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Molecular pathogenesis of Parkinson disease: insights from genetic studies.
Gasser T. Gasser T. Expert Rev Mol Med. 2009 Jul 27;11:e22. doi: 10.1017/S1462399409001148. Expert Rev Mol Med. 2009. PMID: 19631006 Review.
A polymorphism in the intronic region of the IL-1alpha gene and the risk for Parkinson's disease.
Dodel RC, Lohmüller F, Du Y, Eastwood B, Gocke P, Oertel WH, Gasser T. Dodel RC, et al. Among authors: gasser t. Neurology. 2001 Apr 10;56(7):982-3. doi: 10.1212/wnl.56.7.982. Neurology. 2001. PMID: 11294947 No abstract available.
Molecular genetics of Parkinson's disease.
Gasser T. Gasser T. Adv Neurol. 2001;86:23-32. Adv Neurol. 2001. PMID: 11553982 Review.
The PARK8 locus in autosomal dominant parkinsonism: confirmation of linkage and further delineation of the disease-containing interval.
Zimprich A, Müller-Myhsok B, Farrer M, Leitner P, Sharma M, Hulihan M, Lockhart P, Strongosky A, Kachergus J, Calne DB, Stoessl J, Uitti RJ, Pfeiffer RF, Trenkwalder C, Homann N, Ott E, Wenzel K, Asmus F, Hardy J, Wszolek Z, Gasser T. Zimprich A, et al. Among authors: gasser t. Am J Hum Genet. 2004 Jan;74(1):11-9. doi: 10.1086/380647. Epub 2003 Dec 19. Am J Hum Genet. 2004. PMID: 14691730 Free PMC article.
Lack of association between the interleukin-1 alpha (-889) polymorphism and early-onset Parkinson's disease.
Möller JC, Depboylu C, Kölsch H, Lohmüller F, Bandmann O, Gocke P, Du Y, Paus S, Wüllner U, Gasser T, Oertel WH, Klockgether T, Dodel RC. Möller JC, et al. Among authors: gasser t. Neurosci Lett. 2004 Apr 15;359(3):195-7. doi: 10.1016/j.neulet.2004.01.058. Neurosci Lett. 2004. PMID: 15050696 Clinical Trial.

Recently, we detected an associated risk in a subgroup of PD patients with a disease onset < 50 years and a C to T transition in the IL-1alpha promoter (-889). ...We conclude that the C/T polymorphism in the IL-1alpha promoter region at -889 does not increase the

Recently, we detected an associated risk in a subgroup of PD patients with a disease onset < 50 years and a C to T transition in t

PARK11 is not linked with Parkinson's disease in European families.
Prestel J, Sharma M, Leitner P, Zimprich A, Vaughan JR, Dürr A, Bonifati V, De Michele G, Hanagasi HA, Farrer M, Hofer A, Asmus F, Volpe G, Meco G, Brice A, Wood NW, Müller-Myhsok B, Gasser T; European Consortium on Genetic Susceptibility in Parkinson's Disease (GSPD). Prestel J, et al. Among authors: gasser t. Eur J Hum Genet. 2005 Feb;13(2):193-7. doi: 10.1038/sj.ejhg.5201317. Eur J Hum Genet. 2005. PMID: 15523496
Mutations in LRRK2 cause autosomal-dominant parkinsonism with pleomorphic pathology.
Zimprich A, Biskup S, Leitner P, Lichtner P, Farrer M, Lincoln S, Kachergus J, Hulihan M, Uitti RJ, Calne DB, Stoessl AJ, Pfeiffer RF, Patenge N, Carbajal IC, Vieregge P, Asmus F, Müller-Myhsok B, Dickson DW, Meitinger T, Strom TM, Wszolek ZK, Gasser T. Zimprich A, et al. Among authors: gasser t. Neuron. 2004 Nov 18;44(4):601-7. doi: 10.1016/j.neuron.2004.11.005. Neuron. 2004. PMID: 15541309
The role of alpha-synuclein gene multiplications in early-onset Parkinson's disease and dementia with Lewy bodies.
Hofer A, Berg D, Asmus F, Niwar M, Ransmayr G, Riemenschneider M, Bonelli SB, Steffelbauer M, Ceballos-Baumann A, Haussermann P, Behnke S, Krüger R, Prestel J, Sharma M, Zimprich A, Riess O, Gasser T. Hofer A, et al. Among authors: gasser t. J Neural Transm (Vienna). 2005 Sep;112(9):1249-54. doi: 10.1007/s00702-004-0263-3. Epub 2004 Dec 29. J Neural Transm (Vienna). 2005. PMID: 15622440
New aspects of genetic contributions to Parkinson's disease.
Hofer A, Gasser T. Hofer A, et al. Among authors: gasser t. J Mol Neurosci. 2004;24(3):417-24. doi: 10.1385/JMN:24:3:417. J Mol Neurosci. 2004. PMID: 15655263 Review.
Multiple regions of alpha-synuclein are associated with Parkinson's disease.
Mueller JC, Fuchs J, Hofer A, Zimprich A, Lichtner P, Illig T, Berg D, Wüllner U, Meitinger T, Gasser T. Mueller JC, et al. Among authors: gasser t. Ann Neurol. 2005 Apr;57(4):535-41. doi: 10.1002/ana.20438. Ann Neurol. 2005. PMID: 15786467
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