Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1979 2
1981 1
1989 1
1990 2
1991 1
1994 1
1995 2
1996 1
1997 3
1999 1
2000 3
2001 1
2002 2
2003 10
2004 8
2005 11
2006 10
2007 17
2008 9
2009 9
2010 9
2011 23
2012 22
2013 22
2014 30
2015 28
2016 30
2017 28
2018 38
2019 27
2020 39
2021 64
2022 42
2023 27
2024 30
2025 45
2026 7

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

566 results

Results by year

Filters applied: Abstract. Clear all
Page 1
Malaria: past, present, and future.
Li Q, Liu T, Lv K, Liao F, Wang J, Tu Y, Chen Q. Li Q, et al. Signal Transduct Target Ther. 2025 Jun 17;10(1):188. doi: 10.1038/s41392-025-02246-3. Signal Transduct Target Ther. 2025. PMID: 40523953 Free PMC article. Review.
Despite advances in malaria treatment and prevention, the number of clinical cases and deaths have increased in recent years. ...Overall, this review provides a detailed summary of the latest progress in malaria research and emphasizes the need for continuous …
Despite advances in malaria treatment and prevention, the number of clinical cases and deaths have increased in recent years. …
Monoclonal antibodies for malaria prevention.
Aleshnick M, Florez-Cuadros M, Martinson T, Wilder BK. Aleshnick M, et al. Mol Ther. 2022 May 4;30(5):1810-1821. doi: 10.1016/j.ymthe.2022.04.001. Epub 2022 Apr 5. Mol Ther. 2022. PMID: 35395399 Free PMC article. Review.
While a monoclonal antibody approach to abrogating malaria infection is not yet available, the unique life cycle of the malaria parasite affords many opportunities for such proteins to act, and preliminary research into the efficacy of monoclonal antibodies in pr …
While a monoclonal antibody approach to abrogating malaria infection is not yet available, the unique life cycle of the malaria …
Gene-therapy for malaria prevention.
Rodrigues MM, Soares IS. Rodrigues MM, et al. Trends Parasitol. 2014 Nov;30(11):511-3. doi: 10.1016/j.pt.2014.09.005. Epub 2014 Oct 13. Trends Parasitol. 2014. PMID: 25444237
The limited number of tools for malaria prevention and the inability to eradicate the disease have required large investments in vaccine development, as vaccines have been the only foreseeable type of immunoprophylaxis against malaria. An alternative strategy …
The limited number of tools for malaria prevention and the inability to eradicate the disease have required large investments …
Relapse.
White NJ, Imwong M. White NJ, et al. Adv Parasitol. 2012;80:113-50. doi: 10.1016/B978-0-12-397900-1.00002-5. Adv Parasitol. 2012. PMID: 23199487 Review.
P. vivax infections are characterized by relapses of malaria arising from persistent liver stages of the parasite (hypnozoites), which can be prevented currently only by 8-aminoquinoline anti-malarials. ...These observations have important implications for the asses …
P. vivax infections are characterized by relapses of malaria arising from persistent liver stages of the parasite (hypnozoites), whic …
A molecular marker of artemisinin-resistant Plasmodium falciparum malaria.
Ariey F, Witkowski B, Amaratunga C, Beghain J, Langlois AC, Khim N, Kim S, Duru V, Bouchier C, Ma L, Lim P, Leang R, Duong S, Sreng S, Suon S, Chuor CM, Bout DM, Ménard S, Rogers WO, Genton B, Fandeur T, Miotto O, Ringwald P, Le Bras J, Berry A, Barale JC, Fairhurst RM, Benoit-Vical F, Mercereau-Puijalon O, Ménard D. Ariey F, et al. Nature. 2014 Jan 2;505(7481):50-5. doi: 10.1038/nature12876. Epub 2013 Dec 18. Nature. 2014. PMID: 24352242 Free PMC article.
Plasmodium falciparum resistance to artemisinin derivatives in southeast Asia threatens malaria control and elimination activities worldwide. To monitor the spread of artemisinin resistance, a molecular marker is urgently needed. ...K13-propeller polymorphism consti …
Plasmodium falciparum resistance to artemisinin derivatives in southeast Asia threatens malaria control and elimination activi …
Sampling for malaria molecular surveillance.
Mayor A, Ishengoma DS, Proctor JL, Verity R. Mayor A, et al. Trends Parasitol. 2023 Nov;39(11):954-968. doi: 10.1016/j.pt.2023.08.007. Epub 2023 Sep 19. Trends Parasitol. 2023. PMID: 37730525 Free PMC article. Review.
Strategic use of Plasmodium falciparum genetic variation has great potential to inform public health actions for malaria control and elimination. Malaria molecular surveillance (MMS) begins with a strategy to identify and collect parasite samples, guid …
Strategic use of Plasmodium falciparum genetic variation has great potential to inform public health actions for malaria co …
Protective antibodies target cryptic epitope unmasked by cleavage of malaria sporozoite protein.
Dacon C, Moskovitz R, Swearingen K, Da Silva Pereira L, Flores-Garcia Y, Aleshnick M, Kanatani S, Flynn B, Molina-Cruz A, Wollenberg K, Traver M, Kirtley P, Purser L, Dillon M, Bonilla B, Franco A, Petros S, Kritzberg J, Tucker C, Paez GG, Gupta P, Shears MJ, Pazzi J, Edgar JM, Teng AA, Belmonte A, Oda K, Doumbo S, Krymskaya L, Skinner J, Li S, Ghosal S, Kayentao K, Ongoiba A, Vaughan A, Campo JJ, Traore B, Barillas-Mury C, Wijayalath W, Idris A, Crompton PD, Sinnis P, Wilder BK, Zavala F, Seder RA, Wilson IA, Tan J. Dacon C, et al. Science. 2025 Jan 3;387(6729):eadr0510. doi: 10.1126/science.adr0510. Epub 2025 Jan 3. Science. 2025. PMID: 39745947 Free PMC article.
The most advanced monoclonal antibodies (mAbs) and vaccines against malaria target the central repeat region or closely related sequences within the Plasmodium falciparum circumsporozoite protein (PfCSP). ...This pGlu-CSP epitope is not targeted by current anti-PfCSP mAbs …
The most advanced monoclonal antibodies (mAbs) and vaccines against malaria target the central repeat region or closely related seque …
Sickle cell disease.
Meremikwu MM, Okomo U. Meremikwu MM, et al. BMJ Clin Evid. 2016 Jan 22;2016:2402. BMJ Clin Evid. 2016. PMID: 26808098 Free PMC article. Review.
In sub-Saharan Africa, up to one third of adults are carriers of the defective sickle cell gene, and 1% to 2% of babies are born with the disease. METHODS AND OUTCOMES: We conducted a systematic overview, aiming to answer the following clinical question: What are the effec …
In sub-Saharan Africa, up to one third of adults are carriers of the defective sickle cell gene, and 1% to 2% of babies are born with …
Natural malaria infection elicits rare but potent neutralizing antibodies to the blood-stage antigen RH5.
Wang LT, Cooper AJR, Farrell B, Miura K, Diouf A, Müller-Sienerth N, Crosnier C, Purser L, Kirtley PJ, Maciuszek M, Barrett JR, McHugh K, Ogwang R, Tucker C, Li S, Doumbo S, Doumtabe D, Pyo CW, Skinner J, Nielsen CM, Silk SE, Kayentao K, Ongoiba A, Zhao M, Nguyen DC, Lee FE, Minassian AM, Geraghty DE, Traore B, Seder RA, Wilder BK, Crompton PD, Wright GJ, Long CA, Draper SJ, Higgins MK, Tan J. Wang LT, et al. Cell. 2024 Sep 5;187(18):4981-4995.e14. doi: 10.1016/j.cell.2024.06.037. Epub 2024 Jul 25. Cell. 2024. PMID: 39059381 Free PMC article.
Here, we found that RH5-reactive B cells were rare, and circulating immunoglobulin G (IgG) responses to RH5 were short-lived in malaria-exposed Malian individuals, despite repeated infections over multiple years. RH5-specific monoclonal antibodies isolated from eight ma …
Here, we found that RH5-reactive B cells were rare, and circulating immunoglobulin G (IgG) responses to RH5 were short-lived in malaria …
Potent AMA1-specific human monoclonal antibody against Plasmodium vivax Pre-erythrocytic and Blood Stages.
Winnicki AC, Dietrich MH, Yeoh LM, Carias LL, Roobsoong W, Drago CL, Malachin AN, Redinger KR, Feufack-Donfack LB, Baldor L, Jung NC, McLaine OS, Skomorovska-Prokvolit Y, Orban A, Opi DH, Kirtley P, Nielson K, Aleshnick M, Zanghi G, Rezakhani N, Vaughan AM, Wilder BK, Sattabongkot J, Tham WH, Popovici J, Beeson JG, Bosch J, King CL. Winnicki AC, et al. Nat Commun. 2024 Dec 4;15(1):10556. doi: 10.1038/s41467-024-53848-4. Nat Commun. 2024. PMID: 39632799 Free PMC article.
New therapeutics are necessary for preventing Plasmodium vivax malaria due to easy transmissibility and dormancy in the liver that increases the clinical burden due to recurrent relapse. ...We have isolated a potent humAb that is isolate-transcendent, blocks both pr …
New therapeutics are necessary for preventing Plasmodium vivax malaria due to easy transmissibility and dormancy in the liver …
566 results