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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2004 1
2007 1
2009 2
2010 1
2011 2
2012 2
2013 5
2014 2
2015 4
2016 3
2017 2
2018 3
2019 2
2020 2
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Genetically predicted body mass index and Alzheimer's disease-related phenotypes in three large samples: Mendelian randomization analyses.
Mukherjee S, Walter S, Kauwe JSK, Saykin AJ, Bennett DA, Larson EB, Crane PK, Glymour MM; Adult Changes in Thought Study Investigators; Religious Orders Study/Memory and Aging Project Investigators; Alzheimer's Disease Genetics Consortium. Mukherjee S, et al. Alzheimers Dement. 2015 Dec;11(12):1439-1451. doi: 10.1016/j.jalz.2015.05.015. Epub 2015 Jun 12. Alzheimers Dement. 2015. PMID: 26079416 Free PMC article.
Observational research shows that higher body mass index (BMI) increases Alzheimer's disease (AD) risk, but it is unclear whether this association is causal. ...We evaluated individual-level data from the AD Genetics Consortium (AD …
Observational research shows that higher body mass index (BMI) increases Alzheimer's disease (AD) …
Risk factors for predicting progression from mild cognitive impairment to Alzheimer's disease: a systematic review and meta-analysis of cohort studies.
Li JQ, Tan L, Wang HF, Tan MS, Tan L, Xu W, Zhao QF, Wang J, Jiang T, Yu JT. Li JQ, et al. J Neurol Neurosurg Psychiatry. 2016 May;87(5):476-84. doi: 10.1136/jnnp-2014-310095. Epub 2015 May 22. J Neurol Neurosurg Psychiatry. 2016. PMID: 26001840 Review.
OBJECTIVE: We sought to identify the risk factors for predicting the progression from mild cognitive impairment (MCI) to Alzheimer's disease (AD). ...Negative associations were found for high body mass index (RR=0.85, 95% CI=0.76 t …
OBJECTIVE: We sought to identify the risk factors for predicting the progression from mild cognitive impairment (MCI) to Alzheimer
Associations between Potentially Modifiable Risk Factors and Alzheimer Disease: A Mendelian Randomization Study.
Østergaard SD, Mukherjee S, Sharp SJ, Proitsi P, Lotta LA, Day F, Perry JR, Boehme KL, Walter S, Kauwe JS, Gibbons LE; Alzheimer’s Disease Genetics Consortium; GERAD1 Consortium; EPIC-InterAct Consortium, Larson EB, Powell JF, Langenberg C, Crane PK, Wareham NJ, Scott RA. Østergaard SD, et al. PLoS Med. 2015 Jun 16;12(6):e1001841; discussion e1001841. doi: 10.1371/journal.pmed.1001841. eCollection 2015 Jun. PLoS Med. 2015. PMID: 26079503 Free PMC article.
BACKGROUND: Potentially modifiable risk factors including obesity, diabetes, hypertension, and smoking are associated with Alzheimer disease (AD) and represent promising targets for intervention. ...We considered type 2 diabetes (T2D, NSNPs = 49), fasting glucose (N …
BACKGROUND: Potentially modifiable risk factors including obesity, diabetes, hypertension, and smoking are associated with Alzheimer
Systemic inflammation as a predictor of brain aging: Contributions of physical activity, metabolic risk, and genetic risk.
Corlier F, Hafzalla G, Faskowitz J, Kuller LH, Becker JT, Lopez OL, Thompson PM, Braskie MN. Corlier F, et al. Neuroimage. 2018 May 15;172:118-129. doi: 10.1016/j.neuroimage.2017.12.027. Epub 2018 Jan 28. Neuroimage. 2018. PMID: 29357308 Free PMC article. Clinical Trial.
Inflammatory processes may contribute to risk for Alzheimer's disease (AD) and age-related brain degeneration. Metabolic and genetic risk factors, and physical activity may, in turn, influence these inflammatory processes. ...Higher baseline CRP levels …
Inflammatory processes may contribute to risk for Alzheimer's disease (AD) and age-related brain degeneration. Metaboli …
Models for predicting risk of dementia: a systematic review.
Hou XH, Feng L, Zhang C, Cao XP, Tan L, Yu JT. Hou XH, et al. J Neurol Neurosurg Psychiatry. 2019 Apr;90(4):373-379. doi: 10.1136/jnnp-2018-318212. Epub 2018 Jun 28. J Neurol Neurosurg Psychiatry. 2019. PMID: 29954871
RESULTS: Of 8462 studies reviewed, 61 articles describing dementia risk models were identified, with the majority of the articles modelling late life risk (n=39), followed by those modelling prediction of mild cognitive impairment to Alzheimer's disease
RESULTS: Of 8462 studies reviewed, 61 articles describing dementia risk models were identified, with the majority of the articles modelling …
Increased blood-brain barrier permeability is associated with dementia and diabetes but not amyloid pathology or APOE genotype.
Janelidze S, Hertze J, Nägga K, Nilsson K, Nilsson C; Swedish BioFINDER Study Group, Wennström M, van Westen D, Blennow K, Zetterberg H, Hansson O. Janelidze S, et al. Neurobiol Aging. 2017 Mar;51:104-112. doi: 10.1016/j.neurobiolaging.2016.11.017. Epub 2016 Dec 5. Neurobiol Aging. 2017. PMID: 28061383 Free PMC article.
The ratio was increased in patients with Alzheimer's disease, dementia with Lewy bodies or Parkinson's disease dementia, subcortical vascular dementia, and frontotemporal dementia compared with controls. ...In healthy elderly, high body
The ratio was increased in patients with Alzheimer's disease, dementia with Lewy bodies or Parkinson's diseas
Shared genetic aetiology between cognitive functions and physical and mental health in UK Biobank (N=112 151) and 24 GWAS consortia.
Hagenaars SP, Harris SE, Davies G, Hill WD, Liewald DC, Ritchie SJ, Marioni RE, Fawns-Ritchie C, Cullen B, Malik R; METASTROKE Consortium, International Consortium for Blood Pressure GWAS; SpiroMeta Consortium; CHARGE Consortium Pulmonary Group, CHARGE Consortium Aging and Longevity Group, Worrall BB, Sudlow CL, Wardlaw JM, Gallacher J, Pell J, McIntosh AM, Smith DJ, Gale CR, Deary IJ. Hagenaars SP, et al. Mol Psychiatry. 2016 Nov;21(11):1624-1632. doi: 10.1038/mp.2015.225. Epub 2016 Jan 26. Mol Psychiatry. 2016. PMID: 26809841 Free PMC article.
In addition, highly significant associations were observed between the cognitive test scores in the UK Biobank sample and many polygenic profile scores, including coronary artery disease, stroke, Alzheimer's disease, schizophrenia, autism, major depres …
In addition, highly significant associations were observed between the cognitive test scores in the UK Biobank sample and many polygenic pro …
Decreased levels of circulating adiponectin in mild cognitive impairment and Alzheimer's disease.
Teixeira AL, Diniz BS, Campos AC, Miranda AS, Rocha NP, Talib LL, Gattaz WF, Forlenza OV. Teixeira AL, et al. Neuromolecular Med. 2013 Mar;15(1):115-21. doi: 10.1007/s12017-012-8201-2. Epub 2012 Sep 28. Neuromolecular Med. 2013. PMID: 23055000
We further evaluated whether circulating adiponectin levels could predict progression from MCI to Alzheimer's disease upon follow-up. ...Circulating adiponectin levels did not predict cognitive decline in the elderly controls (i.e., progression …
We further evaluated whether circulating adiponectin levels could predict progression from MCI to Alzheimer's diseas
A novel healthy metabolic phenotype developed among a cohort of families enriched for longevity.
Marron MM, Miljkovic I, Boudreau RM, Christensen K, Feitosa MF, Lee JH, Sebastiani P, Thyagarajan B, Wojczynski MK, Zmuda JM, Newman AB; Long Life Family Study. Marron MM, et al. Metabolism. 2019 May;94:28-38. doi: 10.1016/j.metabol.2019.01.010. Epub 2019 Jan 30. Metabolism. 2019. PMID: 30710575 Free PMC article. Clinical Trial.
Dysregulation in metabolic pathways has also shown to predict accelerated aging. Using information from the Long Life Family Study (LLFS), a multi-center study of two-generation families selected for exceptional longevity, we developed an indicator of healthy metabolism to …
Dysregulation in metabolic pathways has also shown to predict accelerated aging. Using information from the Long Life Family Study (L …
The Price of Stress: High Bedtime Salivary Cortisol Levels Are Associated with Brain Atrophy and Cognitive Decline in Stroke Survivors. Results from the TABASCO Prospective Cohort Study.
Tene O, Hallevi H, Korczyn AD, Shopin L, Molad J, Kirschbaum C, Bornstein NM, Shenhar-Tsarfaty S, Kliper E, Auriel E, Usher S, Stalder T, Ben Assayag E. Tene O, et al. J Alzheimers Dis. 2018;65(4):1365-1375. doi: 10.3233/JAD-180486. J Alzheimers Dis. 2018. PMID: 30149451
However, limited data exist regarding associations between post-stroke cortisol levels, brain abnormalities, genetic factors, and cognitive outcome. ...These findings remained significant when adjusted for age, gender, education, smoking, stroke severity, apolipoprotein E4 …
However, limited data exist regarding associations between post-stroke cortisol levels, brain abnormalities, genetic factors, and cog …
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