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Nonessential amino acid metabolism in breast cancer.
Geck RC, Toker A. Geck RC, et al. Adv Biol Regul. 2016 Sep;62:11-17. doi: 10.1016/j.jbior.2016.01.001. Epub 2016 Jan 21. Adv Biol Regul. 2016. PMID: 26838061 Review.
Oncogenic PI3K promotes methionine dependency in breast cancer cells through the cystine-glutamate antiporter xCT.
Lien EC, Ghisolfi L, Geck RC, Asara JM, Toker A. Lien EC, et al. Among authors: geck rc. Sci Signal. 2017 Dec 19;10(510):eaao6604. doi: 10.1126/scisignal.aao6604. Sci Signal. 2017. PMID: 29259101 Free PMC article.
Inhibition of the polyamine synthesis enzyme ornithine decarboxylase sensitizes triple-negative breast cancer cells to cytotoxic chemotherapy.
Geck RC, Foley JR, Murray Stewart T, Asara JM, Casero RA Jr, Toker A. Geck RC, et al. J Biol Chem. 2020 May 8;295(19):6263-6277. doi: 10.1074/jbc.RA119.012376. Epub 2020 Mar 5. J Biol Chem. 2020. PMID: 32139506 Free PMC article.
The INPP4B Tumor Suppressor Modulates EGFR Trafficking and Promotes Triple-Negative Breast Cancer.
Liu H, Paddock MN, Wang H, Murphy CJ, Geck RC, Navarro AJ, Wulf GM, Elemento O, Haucke V, Cantley LC, Toker A. Liu H, et al. Among authors: geck rc. Cancer Discov. 2020 Aug;10(8):1226-1239. doi: 10.1158/2159-8290.CD-19-1262. Epub 2020 Jun 8. Cancer Discov. 2020. PMID: 32513774 Free article.
Metabolic pathway alterations in microvascular endothelial cells in response to hypoxia.
Cohen EB, Geck RC, Toker A. Cohen EB, et al. Among authors: geck rc. PLoS One. 2020 Jul 9;15(7):e0232072. doi: 10.1371/journal.pone.0232072. eCollection 2020. PLoS One. 2020. PMID: 32645038 Free PMC article.
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