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Pseudomonas aeruginosa: new insights into pathogenesis and host defenses.
Gellatly SL, Hancock RE. Gellatly SL, et al. Pathog Dis. 2013 Apr;67(3):159-73. doi: 10.1111/2049-632X.12033. Epub 2013 Mar 15. Pathog Dis. 2013. PMID: 23620179 Review.
Multifunctional cationic host defence peptides and their clinical applications.
Yeung AT, Gellatly SL, Hancock RE. Yeung AT, et al. Among authors: gellatly sl. Cell Mol Life Sci. 2011 Jul;68(13):2161-76. doi: 10.1007/s00018-011-0710-x. Epub 2011 May 15. Cell Mol Life Sci. 2011. PMID: 21573784 Review.
The sensor kinase PhoQ mediates virulence in Pseudomonas aeruginosa.
Gooderham WJ, Gellatly SL, Sanschagrin F, McPhee JB, Bains M, Cosseau C, Levesque RC, Hancock REW. Gooderham WJ, et al. Among authors: gellatly sl. Microbiology (Reading). 2009 Mar;155(Pt 3):699-711. doi: 10.1099/mic.0.024554-0. Microbiology (Reading). 2009. PMID: 19246741
The Pseudomonas aeruginosa PhoP-PhoQ two-component regulatory system is induced upon interaction with epithelial cells and controls cytotoxicity and inflammation.
Gellatly SL, Needham B, Madera L, Trent MS, Hancock RE. Gellatly SL, et al. Infect Immun. 2012 Sep;80(9):3122-31. doi: 10.1128/IAI.00382-12. Epub 2012 Jun 18. Infect Immun. 2012. PMID: 22710876 Free PMC article.
Novel roles for two-component regulatory systems in cytotoxicity and virulence-related properties in Pseudomonas aeruginosa.
Gellatly SL, Bains M, Breidenstein EBM, Strehmel J, Reffuveille F, Taylor PK, Yeung ATY, Overhage J, Hancock REW. Gellatly SL, et al. AIMS Microbiol. 2018 Mar 8;4(1):173-191. doi: 10.3934/microbiol.2018.1.173. eCollection 2018. AIMS Microbiol. 2018. PMID: 31294209 Free PMC article.
The Lon protease is essential for full virulence in Pseudomonas aeruginosa.
Breidenstein EB, Janot L, Strehmel J, Fernandez L, Taylor PK, Kukavica-Ibrulj I, Gellatly SL, Levesque RC, Overhage J, Hancock RE. Breidenstein EB, et al. Among authors: gellatly sl. PLoS One. 2012;7(11):e49123. doi: 10.1371/journal.pone.0049123. Epub 2012 Nov 7. PLoS One. 2012. PMID: 23145092 Free PMC article.
The commensal Streptococcus salivarius K12 downregulates the innate immune responses of human epithelial cells and promotes host-microbe homeostasis.
Cosseau C, Devine DA, Dullaghan E, Gardy JL, Chikatamarla A, Gellatly S, Yu LL, Pistolic J, Falsafi R, Tagg J, Hancock RE. Cosseau C, et al. Infect Immun. 2008 Sep;76(9):4163-75. doi: 10.1128/IAI.00188-08. Epub 2008 Jul 14. Infect Immun. 2008. PMID: 18625732 Free PMC article.
The major outer membrane protein OprG of Pseudomonas aeruginosa contributes to cytotoxicity and forms an anaerobically regulated, cation-selective channel.
McPhee JB, Tamber S, Bains M, Maier E, Gellatly S, Lo A, Benz R, Hancock RE. McPhee JB, et al. FEMS Microbiol Lett. 2009 Jun;296(2):241-7. doi: 10.1111/j.1574-6968.2009.01651.x. Epub 2009 May 14. FEMS Microbiol Lett. 2009. PMID: 19486157
Host defence peptide LL-37 induces IL-6 expression in human bronchial epithelial cells by activation of the NF-kappaB signaling pathway.
Pistolic J, Cosseau C, Li Y, Yu JJ, Filewod NC, Gellatly S, Rehaume LM, Bowdish DM, Hancock RE. Pistolic J, et al. J Innate Immun. 2009;1(3):254-67. doi: 10.1159/000171533. Epub 2008 Nov 6. J Innate Immun. 2009. PMID: 20375583 Free PMC article.
Fibulin-1 regulates the pathogenesis of tissue remodeling in respiratory diseases.
Liu G, Cooley MA, Jarnicki AG, Hsu AC, Nair PM, Haw TJ, Fricker M, Gellatly SL, Kim RY, Inman MD, Tjin G, Wark PA, Walker MM, Horvat JC, Oliver BG, Argraves WS, Knight DA, Burgess JK, Hansbro PM. Liu G, et al. Among authors: gellatly sl. JCI Insight. 2016 Jun 16;1(9):e86380. doi: 10.1172/jci.insight.86380. JCI Insight. 2016. PMID: 27398409 Free PMC article.
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