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210 results

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Page 1
Preclinical and clinical efficacy of XPO1/CRM1 inhibition by the karyopherin inhibitor KPT-330 in Ph+ leukemias.
Walker CJ, Oaks JJ, Santhanam R, Neviani P, Harb JG, Ferenchak G, Ellis JJ, Landesman Y, Eisfeld AK, Gabrail NY, Smith CL, Caligiuri MA, Hokland P, Roy DC, Reid A, Milojkovic D, Goldman JM, Apperley J, Garzon R, Marcucci G, Shacham S, Kauffman MG, Perrotti D. Walker CJ, et al. Among authors: garzon r. Blood. 2013 Oct 24;122(17):3034-44. doi: 10.1182/blood-2013-04-495374. Epub 2013 Aug 22. Blood. 2013. PMID: 23970380 Free PMC article.
MicroRNA fingerprints during human megakaryocytopoiesis.
Garzon R, Pichiorri F, Palumbo T, Iuliano R, Cimmino A, Aqeilan R, Volinia S, Bhatt D, Alder H, Marcucci G, Calin GA, Liu CG, Bloomfield CD, Andreeff M, Croce CM. Garzon R, et al. Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5078-83. doi: 10.1073/pnas.0600587103. Epub 2006 Mar 20. Proc Natl Acad Sci U S A. 2006. PMID: 16549775 Free PMC article.
Bortezomib induces DNA hypomethylation and silenced gene transcription by interfering with Sp1/NF-kappaB-dependent DNA methyltransferase activity in acute myeloid leukemia.
Liu S, Liu Z, Xie Z, Pang J, Yu J, Lehmann E, Huynh L, Vukosavljevic T, Takeki M, Klisovic RB, Baiocchi RA, Blum W, Porcu P, Garzon R, Byrd JC, Perrotti D, Caligiuri MA, Chan KK, Wu LC, Marcucci G. Liu S, et al. Among authors: garzon r. Blood. 2008 Feb 15;111(4):2364-73. doi: 10.1182/blood-2007-08-110171. Epub 2007 Dec 14. Blood. 2008. PMID: 18083845 Free PMC article.
MicroRNA signatures associated with cytogenetics and prognosis in acute myeloid leukemia.
Garzon R, Volinia S, Liu CG, Fernandez-Cymering C, Palumbo T, Pichiorri F, Fabbri M, Coombes K, Alder H, Nakamura T, Flomenberg N, Marcucci G, Calin GA, Kornblau SM, Kantarjian H, Bloomfield CD, Andreeff M, Croce CM. Garzon R, et al. Blood. 2008 Mar 15;111(6):3183-9. doi: 10.1182/blood-2007-07-098749. Epub 2008 Jan 10. Blood. 2008. PMID: 18187662 Free PMC article.
MicroRNA expression in cytogenetically normal acute myeloid leukemia.
Marcucci G, Radmacher MD, Maharry K, Mrózek K, Ruppert AS, Paschka P, Vukosavljevic T, Whitman SP, Baldus CD, Langer C, Liu CG, Carroll AJ, Powell BL, Garzon R, Croce CM, Kolitz JE, Caligiuri MA, Larson RA, Bloomfield CD. Marcucci G, et al. Among authors: garzon r. N Engl J Med. 2008 May 1;358(18):1919-28. doi: 10.1056/NEJMoa074256. N Engl J Med. 2008. PMID: 18450603 Free article.
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.
Garzon R, Liu S, Fabbri M, Liu Z, Heaphy CE, Callegari E, Schwind S, Pang J, Yu J, Muthusamy N, Havelange V, Volinia S, Blum W, Rush LJ, Perrotti D, Andreeff M, Bloomfield CD, Byrd JC, Chan K, Wu LC, Croce CM, Marcucci G. Garzon R, et al. Blood. 2009 Jun 18;113(25):6411-8. doi: 10.1182/blood-2008-07-170589. Epub 2009 Feb 11. Blood. 2009. PMID: 19211935 Free PMC article.
MicroRNA 29b functions in acute myeloid leukemia.
Garzon R, Heaphy CE, Havelange V, Fabbri M, Volinia S, Tsao T, Zanesi N, Kornblau SM, Marcucci G, Calin GA, Andreeff M, Croce CM. Garzon R, et al. Blood. 2009 Dec 17;114(26):5331-41. doi: 10.1182/blood-2009-03-211938. Epub 2009 Oct 22. Blood. 2009. PMID: 19850741 Free PMC article.
miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts.
Eiring AM, Harb JG, Neviani P, Garton C, Oaks JJ, Spizzo R, Liu S, Schwind S, Santhanam R, Hickey CJ, Becker H, Chandler JC, Andino R, Cortes J, Hokland P, Huettner CS, Bhatia R, Roy DC, Liebhaber SA, Caligiuri MA, Marcucci G, Garzon R, Croce CM, Calin GA, Perrotti D. Eiring AM, et al. Among authors: garzon r. Cell. 2010 Mar 5;140(5):652-65. doi: 10.1016/j.cell.2010.01.007. Cell. 2010. PMID: 20211135 Free PMC article.
Sp1/NFkappaB/HDAC/miR-29b regulatory network in KIT-driven myeloid leukemia.
Liu S, Wu LC, Pang J, Santhanam R, Schwind S, Wu YZ, Hickey CJ, Yu J, Becker H, Maharry K, Radmacher MD, Li C, Whitman SP, Mishra A, Stauffer N, Eiring AM, Briesewitz R, Baiocchi RA, Chan KK, Paschka P, Caligiuri MA, Byrd JC, Croce CM, Bloomfield CD, Perrotti D, Garzon R, Marcucci G. Liu S, et al. Among authors: garzon r. Cancer Cell. 2010 Apr 13;17(4):333-47. doi: 10.1016/j.ccr.2010.03.008. Cancer Cell. 2010. PMID: 20385359 Free PMC article.
210 results