Gehrke I - Search Results

1

Bone marrow stromal cell-derived vascular endothelial growth factor (VEGF) rather than chronic lymphocytic leukemia (CLL) cell-derived VEGF is essential for the apoptotic resistance of cultured CLL cells.

Gehrke I, Gandhirajan RK, Poll-Wolbeck SJ, Hallek M, Kreuzer KA. Gehrke I, et al. Mol Med. 2011;17(7-8):619-27. doi: 10.2119/molmed.2010.00210. Epub 2011 Apr 14. Mol Med. 2011. PMID: 21519633 Free PMC article.

2

Wnt/β-catenin/LEF-1 signaling in chronic lymphocytic leukemia (CLL): a target for current and potential therapeutic options.

Gandhirajan RK, Poll-Wolbeck SJ, Gehrke I, Kreuzer KA. Gandhirajan RK, et al. Among authors: gehrke i. Curr Cancer Drug Targets. 2010 Nov;10(7):716-27. doi: 10.2174/156800910793605794. Curr Cancer Drug Targets. 2010. PMID: 20578984 Review.

3

Small molecule inhibitors of Wnt/beta-catenin/lef-1 signaling induces apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo.

Gandhirajan RK, Staib PA, Minke K, Gehrke I, Plickert G, Schlösser A, Schmitt EK, Hallek M, Kreuzer KA. Gandhirajan RK, et al. Among authors: gehrke i. Neoplasia. 2010 Apr;12(4):326-35. doi: 10.1593/neo.91972. Neoplasia. 2010. PMID: 20360943 Free PMC article.

4

The vascular endothelial growth factor receptor tyrosine kinase inhibitors vatalanib and pazopanib potently induce apoptosis in chronic lymphocytic leukemia cells in vitro and in vivo.

Paesler J, Gehrke I, Gandhirajan RK, Filipovich A, Hertweck M, Erdfelder F, Uhrmacher S, Poll-Wolbeck SJ, Hallek M, Kreuzer KA. Paesler J, et al. Among authors: gehrke i. Clin Cancer Res. 2010 Jul 1;16(13):3390-8. doi: 10.1158/1078-0432.CCR-10-0232. Epub 2010 Jun 22. Clin Cancer Res. 2010. PMID: 20570929

5

Evidence for non-functional Dickkopf-1 (DKK-1) signaling in chronic lymphocytic leukemia (CLL).

Filipovich A, Gandhirajan RK, Gehrke I, Poll-Wolbeck SJ, Kreuzer KA. Filipovich A, et al. Among authors: gehrke i. Eur J Haematol. 2010 Oct;85(4):309-13. doi: 10.1111/j.1600-0609.2010.01494.x. Epub 2010 Aug 30. Eur J Haematol. 2010. PMID: 20618428

6

Nitric oxide-donating acetylsalicylic acid induces apoptosis in chronic lymphocytic leukemia cells and shows strong antitumor efficacy in vivo.

Razavi R, Gehrke I, Gandhirajan RK, Poll-Wolbeck SJ, Hallek M, Kreuzer KA. Razavi R, et al. Among authors: gehrke i. Clin Cancer Res. 2011 Jan 15;17(2):286-93. doi: 10.1158/1078-0432.CCR-10-1030. Epub 2010 Nov 19. Clin Cancer Res. 2011. PMID: 21097689

7

Use of the receptor tyrosine kinase-like orphan receptor 1 (ROR1) as a diagnostic tool in chronic lymphocytic leukemia (CLL).

Uhrmacher S, Schmidt C, Erdfelder F, Poll-Wolbeck SJ, Gehrke I, Hallek M, Kreuzer KA. Uhrmacher S, et al. Among authors: gehrke i. Leuk Res. 2011 Oct;35(10):1360-6. doi: 10.1016/j.leukres.2011.04.006. Epub 2011 Apr 30. Leuk Res. 2011. PMID: 21531460

8

Targeting the vascular endothelial growth factor in hematologic malignancies.

Paesler J, Gehrke I, Poll-Wolbeck SJ, Kreuzer KA. Paesler J, et al. Among authors: gehrke i. Eur J Haematol. 2012 Nov;89(5):373-84. doi: 10.1111/ejh.12009. Epub 2012 Sep 20. Eur J Haematol. 2012. PMID: 22928557 Review.

9

The Antineoplastic Effect of Nitric Oxide-Donating Acetylsalicylic Acid (NO-ASA) in Chronic Lymphocytic Leukemia (CLL) Cells is Highly Dependent on its Positional Isomerism.

Gehrke I, Razavi R, Poll-Wolbeck SJ, Berkessel A, Hallek M, Kreuzer KA. Gehrke I, et al. Ther Adv Hematol. 2011 Oct;2(5):279-89. doi: 10.1177/2040620711416272. Ther Adv Hematol. 2011. PMID: 23556096 Free PMC article.

10

Trichostatin A effectively induces apoptosis in chronic lymphocytic leukemia cells via inhibition of Wnt signaling and histone deacetylation.

Peiffer L, Poll-Wolbeck SJ, Flamme H, Gehrke I, Hallek M, Kreuzer KA. Peiffer L, et al. Among authors: gehrke i. J Cancer Res Clin Oncol. 2014 Aug;140(8):1283-93. doi: 10.1007/s00432-014-1689-0. Epub 2014 May 4. J Cancer Res Clin Oncol. 2014. PMID: 24793644

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