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Minor viral and host genetic polymorphisms can dramatically impact the biologic outcome of an epitope-specific CD8 T-cell response.
Geldmacher C, Metzler IS, Tovanabutra S, Asher TE, Gostick E, Ambrozak DR, Petrovas C, Schuetz A, Ngwenyama N, Kijak G, Maboko L, Hoelscher M, McCutchan F, Price DA, Douek DC, Koup RA. Geldmacher C, et al. Blood. 2009 Aug 20;114(8):1553-62. doi: 10.1182/blood-2009-02-206193. Epub 2009 Jun 19. Blood. 2009. PMID: 19542300 Free PMC article.
Differential association of programmed death-1 and CD57 with ex vivo survival of CD8+ T cells in HIV infection.
Petrovas C, Chaon B, Ambrozak DR, Price DA, Melenhorst JJ, Hill BJ, Geldmacher C, Casazza JP, Chattopadhyay PK, Roederer M, Douek DC, Mueller YM, Jacobson JM, Kulkarni V, Felber BK, Pavlakis GN, Katsikis PD, Koup RA. Petrovas C, et al. Among authors: geldmacher c. J Immunol. 2009 Jul 15;183(2):1120-32. doi: 10.4049/jimmunol.0900182. Epub 2009 Jun 29. J Immunol. 2009. PMID: 19564339 Free PMC article.
Viral and host factors associated with the HIV-1 viral load setpoint in adults from Mbeya Region, Tanzania.
Saathoff E, Pritsch M, Geldmacher C, Hoffmann O, Koehler RN, Maboko L, Maganga L, Geis S, McCutchan FE, Kijak GH, Kim JH, Arroyo MA, Gerhardt M, Tovanabutra S, Robb ML, Williamson C, Michael NL, Hoelscher M. Saathoff E, et al. Among authors: geldmacher c. J Acquir Immune Defic Syndr. 2010 Jul;54(3):324-30. doi: 10.1097/qai.0b013e3181cf30ba. J Acquir Immune Defic Syndr. 2010. PMID: 20632457 Free PMC article.
Preferential infection and depletion of Mycobacterium tuberculosis-specific CD4 T cells after HIV-1 infection.
Geldmacher C, Ngwenyama N, Schuetz A, Petrovas C, Reither K, Heeregrave EJ, Casazza JP, Ambrozak DR, Louder M, Ampofo W, Pollakis G, Hill B, Sanga E, Saathoff E, Maboko L, Roederer M, Paxton WA, Hoelscher M, Koup RA. Geldmacher C, et al. J Exp Med. 2010 Dec 20;207(13):2869-81. doi: 10.1084/jem.20100090. Epub 2010 Nov 29. J Exp Med. 2010. PMID: 21115690 Free PMC article.
73 results