Archetypal Analysis of Kidney Allograft Biopsies Using Next-generation Sequencing Technology.
Cortes Garcia E, Giarraputo A, Racapé M, Goutaudier V, Ursule-Dufait C, de la Grange P, Letourneur F, Raynaud M, Couderau C, Mezine F, Dagobert J, Bestard O, Moreso F, Villard J, Halleck F, Giral M, Brouard S, Danger R, Gourraud PA, Rabant M, Couzi L, Le Quintrec M, Kamar N, Morelon E, Vrtovsnik F, Taupin JL, Snanoudj R, Legendre C, Anglicheau D, Budde K, Lefaucheur C, Loupy A, Aubert O.
Cortes Garcia E, et al.
Transplantation. 2025 May 1;109(5):871-880. doi: 10.1097/TP.0000000000005181. Epub 2024 Oct 23.
Transplantation. 2025.
PMID: 40261978
Differentially expressed genes were determined for 11 Banff lesions. An ElasticNet model was used for feature selection, and 4 machine learning classifiers were trained to predict the probability of presence of the lesions. ...The 8 NGS-based archetypes displayed distinct …
Differentially expressed genes were determined for 11 Banff lesions. An ElasticNet model was used for feature selection, and 4 machin …