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Genetic association and machine learning improves discovery and prediction of type 1 diabetes.
McGrail C, Sears TJ, Kudtarkar P, Carter H, Gaulton K. McGrail C, et al. medRxiv [Preprint]. 2024 Aug 2:2024.07.31.24311310. doi: 10.1101/2024.07.31.24311310. medRxiv. 2024. PMID: 39132494 Free PMC article. Preprint.
Type 1 diabetes (T1D) has a large genetic component, and expanded genetic studies of T1D can lead to novel biological and therapeutic discovery and improved risk prediction. ...Finally, we provided T1GRS in formats to enhanc …
Type 1 diabetes (T1D) has a large genetic component, and expanded genetic studies of T1D can lead to nove …
DeepCOMBI: explainable artificial intelligence for the analysis and discovery in genome-wide association studies.
Mieth B, Rozier A, Rodriguez JA, Höhne MMC, Görnitz N, Müller KR. Mieth B, et al. NAR Genom Bioinform. 2021 Jul 20;3(3):lqab065. doi: 10.1093/nargab/lqab065. eCollection 2021 Sep. NAR Genom Bioinform. 2021. PMID: 34296082 Free PMC article.
Deep learning has revolutionized data science in many fields by greatly improving prediction performances in comparison to conventional approaches. ...DeepCOMBI is shown to outperform ordinary raw P-value thresholding and other baseline methods. Two novel dis …
Deep learning has revolutionized data science in many fields by greatly improving prediction performances in comparison …