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Regulatory mechanisms in T cell receptor signalling.
Gaud G, Lesourne R, Love PE. Gaud G, et al. Nat Rev Immunol. 2018 Aug;18(8):485-497. doi: 10.1038/s41577-018-0020-8. Nat Rev Immunol. 2018. PMID: 29789755 Review.
A Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to Neuroinflammation.
Kassem S, Gaud G, Bernard I, Benamar M, Dejean AS, Liblau R, Fournié GJ, Colacios C, Malissen B, Saoudi A. Kassem S, et al. Among authors: gaud g. PLoS Genet. 2016 Jul 20;12(7):e1006185. doi: 10.1371/journal.pgen.1006185. eCollection 2016 Jul. PLoS Genet. 2016. PMID: 27438086 Free PMC article.
An Epistatic Interaction between Themis1 and Vav1 Modulates Regulatory T Cell Function and Inflammatory Bowel Disease Development.
Pedros C, Gaud G, Bernard I, Kassem S, Chabod M, Lagrange D, Andréoletti O, Dejean AS, Lesourne R, Fournié GJ, Saoudi A. Pedros C, et al. Among authors: gaud g. J Immunol. 2015 Aug 15;195(4):1608-16. doi: 10.4049/jimmunol.1402562. Epub 2015 Jul 10. J Immunol. 2015. PMID: 26163585 Free article.
The costimulatory molecule CD226 signals through VAV1 to amplify TCR signals and promote IL-17 production by CD4+ T cells.
Gaud G, Roncagalli R, Chaoui K, Bernard I, Familiades J, Colacios C, Kassem S, Monsarrat B, Burlet-Schiltz O, de Peredo AG, Malissen B, Saoudi A. Gaud G, et al. Sci Signal. 2018 Jul 10;11(538):eaar3083. doi: 10.1126/scisignal.aar3083. Sci Signal. 2018. PMID: 29991650
Rho-GTPases as key regulators of T lymphocyte biology.
Saoudi A, Kassem S, Dejean A, Gaud G. Saoudi A, et al. Among authors: gaud g. Small GTPases. 2014;5:e28208. doi: 10.4161/sgtp.28208. Epub 2014 May 8. Small GTPases. 2014. PMID: 24825161 Free PMC article. Review.
Inhibition of cervical cancer cell growth by human papillomavirus virus-like particles packaged with human papillomavirus oncoprotein short hairpin RNAs.
Bousarghin L, Touze A, Gaud G, Iochmann S, Alvarez E, Reverdiau P, Gaitan J, Jourdan ML, Sizaret PY, Coursaget PL. Bousarghin L, et al. Among authors: gaud g. Mol Cancer Ther. 2009 Feb;8(2):357-65. doi: 10.1158/1535-7163.MCT-08-0626. Epub 2009 Jan 27. Mol Cancer Ther. 2009. PMID: 19174559
TFPI-2 silencing increases tumour progression and promotes metalloproteinase 1 and 3 induction through tumour-stromal cell interactions.
Gaud G, Iochmann S, Guillon-Munos A, Brillet B, Petiot S, Seigneuret F, Touzé A, Heuzé-Vourc'h N, Courty Y, Lerondel S, Gruel Y, Reverdiau P. Gaud G, et al. J Cell Mol Med. 2011 Feb;15(2):196-208. doi: 10.1111/j.1582-4934.2009.00989.x. J Cell Mol Med. 2011. PMID: 20015200 Free PMC article.
EVER2 protein binds TRADD to promote TNF-α-induced apoptosis.
Gaud G, Guillemot D, Jacob Y, Favre M, Vuillier F. Gaud G, et al. Cell Death Dis. 2013 Feb 21;4(2):e499. doi: 10.1038/cddis.2013.27. Cell Death Dis. 2013. PMID: 23429285 Free PMC article.
Transient RNA silencing of tissue factor pathway inhibitor-2 modulates lung cancer cell invasion.
Iochmann S, Bléchet C, Chabot V, Saulnier A, Amini A, Gaud G, Gruel Y, Reverdiau P. Iochmann S, et al. Among authors: gaud g. Clin Exp Metastasis. 2009;26(5):457-67. doi: 10.1007/s10585-009-9245-z. Epub 2009 Mar 7. Clin Exp Metastasis. 2009. PMID: 19267203
Loss of the HPV-infection resistance EVER2 protein impairs NF-κB signaling pathways in keratinocytes.
Vuillier F, Gaud G, Guillemot D, Commere PH, Pons C, Favre M. Vuillier F, et al. Among authors: gaud g. PLoS One. 2014 Feb 19;9(2):e89479. doi: 10.1371/journal.pone.0089479. eCollection 2014. PLoS One. 2014. PMID: 24586810 Free PMC article.
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