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1993 4
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2,627 results

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The following term was not found in PubMed: Dev.15
Page 1
Somatic activation of the K-ras oncogene causes early onset lung cancer in mice.
Johnson L, Mercer K, Greenbaum D, Bronson RT, Crowley D, Tuveson DA, Jacks T. Johnson L, et al. Nature. 2001 Apr 26;410(6832):1111-6. doi: 10.1038/35074129. Nature. 2001. PMID: 11323676
About 30% of human tumours carry ras gene mutations. Of the three genes in this family (composed of K-ras, N-ras and H-ras), K-ras is the most frequently mutated member in human tumours, including adenocarcinomas of the pancreas ( approximately 70-90% incidence), colon ( a …
About 30% of human tumours carry ras gene mutations. Of the three genes in this family (composed of K-ras, N-ras and H-ras), K-ras is …
Caveolin-1, a putative tumour suppressor gene.
Razani B, Schlegel A, Liu J, Lisanti MP. Razani B, et al. Biochem Soc Trans. 2001 Aug;29(Pt 4):494-9. doi: 10.1042/bst0290494. Biochem Soc Trans. 2001. PMID: 11498016 Review.
Caveolae ('little caves') are plasma membrane specializations of 50-100 nm in diameter, and the caveolins are structural proteins used by cells to form caveolae. ...
Caveolae ('little caves') are plasma membrane specializations of 50-100 nm in diameter, and the caveolins are structural proteins use …
Skewed X inactivation in X-linked disorders.
Van den Veyver IB. Van den Veyver IB. Semin Reprod Med. 2001 Jun;19(2):183-91. doi: 10.1055/s-2001-15398. Semin Reprod Med. 2001. PMID: 11480916 Review.
X chromosome inactivation is a process by which the dosage of proteins transcribed from genes on the X chromosome is equalized between males (XY) and females (XX) through the silencing of most genes on one of the two X chromosomes in females. Although the choice of …
X chromosome inactivation is a process by which the dosage of proteins transcribed from genes on the X chromosome is equalized betwee …
Recent advances in hereditary spastic paraplegia.
Tallaksen CM, Dürr A, Brice A. Tallaksen CM, et al. Curr Opin Neurol. 2001 Aug;14(4):457-63. doi: 10.1097/00019052-200108000-00005. Curr Opin Neurol. 2001. PMID: 11470961 Review.
The genes that encode L1 and PLP were the first to be identified in HSP disorders. Surprisingly, the five genes encode proteins of different families, making understanding and diagnosis of HSP even more difficult. The discovery of new genes should hopefully h …
The genes that encode L1 and PLP were the first to be identified in HSP disorders. Surprisingly, the five genes encode protein …
Genomic organization of the mammalian MHC.
Kumánovics A, Takada T, Lindahl KF. Kumánovics A, et al. Annu Rev Immunol. 2003;21:629-57. doi: 10.1146/annurev.immunol.21.090501.080116. Epub 2001 Dec 19. Annu Rev Immunol. 2003. PMID: 12500978 Review.
The Human Genome Project transformed the quest of more than 50 years to understand the major histocompatibility complex (Mhc). The sequence of the Mhc from human and mouse, together with a large amount of sequence and mapping information from several other species, allows …
The Human Genome Project transformed the quest of more than 50 years to understand the major histocompatibility complex (Mhc). The se …
Roberts-SC phocomelia syndrome.
Maheshwari A, Kumar P, Dutta S, Narang A. Maheshwari A, et al. Indian J Pediatr. 2001 Jun;68(6):557-9. doi: 10.1007/BF02723253. Indian J Pediatr. 2001. PMID: 11450388 Review.
The phenotypic features match those described in the Roberts-SC phocomelia syndrome. A literature review revealed that 50% of these patients have chromosomal defects and antenatal detection is possible on ultrasound and by chromosome analysis of the amniocytes....
The phenotypic features match those described in the Roberts-SC phocomelia syndrome. A literature review revealed that 50% of these p …
Polymorphisms and colorectal tumor risk.
Houlston RS, Tomlinson IP. Houlston RS, et al. Gastroenterology. 2001 Aug;121(2):282-301. doi: 10.1053/gast.2001.26265. Gastroenterology. 2001. PMID: 11487538
METHODS: Fifty studies of the effect of common alleles of 13 genes on risk were identified. To clarify the impact of individual polymorphisms on risk, pooled analyses were performed. RESULTS: Of the 50 studies identified, significant associations were seen in 16, bu …
METHODS: Fifty studies of the effect of common alleles of 13 genes on risk were identified. To clarify the impact of individual polym …
The human genome structure and organization.
Makałowski W. Makałowski W. Acta Biochim Pol. 2001;48(3):587-98. Acta Biochim Pol. 2001. PMID: 11833767 Review.
Despite the fact that the nucleotide sequence of all chromosomes is established, the organisation of nuclear genome put still questions: for example: the exact number of genes encoded by the human genome is still unknown giving estimations from 30 to 150 thousand genes
Despite the fact that the nucleotide sequence of all chromosomes is established, the organisation of nuclear genome put still questions: for …
Missense mutations of human homeoboxes: A review.
D'Elia AV, Tell G, Paron I, Pellizzari L, Lonigro R, Damante G. D'Elia AV, et al. Hum Mutat. 2001 Nov;18(5):361-74. doi: 10.1002/humu.1207. Hum Mutat. 2001. PMID: 11668629 Review.
Seventy-four independent homeobox mutations have been observed in 17 different genes. In the same genes, 30 missense mutations outside the homeobox have been observed, indicating that the homeodomain is more easily affected by single amino acids changes than the res …
Seventy-four independent homeobox mutations have been observed in 17 different genes. In the same genes, 30 missense mutations …
Regulation of carbohydrate metabolism during Giardia encystment.
Jarroll EL, Macechko PT, Steimle PA, Bulik D, Karr CD, van Keulen H, Paget TA, Gerwig G, Kamerling J, Vliegenthart J, Erlandsen S. Jarroll EL, et al. J Eukaryot Microbiol. 2001 Jan-Feb;48(1):22-6. doi: 10.1111/j.1550-7408.2001.tb00412.x. J Eukaryot Microbiol. 2001. PMID: 11249189 Review.
Within 12 h, GPI and its activity are detectable and OU decreases 50% from non-encysting levels; glucose's stimulation and MTZ's inhibition of oxygen uptake cease. In contrast, aspartate uptake remained constant throughout the 40 h monitored. Two genes, gpi 1 and 2 …
Within 12 h, GPI and its activity are detectable and OU decreases 50% from non-encysting levels; glucose's stimulation and MTZ's inhi …
2,627 results