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Genome-wide 5-hydroxymethylcytosine patterns in human spermatogenesis are associated with semen quality.
Efimova OA, Pendina AA, Tikhonov AV, Parfenyev SE, Mekina ID, Komarova EM, Mazilina MA, Daev EV, Chiryaeva OG, Galembo IA, Krapivin MI, Glotov OS, Stepanova IS, Shlykova SA, Kogan IY, Gzgzyan AM, Kuznetzova TV, Baranov VS. Efimova OA, et al. Oncotarget. 2017 Jun 1;8(51):88294-88307. doi: 10.18632/oncotarget.18331. eCollection 2017 Oct 24. Oncotarget. 2017. PMID: 29179435 Free PMC article.
The percentage of highly hydroxymethylated spermatozoa correlated strongly negatively with the indicators of good semen quality - normal morphology (r=-0.567, P<0.0001) and normal head morphology (r=-0.609, P<0.0001) - and strongly positively with the indicato …
The percentage of highly hydroxymethylated spermatozoa correlated strongly negatively with the indicators of good semen quality
Genome-wide 5-hydroxymethylcytosine modification pattern is a novel epigenetic feature of globozoospermia.
Wang XX, Sun BF, Jiao J, Chong ZC, Chen YS, Wang XL, Zhao Y, Zhou YM, Li D. Wang XX, et al. Oncotarget. 2015 Mar 30;6(9):6535-43. doi: 10.18632/oncotarget.3163. Oncotarget. 2015. PMID: 25762640 Free PMC article.
Discovery of 5-hydroxymethylcytosine (5hmC) in mammalian genomes has excited the field of epigenetics, but information on the genome-wide distribution of 5hmC is limited. ...These results suggested that differences in genome-wide 5hmC …
Discovery of 5-hydroxymethylcytosine (5hmC) in mammalian genomes has excited the field of epigenetics, but information on the …