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Year Number of Results
1994 1
1995 2
1996 3
1997 3
1998 2
1999 3
2000 1
2001 1
2002 3
2003 5
2004 4
2005 2
2006 1
2008 4
2009 2
2010 4
2011 4
2012 5
2013 7
2014 8
2015 7
2016 5
2017 3
2018 1
2019 1
2020 5
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94 results

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Page 1
Immunotherapy with GcMAF revisited - A critical overview of the research of Nobuto Yamamoto.
Albracht SP. Albracht SP. Cancer Treat Res Commun. 2022;31:100537. doi: 10.1016/j.ctarc.2022.100537. Epub 2022 Feb 18. Cancer Treat Res Commun. 2022. PMID: 35217488 Free article. Review.
This overview describes the research of Nobutu Yamamoto (Philadelphia) concerning immunotherapy with GcMAF for patients with cancer and for patients infected with pathogenic envelope viruses. GcMAF (Group-specific component Macrophage-Activating Fac …
This overview describes the research of Nobutu Yamamoto (Philadelphia) concerning immunotherapy with GcMAF for patients with cancer a …
Analysis of the Biological Properties of Blood Plasma Protein with GcMAF Functional Activity.
Dolgova EV, Kirikovich SS, Levites EV, Ruzanova VS, Proskurina AS, Ritter GS, Taranov OS, Varaksin NA, Ryabicheva TG, Leplina OY, Ostanin AA, Chernykh ER, Bogachev SS. Dolgova EV, et al. Int J Mol Sci. 2022 Jul 22;23(15):8075. doi: 10.3390/ijms23158075. Int J Mol Sci. 2022. PMID: 35897653 Free PMC article.
The main problem related to the studies focusing on group-specific component protein-derived macrophage-activating factor (GcMAF) is the lack of clarity about changes occurring in different types of macrophages and related changes in their prope …
The main problem related to the studies focusing on group-specific component protein-derived macrophage-activating f …
Simple method for large-scale production of macrophage activating factor GcMAF.
Nabeshima Y, Abe C, Kawauchi T, Hiroi T, Uto Y, Nabeshima YI. Nabeshima Y, et al. Sci Rep. 2020 Nov 5;10(1):19122. doi: 10.1038/s41598-020-75571-y. Sci Rep. 2020. PMID: 33154460 Free PMC article.
Human group-specific component protein (Gc protein) is a multifunctional serum protein which has three common allelic variants, Gc1F, Gc1S and Gc2 in humans. Gc1 contains an O-linked trisaccharide [sialic acid-galactose-N-acetylgalactosamine (GalNAc)] on the …
Human group-specific component protein (Gc protein) is a multifunctional serum protein which has three common allelic v …
Gc protein (vitamin D-binding protein): Gc genotyping and GcMAF precursor activity.
Nagasawa H, Uto Y, Sasaki H, Okamura N, Murakami A, Kubo S, Kirk KL, Hori H. Nagasawa H, et al. Anticancer Res. 2005 Nov-Dec;25(6A):3689-95. Anticancer Res. 2005. PMID: 16302727 Free article. Review.
The Gc protein (human group-specific component (Gc), a vitamin D-binding protein or Gc globulin), has important physiological functions that include involvement in vitamin D transport and storage, scavenging of extracellular G-acti …
The Gc protein (human group-specific component (Gc), a vitamin D-binding protein or Gc globulin), has imp …
Case Report: GcMAF Treatment in a Patient with Multiple Sclerosis.
Inui T, Katsuura G, Kubo K, Kuchiike D, Chenery L, Uto Y, Nishikata T, Mette M. Inui T, et al. Anticancer Res. 2016 Jul;36(7):3771-4. Anticancer Res. 2016. PMID: 27354653
BACKGROUND/AIM: Gc protein-derived macrophage-activating factor (GcMAF) has various functions as an immune modulator, such as macrophage activation, anti-angiogenic activity and anti-tumor activity. ...Thus, GcMAF-based immunothera …
BACKGROUND/AIM: Gc protein-derived macrophage-activating factor (GcMAF) has various functions as an immun …
Degalactosylated/desialylated human serum containing GcMAF induces macrophage phagocytic activity and in vivo antitumor activity.
Kuchiike D, Uto Y, Mukai H, Ishiyama N, Abe C, Tanaka D, Kawai T, Kubo K, Mette M, Inui T, Endo Y, Hori H. Kuchiike D, et al. Anticancer Res. 2013 Jul;33(7):2881-5. Anticancer Res. 2013. PMID: 23780974
BACKGROUND: The group-specific component protein-derived macrophage-activating factor (GcMAF) has various biological activities, such as macrophage activation and antitumor activity. ...In this study, despite the complicated purification …
BACKGROUND: The group-specific component protein-derived macrophage-activating factor (GcMAF) has various …
Investigation of the Protective Effect for GcMAF by a Glycosidase Inhibitor and the Glycan Structure of Gc Protein.
Kanie Y, Maegawa Y, Wei Y, Kanie O. Kanie Y, et al. Molecules. 2023 Feb 6;28(4):1570. doi: 10.3390/molecules28041570. Molecules. 2023. PMID: 36838558 Free PMC article.
O-linked alpha-N-acetylgalactosamine (alpha-GalNAc) in the Gc protein is essential for macrophage activation; thus, the GalNAc-attached form of Gc protein is called Gc macrophage activating factor (GcMAF). ...Upon hydrolysis of alp …
O-linked alpha-N-acetylgalactosamine (alpha-GalNAc) in the Gc protein is essential for macrophage activation; thus, the GalNAc …
Gc protein-derived macrophage activating factor (GcMAF): isoelectric focusing pattern and tumoricidal activity.
Mohamad SB, Nagasawa H, Sasaki H, Uto Y, Nakagawa Y, Kawashima K, Hori H. Mohamad SB, et al. Anticancer Res. 2003 Nov-Dec;23(6a):4451-7. Anticancer Res. 2003. PMID: 14666733
BACKGROUND: Gc protein is the precursor for Gc protein-derived macrophage activating factor (GcMAF), with three phenotypes: Gc1f, Gc1s and Gc2, based on its electrophoretic mobility. ...CONCLUSION: The difference of isoelectric focusing m …
BACKGROUND: Gc protein is the precursor for Gc protein-derived macrophage activating factor (GcMAF …
94 results