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Label-free identification of activated T lymphocytes through tridimensional microsensors on chip.
Rollo E, Tenaglia E, Genolet R, Bianchi E, Harari A, Coukos G, Guiducci C. Rollo E, et al. Among authors: Genolet R. Biosens Bioelectron. 2017 Aug 15;94:193-199. doi: 10.1016/j.bios.2017.02.047. Epub 2017 Mar 3. Biosens Bioelectron. 2017. PMID: 28284079
Sensitive and frequent identification of high avidity neo-epitope specific CD8 + T cells in immunotherapy-naive ovarian cancer.
Bobisse S, Genolet R, Roberti A, Tanyi JL, Racle J, Stevenson BJ, Iseli C, Michel A, Le Bitoux MA, Guillaume P, Schmidt J, Bianchi V, Dangaj D, Fenwick C, Derré L, Xenarios I, Michielin O, Romero P, Monos DS, Zoete V, Gfeller D, Kandalaft LE, Coukos G, Harari A. Bobisse S, et al. Among authors: Genolet R. Nat Commun. 2018 Mar 15;9(1):1092. doi: 10.1038/s41467-018-03301-0. Nat Commun. 2018. PMID: 29545564 Free PMC article.
Personalized cancer vaccine effectively mobilizes antitumor T cell immunity in ovarian cancer.
Tanyi JL, Bobisse S, Ophir E, Tuyaerts S, Roberti A, Genolet R, Baumgartner P, Stevenson BJ, Iseli C, Dangaj D, Czerniecki B, Semilietof A, Racle J, Michel A, Xenarios I, Chiang C, Monos DS, Torigian DA, Nisenbaum HL, Michielin O, June CH, Levine BL, Powell DJ Jr, Gfeller D, Mick R, Dafni U, Zoete V, Harari A, Coukos G, Kandalaft LE. Tanyi JL, et al. Among authors: Genolet R. Sci Transl Med. 2018 Apr 11;10(436):eaao5931. doi: 10.1126/scitranslmed.aao5931. Sci Transl Med. 2018. PMID: 29643231
High-throughput Screening of Human Tumor Antigen-specific CD4 T Cells, Including Neoantigen-reactive T Cells.
Costa-Nunes C, Cachot A, Bobisse S, Arnaud M, Genolet R, Baumgaertner P, Speiser DE, Sousa Alves PM, Sandoval F, Adotévi O, Reith W, Protti MP, Coukos G, Harari A, Romero P, Jandus C. Costa-Nunes C, et al. Among authors: Genolet R. Clin Cancer Res. 2019 Jul 15;25(14):4320-4331. doi: 10.1158/1078-0432.CCR-18-1356. Epub 2019 Apr 23. Clin Cancer Res. 2019. PMID: 31015344
Duality of the murine CD8 compartment.
Genolet R, Leignadier J, Østerås M, Farinelli L, Stevenson BJ, Luescher IF. Genolet R, et al. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):E1007-15. doi: 10.1073/pnas.1317847111. Epub 2014 Mar 4. Proc Natl Acad Sci U S A. 2014. PMID: 24594598 Free PMC article.
CTLA-4 controls the thymic development of both conventional and regulatory T cells through modulation of the TCR repertoire.
Verhagen J, Genolet R, Britton GJ, Stevenson BJ, Sabatos-Peyton CA, Dyson J, Luescher IF, Wraith DC. Verhagen J, et al. Among authors: Genolet R. Proc Natl Acad Sci U S A. 2013 Jan 15;110(3):E221-30. doi: 10.1073/pnas.1208573110. Epub 2012 Dec 24. Proc Natl Acad Sci U S A. 2013. PMID: 23267099 Free PMC article.
KAP1 regulates gene networks controlling T-cell development and responsiveness.
Santoni de Sio FR, Barde I, Offner S, Kapopoulou A, Corsinotti A, Bojkowska K, Genolet R, Thomas JH, Luescher IF, Pinschewer D, Harris N, Trono D. Santoni de Sio FR, et al. Among authors: Genolet R. FASEB J. 2012 Nov;26(11):4561-75. doi: 10.1096/fj.12-206177. Epub 2012 Aug 7. FASEB J. 2012. PMID: 22872677 Free PMC article.
The T-cell receptor is not hardwired to engage MHC ligands.
Holland SJ, Bartok I, Attaf M, Genolet R, Luescher IF, Kotsiou E, Richard A, Wang E, White M, Coe DJ, Chai JG, Ferreira C, Dyson J. Holland SJ, et al. Among authors: Genolet R. Proc Natl Acad Sci U S A. 2012 Nov 6;109(45):E3111-8. doi: 10.1073/pnas.1210882109. Epub 2012 Oct 17. Proc Natl Acad Sci U S A. 2012. PMID: 23077253 Free PMC article.
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