.
Magnussen HM, Ahmed SF, Sibbet GJ, Hristova VA, Nomura K, Hock AK, Archibald LJ, Jamieson AG, Fushman D, Vousden KH, Weissman AM, Huang DT. Magnussen HM, et al. Among authors: sibbet gj. Nat Commun. 2020 Apr 29;11(1):2094. doi: 10.1038/s41467-020-15783-y. Nat Commun. 2020. PMID: 32350255 Free PMC article.
16 results