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2010 1
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Genome-wide association study identifies variants in the CFH region associated with host susceptibility to meningococcal disease.
Davila S, Wright VJ, Khor CC, Sim KS, Binder A, Breunis WB, Inwald D, Nadel S, Betts H, Carrol ED, de Groot R, Hermans PW, Hazelzet J, Emonts M, Lim CC, Kuijpers TW, Martinon-Torres F, Salas A, Zenz W, Levin M, Hibberd ML; International Meningococcal Genetics Consortium. Davila S, et al. Nat Genet. 2010 Sep;42(9):772-6. doi: 10.1038/ng.640. Epub 2010 Aug 8. Nat Genet. 2010. PMID: 20694013
Genetic factors contribute to host susceptibility and progression to disease, but the genes responsible for disease development are largely unknown. We report here a genome-wide association study for host susceptib
Genetic factors contribute to host susceptibility and progression to disease, but the genes responsible for disease
Genome-wide association studies reveal the role of polymorphisms affecting factor H binding protein expression in host invasion by Neisseria meningitidis.
Earle SG, Lobanovska M, Lavender H, Tang C, Exley RM, Ramos-Sevillano E, Browning DF, Kostiou V, Harrison OB, Bratcher HB, Varani G, Tang CM, Wilson DJ, Maiden MCJ. Earle SG, et al. PLoS Pathog. 2021 Oct 18;17(10):e1009992. doi: 10.1371/journal.ppat.1009992. eCollection 2021 Oct. PLoS Pathog. 2021. PMID: 34662348 Free PMC article.
An initial GWAS discovered bacterial genetic variants, including single nucleotide polymorphisms (SNPs), associated with invasive meningococcal disease (IMD) versus carriage in several loci across the meningococcal genome, encoding antige …
An initial GWAS discovered bacterial genetic variants, including single nucleotide polymorphisms (SNPs), associated with invas …