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Page 1
A major lung cancer susceptibility locus maps to chromosome 6q23-25.
Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Wiest JS, Fain P, Schwartz AG, You M, Franklin W, Klein C, Gazdar A, Rothschild H, Mandal D, Coons T, Slusser J, Lee J, Gaba C, Kupert E, Perez A, Zhou X, Zeng D, Liu Q, Zhang Q, Seminara D, Minna J, Anderson MW. Bailey-Wilson JE, et al. Among authors: gazdar a. Am J Hum Genet. 2004 Sep;75(3):460-74. doi: 10.1086/423857. Epub 2004 Jul 21. Am J Hum Genet. 2004. PMID: 15272417 Free PMC article.
A susceptibility locus on chromosome 6q greatly increases lung cancer risk among light and never smokers.
Amos CI, Pinney SM, Li Y, Kupert E, Lee J, de Andrade MA, Yang P, Schwartz AG, Fain PR, Gazdar A, Minna J, Wiest JS, Zeng D, Rothschild H, Mandal D, You M, Coons T, Gaba C, Bailey-Wilson JE, Anderson MW. Amos CI, et al. Among authors: gazdar a. Cancer Res. 2010 Mar 15;70(6):2359-67. doi: 10.1158/0008-5472.CAN-09-3096. Epub 2010 Mar 9. Cancer Res. 2010. PMID: 20215501 Free PMC article.
Familial aggregation of common sequence variants on 15q24-25.1 in lung cancer.
Liu P, Vikis HG, Wang D, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Gazdar A, Gaba C, Rothschild H, Mandal D, Coons T, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Wu X, Spitz MR, Eisen T, Houlston RS, Amos CI, Anderson MW, You M. Liu P, et al. Among authors: gazdar a. J Natl Cancer Inst. 2008 Sep 17;100(18):1326-30. doi: 10.1093/jnci/djn268. Epub 2008 Sep 9. J Natl Cancer Inst. 2008. PMID: 18780872 Free PMC article.
Fine mapping of chromosome 6q23-25 region in familial lung cancer families reveals RGS17 as a likely candidate gene.
You M, Wang D, Liu P, Vikis H, James M, Lu Y, Wang Y, Wang M, Chen Q, Jia D, Liu Y, Wen W, Yang P, Sun Z, Pinney SM, Zheng W, Shu XO, Long J, Gao YT, Xiang YB, Chow WH, Rothman N, Petersen GM, de Andrade M, Wu Y, Cunningham JM, Wiest JS, Fain PR, Schwartz AG, Girard L, Gazdar A, Gaba C, Rothschild H, Mandal D, Coons T, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Amos CI, Anderson MW. You M, et al. Among authors: gazdar a. Clin Cancer Res. 2009 Apr 15;15(8):2666-74. doi: 10.1158/1078-0432.CCR-08-2335. Epub 2009 Apr 7. Clin Cancer Res. 2009. PMID: 19351763 Free PMC article.
Haplotype and cell proliferation analyses of candidate lung cancer susceptibility genes on chromosome 15q24-25.1.
Liu Y, Liu P, Wen W, James MA, Wang Y, Bailey-Wilson JE, Amos CI, Pinney SM, Yang P, de Andrade M, Petersen GM, Wiest JS, Fain PR, Schwartz AG, Gazdar A, Gaba C, Rothschild H, Mandal D, Kupert E, Lee J, Seminara D, Minna J, Anderson MW, You M. Liu Y, et al. Among authors: gazdar a. Cancer Res. 2009 Oct 1;69(19):7844-50. doi: 10.1158/0008-5472.CAN-09-1833. Epub 2009 Sep 29. Cancer Res. 2009. PMID: 19789337 Free PMC article.
Cumulative effect of multiple loci on genetic susceptibility to familial lung cancer.
Liu P, Vikis HG, Lu Y, Wang Y, Schwartz AG, Pinney SM, Yang P, de Andrade M, Gazdar A, Gaba C, Mandal D, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Amos CI, Anderson MW, You M. Liu P, et al. Among authors: gazdar a. Cancer Epidemiol Biomarkers Prev. 2010 Feb;19(2):517-24. doi: 10.1158/1055-9965.EPI-09-0791. Cancer Epidemiol Biomarkers Prev. 2010. PMID: 20142248 Free PMC article.
EGFR-T790M is a rare lung cancer susceptibility allele with enhanced kinase activity.
Vikis H, Sato M, James M, Wang D, Wang Y, Wang M, Jia D, Liu Y, Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Yang P, Wiest JS, Fain PR, Schwartz AG, Gazdar A, Gaba C, Rothschild H, Mandal D, Kupert E, Seminara D, Viswanathan A, Govindan R, Minna J, Anderson MW, You M. Vikis H, et al. Among authors: gazdar a. Cancer Res. 2007 May 15;67(10):4665-70. doi: 10.1158/0008-5472.CAN-07-0217. Cancer Res. 2007. PMID: 17510392 Free PMC article.
A second genetic variant on chromosome 15q24-25.1 associates with lung cancer.
Liu P, Yang P, Wu X, Vikis HG, Lu Y, Wang Y, Schwartz AG, Pinney SM, de Andrade M, Gazdar A, Gaba C, Mandal D, Lee J, Kupert E, Seminara D, Minna J, Bailey-Wilson JE, Spitz M, Amos CI, Anderson MW, You M. Liu P, et al. Among authors: gazdar a. Cancer Res. 2010 Apr 15;70(8):3128-35. doi: 10.1158/0008-5472.CAN-09-3583. Cancer Res. 2010. PMID: 20395203 Free PMC article.
Identification of a novel tumor suppressor gene p34 on human chromosome 6q25.1.
Wang M, Vikis HG, Wang Y, Jia D, Wang D, Bierut LJ, Bailey-Wilson JE, Amos CI, Pinney SM, Petersen GM, de Andrade M, Yang P, Wiest JS, Fain PR, Schwartz AG, Gazdar A, Minna J, Gaba C, Rothschild H, Mandal D, Kupert E, Seminara D, Liu Y, Viswanathan A, Govindan R, Anderson MW, You M. Wang M, et al. Among authors: gazdar a. Cancer Res. 2007 Jan 1;67(1):93-9. doi: 10.1158/0008-5472.CAN-06-2723. Cancer Res. 2007. PMID: 17210687 Free PMC article.
Risk for nicotine dependence and lung cancer is conferred by mRNA expression levels and amino acid change in CHRNA5.
Wang JC, Cruchaga C, Saccone NL, Bertelsen S, Liu P, Budde JP, Duan W, Fox L, Grucza RA, Kern J, Mayo K, Reyes O, Rice J, Saccone SF, Spiegel N, Steinbach JH, Stitzel JA, Anderson MW, You M, Stevens VL, Bierut LJ, Goate AM; COGEND collaborators and GELCC collaborators. Wang JC, et al. Hum Mol Genet. 2009 Aug 15;18(16):3125-35. doi: 10.1093/hmg/ddp231. Epub 2009 May 14. Hum Mol Genet. 2009. PMID: 19443489 Free PMC article.
784 results