Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.
PLoS Genet. 2014.
PMID: 25188341
Free PMC article.
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Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias.
Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel JP, Younkin SG, Bennett DA, De Jager PL, Larson EB, Crane PK, Kamboh MI, Kofler JK, Mash DC, Duque L, Gilbert JR, Gwirtsman H, Buxbaum JD, Kramer P, Dickson DW, Farrer LA, Frosch MP, Ghetti B, Haines JL, Hyman BT, Kukull WA, Mayeux RP, Pericak-Vance MA, Schneider JA, Trojanowski JQ, Reiman EM; Alzheimer's Disease Genetics Consortium (ADGC); Schellenberg GD, Montine TJ.
Beecham GW, et al.
PLoS Genet. 2014 Sep 4;10(9):e1004606. doi: 10.1371/journal.pgen.1004606. eCollection 2014 Sep.
PLoS Genet. 2014.
PMID: 25188341
Free PMC article.
Alzheimer's disease (AD) and related dementias are a major public health challenge and present a therapeutic imperative for which we need additional insight into molecular pathogenesis. We performed a genome-wide association study and ana …
Alzheimer's disease (AD) and related dementias are a major public health challenge and present a therapeutic imperative …
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Hypothesis-based investigation of known AD risk variants reveals the genetic underpinnings of neuropathological lesions observed in Alzheimer's-type dementia.
Laureyssen C, Küçükali F, Van Dongen J, Gawor K, Tomé SO, Ronisz A, Otto M, von Arnim CAF, Van Damme P, Vandenberghe R, Thal DR, Sleegers K.
Laureyssen C, et al.
Acta Neuropathol. 2024 Oct 18;148(1):55. doi: 10.1007/s00401-024-02815-w.
Acta Neuropathol. 2024.
PMID: 39424714
Free PMC article.
Alzheimer's disease (AD) is the leading cause of dementia worldwide. Besides neurofibrillary tangles and amyloid beta (Abeta) plaques, a wide range of co-morbid neuropathological features can be observed in AD brains. ...These findings were conf …
Alzheimer's disease (AD) is the leading cause of dementia worldwide. Besides neurofibrillary tangles and amyloid beta ( …
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