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Delivery of siRNA to the mouse lung via a functionalized lipopolyamine.
Polach KJ, Matar M, Rice J, Slobodkin G, Sparks J, Congo R, Rea-Ramsey A, McClure D, Brunhoeber E, Krampert M, Schuster A, Jahn-Hofmann K, John M, Vornlocher HP, Fewell JG, Anwer K, Geick A. Polach KJ, et al. Among authors: geick a. Mol Ther. 2012 Jan;20(1):91-100. doi: 10.1038/mt.2011.210. Epub 2011 Oct 11. Mol Ther. 2012. PMID: 21988874 Free PMC article.
Gene silencing by RNAi in mammalian cells.
John M, Geick A, Hadwiger P, Vornlocher HP, Heidenreich O. John M, et al. Among authors: geick a. Curr Protoc Mol Biol. 2003 May;Chapter 26:Unit 26.2. doi: 10.1002/0471142727.mb2602s62. Curr Protoc Mol Biol. 2003. PMID: 18265326
Hyperoxia causes angiopoietin 2-mediated acute lung injury and necrotic cell death.
Bhandari V, Choo-Wing R, Lee CG, Zhu Z, Nedrelow JH, Chupp GL, Zhang X, Matthay MA, Ware LB, Homer RJ, Lee PJ, Geick A, de Fougerolles AR, Elias JA. Bhandari V, et al. Among authors: geick a. Nat Med. 2006 Nov;12(11):1286-93. doi: 10.1038/nm1494. Epub 2006 Nov 5. Nat Med. 2006. PMID: 17086189 Free PMC article.
Therapeutic silencing of an endogenous gene by systemic administration of modified siRNAs.
Soutschek J, Akinc A, Bramlage B, Charisse K, Constien R, Donoghue M, Elbashir S, Geick A, Hadwiger P, Harborth J, John M, Kesavan V, Lavine G, Pandey RK, Racie T, Rajeev KG, Röhl I, Toudjarska I, Wang G, Wuschko S, Bumcrot D, Koteliansky V, Limmer S, Manoharan M, Vornlocher HP. Soutschek J, et al. Among authors: geick a. Nature. 2004 Nov 11;432(7014):173-8. doi: 10.1038/nature03121. Nature. 2004. PMID: 15538359 Free article.
Small interfering RNA targeting bcl-2 sensitizes malignant melanoma.
Wacheck V, Losert D, Günsberg P, Vornlocher HP, Hadwiger P, Geick A, Pehamberger H, Müller M, Jansen B. Wacheck V, et al. Among authors: geick a. Oligonucleotides. 2003;13(5):393-400. doi: 10.1089/154545703322617078. Oligonucleotides. 2003. PMID: 15000830
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