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Genetic variability in the renin-angiotensin system: prevalence of alleles and genotypes.
Staessen JA, Ginocchio G, Wang JG, Saavedra AP, Soubrier F, Vlietinck R, Fagard R. Staessen JA, et al. J Cardiovasc Risk. 1997 Oct-Dec;4(5-6):401-22. J Cardiovasc Risk. 1997. PMID: 9865673 Review.
METHODS: This systematic review of the literature investigated genetic variation in the renin system according to race, sex and age. ...CONCLUSION: With adjustments applied for the subjects' enrollment group and the methods of genotyping, genetic
METHODS: This systematic review of the literature investigated genetic variation in the renin system according to race, …
Genetic polymorphism of the renin-angiotensin system and organ damage in essential hypertension.
Pontremoli R, Ravera M, Viazzi F, Nicolella C, Berruti V, Leoncini G, Giacopelli F, Bezante GP, Sacchi G, Ravazzolo R, Deferrari G. Pontremoli R, et al. Kidney Int. 2000 Feb;57(2):561-9. doi: 10.1046/j.1523-1755.2000.00876.x. Kidney Int. 2000. PMID: 10652033 Free article.
BACKGROUND: The renin-angiotensin-aldosterone system (RAAS) plays a significant role in the development of hypertensive cardiac and vascular remodeling. ...No differences in the prevalence and degree of target organ damage (TOD) were found when data we …
BACKGROUND: The renin-angiotensin-aldosterone system (RAAS) plays a significant role in the development of hypertensive …
Genetic polymorphisms of the renin-angiotensin system and the outcome of focal segmental glomerulosclerosis in children.
Frishberg Y, Becker-Cohen R, Halle D, Feigin E, Eisenstein B, Halevy R, Lotan D, Juabeh I, Ish-Shalom N, Magen D, Shvil Y, Sinai-Treiman L, Drukker A. Frishberg Y, et al. Kidney Int. 1998 Dec;54(6):1843-9. doi: 10.1046/j.1523-1755.1998.00218.x. Kidney Int. 1998. PMID: 9853248 Free article.
The purpose of our study was to compare the frequency of three polymorphisms of the renin-angiotensin system (RAS) in children with FSGS with that in healthy controls of matching ethnic groups, and to determine whether the clinical outcome of FSGS was associa …
The purpose of our study was to compare the frequency of three polymorphisms of the renin-angiotensin system (RAS) in c …
Are "functionally related polymorphisms" of renin-angiotensin-aldosterone system gene polymorphisms associated with hypertension?
Hahntow IN, Mairuhu G, van Valkengoed IG, Koopmans RP, Michel MC. Hahntow IN, et al. BMC Cardiovasc Disord. 2010 Jun 2;10:23. doi: 10.1186/1471-2261-10-23. BMC Cardiovasc Disord. 2010. PMID: 20525211 Free PMC article.
We have tested this hypothesis using genes encoding components of the renin-angiotensin-aldosterone system and the high blood pressure phenotype. ...CONCLUSIONS: We conclude that combinations of physiologically related polymorphisms of multiple genes, at leas …
We have tested this hypothesis using genes encoding components of the renin-angiotensin-aldosterone system and the high …
Ten renin-angiotensin system-related gene polymorphisms in maximally treated Canadian Caucasian patients with heart failure.
Zakrzewski-Jakubiak M, de Denus S, Dubé MP, Bélanger F, White M, Turgeon J. Zakrzewski-Jakubiak M, et al. Br J Clin Pharmacol. 2008 May;65(5):742-51. doi: 10.1111/j.1365-2125.2007.03091.x. Epub 2008 Feb 12. Br J Clin Pharmacol. 2008. PMID: 18279468 Free PMC article. Clinical Trial.
We tested for a difference in prevalence of 10 renin-angiotensin-aldosterone system (RAAS)-related gene polymorphisms between a homogenous population of HF patients and healthy controls. ...RESULTS The AGT (T235) allele (P = 0.0025, OR 2.02, 95% …
We tested for a difference in prevalence of 10 renin-angiotensin-aldosterone system (RAAS)-related gene polymorp …
Allele С (rs5186) of at1r is associated with the severity of COVID-19 in the Ukrainian population.
Izmailova O, Shlykova O, Vatsenko A, Ivashchenko D, Dudchenko M, Koval T, Kaidashev I. Izmailova O, et al. Infect Genet Evol. 2022 Mar;98:105227. doi: 10.1016/j.meegid.2022.105227. Epub 2022 Jan 25. Infect Genet Evol. 2022. PMID: 35091110 Free PMC article.
INTRODUCTION: The severity of SARS-CoV-2 induced coronavirus disease 19 (COVID-19) depends on the presence of risk factors and the hosts' gene variability. There are preliminary results that gene polymorphisms of the renin-angiotensin system can influe …
INTRODUCTION: The severity of SARS-CoV-2 induced coronavirus disease 19 (COVID-19) depends on the presence of risk factors and the hosts' ge …
The combination of ACE I/D and ACE2 G8790A polymorphisms revels susceptibility to hypertension: A genetic association study in Brazilian patients.
Pinheiro DS, Santos RS, Jardim PCBV, Silva EG, Reis AAS, Pedrino GR, Ulhoa CJ. Pinheiro DS, et al. PLoS One. 2019 Aug 20;14(8):e0221248. doi: 10.1371/journal.pone.0221248. eCollection 2019. PLoS One. 2019. PMID: 31430320 Free PMC article.
Angiotensin I-converting enzymes, ACE and ACE2, are key regulators of blood pressure that have counterbalance roles by acting on vasoactive peptides from Renin-Angiotensin-Aldosterone System (RAAS). ...No-association was verified for each gene individu
Angiotensin I-converting enzymes, ACE and ACE2, are key regulators of blood pressure that have counterbalance roles by acting on vaso
Variation in the region of the angiotensin-converting enzyme gene influences interindividual differences in blood pressure levels in young white males.
Fornage M, Amos CI, Kardia S, Sing CF, Turner ST, Boerwinkle E. Fornage M, et al. Circulation. 1998 May 12;97(18):1773-9. doi: 10.1161/01.cir.97.18.1773. Circulation. 1998. PMID: 9603530
BACKGROUND: The renin-angiotensin system regulates blood pressure through its effects on vascular tone, renal hemodynamics, and renal sodium and fluid balance. ...We rejected the null hypothesis that allelic variation in the region of the angiotensi
BACKGROUND: The renin-angiotensin system regulates blood pressure through its effects on vascular tone, renal hemodynam …
ACE Gene Variants Rise the Risk of Severe COVID-19 in Patients With Hypertension, Dyslipidemia or Diabetes: A Spanish Pilot Study.
Íñiguez M, Pérez-Matute P, Villoslada-Blanco P, Recio-Fernandez E, Ezquerro-Pérez D, Alba J, Ferreira-Laso ML, Oteo JA. Íñiguez M, et al. Front Endocrinol (Lausanne). 2021 Aug 19;12:688071. doi: 10.3389/fendo.2021.688071. eCollection 2021. Front Endocrinol (Lausanne). 2021. PMID: 34489863 Free PMC article.
It is essential to identify those risk factors that lead to a poor prognosis of the disease. A predisposing host genetic background could be one of these factors that explain the interindividual variability to COVID-19 severity. Thus, we have studied whether the rs4 …
It is essential to identify those risk factors that lead to a poor prognosis of the disease. A predisposing host genetic background c …
Angiotensin-converting enzyme insertion/deletion polymorphism, 24-h blood pressure profile and left ventricular hypertrophy in hypertensive individuals: a cross-sectional study.
Cosenso-Martin LN, Vaz-de-Melo RO, Pereira LR, Cesarino CB, Yugar-Toledo JC, Cipullo JP, de Souza Pinhel MA, Souza DR, Vilela-Martin JF. Cosenso-Martin LN, et al. Eur J Med Res. 2015 Sep 4;20(1):74. doi: 10.1186/s40001-015-0166-9. Eur J Med Res. 2015. PMID: 26336879 Free PMC article.
BACKGROUND: The absence of nocturnal blood pressure dipping (ND) identified by 24-h ambulatory blood pressure monitoring (ABPM) correlates with a worse cardiovascular prognosis. The renin-angiotensin system influences blood pressure levels and the occurrence …
BACKGROUND: The absence of nocturnal blood pressure dipping (ND) identified by 24-h ambulatory blood pressure monitoring (ABPM) correlates w …
13 results