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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 1
1996 1
2003 3
2004 1
2005 5
2006 2
2009 1
2010 2
2011 1
2012 2
2013 2
2014 1
2015 3
2017 2
2018 5
2019 3
2020 1
2021 3
2022 1
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38 results
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Page 1
A quantitative analysis of cohesin decay in mitotic fidelity.
Carvalhal S, Tavares A, Santos MB, Mirkovic M, Oliveira RA. Carvalhal S, et al. J Cell Biol. 2018 Oct 1;217(10):3343-3353. doi: 10.1083/jcb.201801111. Epub 2018 Jul 12. J Cell Biol. 2018. PMID: 30002073 Free PMC article.
However, it is unclear what effects a partial decline of cohesin may have on chromosome organization. In this study, we provide a quantitative analysis of cohesin decay by inducing acute removal of defined amounts of cohesin from metaphase-arrested chromosomes
However, it is unclear what effects a partial decline of cohesin may have on chromosome organization. In this study, we provide a qua …
The evolution of sex chromosomes in organisms with separate haploid sexes.
Immler S, Otto SP. Immler S, et al. Evolution. 2015 Mar;69(3):694-708. doi: 10.1111/evo.12602. Epub 2015 Feb 20. Evolution. 2015. PMID: 25582562
In a second step, we test how prone nonrecombining regions are to degeneration due to accumulation of deleterious mutations. Our modeling predicts that the decay of recombination on the sex chromosomes and the addition of strata via fusions will be just as much a pa …
In a second step, we test how prone nonrecombining regions are to degeneration due to accumulation of deleterious mutations. Our modeling pr …
Genetic analysis of isoform usage in the human anti-viral response reveals influenza-specific regulation of ERAP2 transcripts under balancing selection.
Ye CJ, Chen J, Villani AC, Gate RE, Subramaniam M, Bhangale T, Lee MN, Raj T, Raychowdhury R, Li W, Rogel N, Simmons S, Imboywa SH, Chipendo PI, McCabe C, Lee MH, Frohlich IY, Stranger BE, De Jager PL, Regev A, Behrens T, Hacohen N. Ye CJ, et al. Genome Res. 2018 Dec;28(12):1812-1825. doi: 10.1101/gr.240390.118. Epub 2018 Nov 16. Genome Res. 2018. PMID: 30446528 Free PMC article.
Both eQTLs and isoQTLs explain a significant proportion of the disease heritability attributed to common genetic variants. At the ERAP2 locus, we shed light on the function of the gene and how two frequent, highly differentiated haplotypes with intermediate frequencies cou …
Both eQTLs and isoQTLs explain a significant proportion of the disease heritability attributed to common genetic variants. At the ERA …
The cerebellar degeneration in ataxia-telangiectasia: A case for genome instability.
Shiloh Y. Shiloh Y. DNA Repair (Amst). 2020 Nov;95:102950. doi: 10.1016/j.dnarep.2020.102950. Epub 2020 Aug 23. DNA Repair (Amst). 2020. PMID: 32871349 Review.
Ataxi A-T elangiectasia (A-T) is a prominent example of this process. A-T's hallmarks are progressive cerebellar degeneration, immunodeficiency, chronic lung disease, cancer predisposition, endocrine abnormalities, segmental premature aging, chromosomal instability …
Ataxi A-T elangiectasia (A-T) is a prominent example of this process. A-T's hallmarks are progressive cerebellar degeneration, immuno …
Defects in spliceosomal machinery: a new pathway of leukaemogenesis.
Maciejewski JP, Padgett RA. Maciejewski JP, et al. Br J Haematol. 2012 Jul;158(2):165-173. doi: 10.1111/j.1365-2141.2012.09158.x. Epub 2012 May 18. Br J Haematol. 2012. PMID: 22594801 Free PMC article. Review.
Theoretically, spliceosomal mutations can lead to activation of incorrect splice sites, intron retention or aberrant alternative splicing occurring in patterns generated by mutations of individual spliceosomal proteins. Such events can produce a defective balance between p …
Theoretically, spliceosomal mutations can lead to activation of incorrect splice sites, intron retention or aberrant alternative splicing oc …
Genetic properties of the MAGIC maize population: a new platform for high definition QTL mapping in Zea mays.
Dell'Acqua M, Gatti DM, Pea G, Cattonaro F, Coppens F, Magris G, Hlaing AL, Aung HH, Nelissen H, Baute J, Frascaroli E, Churchill GA, Inzé D, Morgante M, Pè ME. Dell'Acqua M, et al. Genome Biol. 2015 Sep 11;16(1):167. doi: 10.1186/s13059-015-0716-z. Genome Biol. 2015. PMID: 26357913 Free PMC article.
RESULTS: We produced 1,636 MAGIC maize recombinant inbred lines derived from eight genetically diverse founder lines. The characterization of 529 MAGIC maize lines shows that the population is a balanced, evenly differentiated mosaic of the eight founders, with mapp …
RESULTS: We produced 1,636 MAGIC maize recombinant inbred lines derived from eight genetically diverse founder lines. The characteriz …
Evolutionary explanations of the "actuarial senescence in the wild" and of the "state of senility".
Libertini G. Libertini G. ScientificWorldJournal. 2006 Aug 31;6:1086-108. doi: 10.1100/tsw.2006.209. ScientificWorldJournal. 2006. PMID: 16951902 Free PMC article. Review.
A large set of data suggests that progressive reduction of fitness and senile decay in vertebrates are in correlation with the decline of cell replication capacities. ...For IMICAW, it should be substituted with the concept of a physiologic phenomenon genetically de …
A large set of data suggests that progressive reduction of fitness and senile decay in vertebrates are in correlation with the declin …
Single nucleotide polymorphisms reveal genetic diversity in New Mexican chile peppers (Capsicum spp.).
Lozada DN, Bhatta M, Coon D, Bosland PW. Lozada DN, et al. BMC Genomics. 2021 May 17;22(1):356. doi: 10.1186/s12864-021-07662-7. BMC Genomics. 2021. PMID: 34000992 Free PMC article.
Tajima's D values demonstrated positive selection, population bottleneck, and balancing selection for the New Mexico Capsicum population. ...CONCLUSIONS: Genetic diversity among New Mexican chile peppers was evaluated using GBS-derived SNP markers and gene
Tajima's D values demonstrated positive selection, population bottleneck, and balancing selection for the New Mexico Capsicum …
Transcript-level expression control of plant NLR genes.
Lai Y, Eulgem T. Lai Y, et al. Mol Plant Pathol. 2018 May;19(5):1267-1281. doi: 10.1111/mpp.12607. Epub 2017 Nov 20. Mol Plant Pathol. 2018. PMID: 28834153 Free PMC article. Review.
Multiple mechanistic steps, including transcription as well as co-/post-transcriptional processing and transcript turn-over, contribute to balanced base levels of NLR transcripts and allow for dynamic adjustments to defence situations....
Multiple mechanistic steps, including transcription as well as co-/post-transcriptional processing and transcript turn-over, contribute to …
Bioinformatics analysis of alternative splicing.
Lee C, Wang Q. Lee C, et al. Brief Bioinform. 2005 Mar;6(1):23-33. doi: 10.1093/bib/6.1.23. Brief Bioinform. 2005. PMID: 15826354 Review.
A number of groups have used a combination of bioinformatics, comparative genomics and experimental validation to identify new motifs for splice regulatory factors, analyse the balance of factors that regulate alternative splicing, and propose a new mechanism for regulatio …
A number of groups have used a combination of bioinformatics, comparative genomics and experimental validation to identify new motifs for sp …
38 results