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Kininogen deficiency protects from ischemic neurodegeneration in mice by reducing thrombosis, blood-brain barrier damage, and inflammation.
Langhauser F, Göb E, Kraft P, Geis C, Schmitt J, Brede M, Göbel K, Helluy X, Pham M, Bendszus M, Jakob P, Stoll G, Meuth SG, Nieswandt B, McCrae KR, Kleinschnitz C. Langhauser F, et al. Among authors: geis c. Blood. 2012 Nov 8;120(19):4082-92. doi: 10.1182/blood-2012-06-440057. Epub 2012 Aug 30. Blood. 2012. PMID: 22936662 Free PMC article.
Blocking of plasma kallikrein ameliorates stroke by reducing thromboinflammation.
Göb E, Reymann S, Langhauser F, Schuhmann MK, Kraft P, Thielmann I, Göbel K, Brede M, Homola G, Solymosi L, Stoll G, Geis C, Meuth SG, Nieswandt B, Kleinschnitz C. Göb E, et al. Among authors: geis c. Ann Neurol. 2015 May;77(5):784-803. doi: 10.1002/ana.24380. Epub 2015 Mar 13. Ann Neurol. 2015. PMID: 25628066
NOX4 is an early initiator of neuropathic pain.
Geis C, Geuss E, Sommer C, Schmidt HH, Kleinschnitz C. Geis C, et al. Exp Neurol. 2017 Feb;288:94-103. doi: 10.1016/j.expneurol.2016.11.008. Epub 2016 Nov 14. Exp Neurol. 2017. PMID: 27856286
126 results