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2009 3
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2012 5
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2017 2
2019 3
2020 2
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Adaptation of iron requirement to hypoxic conditions at high altitude.
Gassmann M, Muckenthaler MU. Gassmann M, et al. J Appl Physiol (1985). 2015 Dec 15;119(12):1432-40. doi: 10.1152/japplphysiol.00248.2015. Epub 2015 Jul 16. J Appl Physiol (1985). 2015. PMID: 26183475 Free article. Review.
Adequate acclimatization time to enable adjustment to hypoxic conditions is one of the most important aspects for mountaineers ascending to high altitude. ...As recently observed in sojourners at high altitude, however, iron uptake may be hampered by reduced appetit …
Adequate acclimatization time to enable adjustment to hypoxic conditions is one of the most important aspects for mountaineers ascending to …
High-Altitude Cognitive Impairment Is Prevented by Enriched Environment Including Exercise via VEGF Signaling.
Koester-Hegmann C, Bengoetxea H, Kosenkov D, Thiersch M, Haider T, Gassmann M, Schneider Gasser EM. Koester-Hegmann C, et al. Among authors: Gassmann M. Front Cell Neurosci. 2019 Jan 10;12:532. doi: 10.3389/fncel.2018.00532. eCollection 2018. Front Cell Neurosci. 2019. PMID: 30687018 Free PMC article.
Exposure to hypobaric hypoxia at high altitude (above 2500 m asl) causes cognitive impairment, mostly attributed to changes in brain perfusion and consequently neuronal death. ...We conclude that EE-mediated VEGF signaling is neuroprotective and essential for the maintenan …
Exposure to hypobaric hypoxia at high altitude (above 2500 m asl) causes cognitive impairment, mostly attributed to changes in brain …
Evaluation of Acute Mountain Sickness by Unsedated Transnasal Esophagogastroduodenoscopy at High Altitude.
Fruehauf H, Vavricka SR, Lutz TA, Gassmann M, Wojtal KA, Erb A, Maggiorini M, Schwizer W, Fried M, Fox M, Goetze O, Greuter T. Fruehauf H, et al. Among authors: Gassmann M. Clin Gastroenterol Hepatol. 2019 Nov 25:S1542-3565(19)31324-2. doi: 10.1016/j.cgh.2019.11.036. Online ahead of print. Clin Gastroenterol Hepatol. 2019. PMID: 31778804
BACKGROUND & AIMS: It is not clear how rapid ascent to a high altitude causes the gastrointestinal symptoms of acute mountain sickness (AMS). ...RESULTS: The follow-up endoscopy at high altitude was performed in 19 of 25 patients on day 2 and in 23 of 25 patient …
BACKGROUND & AIMS: It is not clear how rapid ascent to a high altitude causes the gastrointestinal symptoms of acute mountain sic …
The increase in hemoglobin concentration with altitude varies among human populations.
Gassmann M, Mairbäurl H, Livshits L, Seide S, Hackbusch M, Malczyk M, Kraut S, Gassmann NN, Weissmann N, Muckenthaler MU. Gassmann M, et al. Among authors: Gassmann NN. Ann N Y Acad Sci. 2019 Aug;1450(1):204-220. doi: 10.1111/nyas.14136. Epub 2019 Jun 30. Ann N Y Acad Sci. 2019. PMID: 31257609
Decreased oxygen availability at high altitude requires physiological adjustments allowing for adequate tissue oxygenation. One such mechanism is a slow increase in the hemoglobin concentration ([Hb]) resulting in elevated [Hb] in high-altitude residents. Diagnosis …
Decreased oxygen availability at high altitude requires physiological adjustments allowing for adequate tissue oxygenation. One such …
Red blood cell volume and the capacity for exercise at moderate to high altitude.
Jacobs RA, Lundby C, Robach P, Gassmann M. Jacobs RA, et al. Among authors: Gassmann M. Sports Med. 2012 Aug 1;42(8):643-63. doi: 10.1007/BF03262286. Sports Med. 2012. PMID: 22741918 Review.
Maximal exercise tests are often performed in hypoxic conditions following some form of RCV manipulation in an attempt to elucidate oxygen transport limitations at moderate to high altitudes. ...Adding to the uncertainty regarding the importance of RCV at high altitude
Maximal exercise tests are often performed in hypoxic conditions following some form of RCV manipulation in an attempt to elucidate oxygen t …
Hypoxia: adapting to high altitude by mutating EPAS-1, the gene encoding HIF-2α.
van Patot MC, Gassmann M. van Patot MC, et al. Among authors: Gassmann M. High Alt Med Biol. 2011 Summer;12(2):157-67. doi: 10.1089/ham.2010.1099. High Alt Med Biol. 2011. PMID: 21718164 Review.
Living at high altitude is demanding and thus drives adaptational mechanisms. The Tibetan population has had a longer evolutionary period to adapt to high altitude than other mountain populations such as Andeans. As a result, some Tibetans living at high altitude
Living at high altitude is demanding and thus drives adaptational mechanisms. The Tibetan population has had a longer evolutionary pe …
High altitude training of dogs results in elevated erythropoietin and endothelin-1 serum levels.
Glaus TM, Grenacher B, Koch D, Reiner B, Gassmann M. Glaus TM, et al. Among authors: Gassmann M. Comp Biochem Physiol A Mol Integr Physiol. 2004 Jul;138(3):355-61. doi: 10.1016/j.cbpb.2004.05.008. Comp Biochem Physiol A Mol Integr Physiol. 2004. PMID: 15313491
Despite moderate to marked hypoxemia at these altitudes, erythrocytosis does not develop. To study humoral mechanisms of acclimatisation to high altitude, erythropoietin (EPO), endothelin-1 (ET-1), big endothelin (Big-ET) and vascular endothelial growth factor (VEGF …
Despite moderate to marked hypoxemia at these altitudes, erythrocytosis does not develop. To study humoral mechanisms of acclimatisat …
The hypoxic placenta.
van Patot MC, Ebensperger G, Gassmann M, Llanos AJ. van Patot MC, et al. Among authors: Gassmann M. High Alt Med Biol. 2012 Sep;13(3):176-84. doi: 10.1089/ham.2012.1046. High Alt Med Biol. 2012. PMID: 22994517 Free article. Review.
Reduced cancer mortality at high altitude: The role of glucose, lipids, iron and physical activity.
Thiersch M, Swenson ER, Haider T, Gassmann M. Thiersch M, et al. Among authors: Gassmann M. Exp Cell Res. 2017 Jul 15;356(2):209-216. doi: 10.1016/j.yexcr.2017.03.048. Epub 2017 Mar 23. Exp Cell Res. 2017. PMID: 28344053 Review.
Residency at high altitude (HA) demands adaptation to challenging environmental conditions with hypobaric hypoxia being the most important one. ...In this review we discuss tumor formation as a concept of competition between healthy and cancer cells with improved fitness - …
Residency at high altitude (HA) demands adaptation to challenging environmental conditions with hypobaric hypoxia being the most impo …
Timing the arrival at 2340 m altitude for aerobic performance.
Schuler B, Thomsen JJ, Gassmann M, Lundby C. Schuler B, et al. Among authors: Gassmann M. Scand J Med Sci Sports. 2007 Oct;17(5):588-94. doi: 10.1111/j.1600-0838.2006.00611.x. Epub 2007 Feb 19. Scand J Med Sci Sports. 2007. PMID: 17316377
This study tested the hypothesis that maximal oxygen uptake (VO(2max)) and performance increase upon altitude acclimatization at moderate altitude. ...These data suggest that endurance athletes competing at altitudes around 2340 m should expose themselves to …
This study tested the hypothesis that maximal oxygen uptake (VO(2max)) and performance increase upon altitude acclimatization at mode …
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