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1962 1
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1976 31
1977 22
1978 30
1979 36
1980 38
1981 53
1982 55
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1984 78
1985 85
1986 107
1987 149
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1989 228
1990 258
1991 318
1992 408
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2000 1064
2001 1107
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2003 1161
2004 1271
2005 1451
2006 1545
2007 1644
2008 1749
2009 1946
2010 2213
2011 2549
2012 2733
2013 2878
2014 3058
2015 3210
2016 3297
2017 3494
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2025 2218

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65,433 results

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Page 1
A genomic compendium of cultivated human gut fungi characterizes the gut mycobiome and its relevance to common diseases.
Yan Q, Li S, Yan Q, Huo X, Wang C, Wang X, Sun Y, Zhao W, Yu Z, Zhang Y, Guo R, Lv Q, He X, Yao C, Li Z, Chen F, Ji Q, Zhang A, Jin H, Wang G, Feng X, Feng L, Wu F, Ning J, Deng S, An Y, Guo DA, Martin FM, Ma X. Yan Q, et al. Cell. 2024 Jun 6;187(12):2969-2989.e24. doi: 10.1016/j.cell.2024.04.043. Epub 2024 May 21. Cell. 2024. PMID: 38776919 Free article.
The gut fungal community represents an essential element of human health, yet its functional and metabolic potential remains insufficiently elucidated, largely due to the limited availability of reference genomes. To address this gap, we presented the cultivated gut fungi …
The gut fungal community represents an essential element of human health, yet its functional and metabolic potential remains insufficiently …
Genomic analysis of inherited hearing loss in the Palestinian population.
Abu Rayyan A, Kamal L, Casadei S, Brownstein Z, Zahdeh F, Shahin H, Canavati C, Dweik D, Jaraysa T, Rabie G, Carlson RJ, Gulsuner S, Lee MK, Avraham KB, Walsh T, King MC, Kanaan MN. Abu Rayyan A, et al. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20070-20076. doi: 10.1073/pnas.2009628117. Epub 2020 Aug 3. Proc Natl Acad Sci U S A. 2020. PMID: 32747562 Free PMC article.
The genetic characterization of a common phenotype for an entire population reveals both the causes of that phenotype for that place and the power of family-based, population-wide genomic analysis for gene and mutation discovery. We characterized the genetics …
The genetic characterization of a common phenotype for an entire population reveals both the causes of that phenotype for that place …
Genomic map of candidate human imprint control regions: the imprintome.
Jima DD, Skaar DA, Planchart A, Motsinger-Reif A, Cevik SE, Park SS, Cowley M, Wright F, House J, Liu A, Jirtle RL, Hoyo C. Jima DD, et al. Epigenetics. 2022 Dec;17(13):1920-1943. doi: 10.1080/15592294.2022.2091815. Epub 2022 Jul 4. Epigenetics. 2022. PMID: 35786392 Free PMC article.
Thus, they are attractive for investigating the developmental origins of adult diseases using accessible tissues, but remain unknown. We determined genome-wide candidate ICRs in humans by performing whole-genome bisulphite sequencing (WGBS) of DNA derived from the t …
Thus, they are attractive for investigating the developmental origins of adult diseases using accessible tissues, but remain unknown. We det …
A new genomic blueprint of the human gut microbiota.
Almeida A, Mitchell AL, Boland M, Forster SC, Gloor GB, Tarkowska A, Lawley TD, Finn RD. Almeida A, et al. Nature. 2019 Apr;568(7753):499-504. doi: 10.1038/s41586-019-0965-1. Epub 2019 Feb 11. Nature. 2019. PMID: 30745586 Free PMC article.
Here we identify 1,952 uncultured candidate bacterial species by reconstructing 92,143 metagenome-assembled genomes from 11,850 human gut microbiomes. These uncultured genomes substantially expand the known species repertoire of the collective human gut microbiota, …
Here we identify 1,952 uncultured candidate bacterial species by reconstructing 92,143 metagenome-assembled genomes from 11,850 human …
The emerging clinical relevance of genomics in cancer medicine.
Berger MF, Mardis ER. Berger MF, et al. Nat Rev Clin Oncol. 2018 Jun;15(6):353-365. doi: 10.1038/s41571-018-0002-6. Nat Rev Clin Oncol. 2018. PMID: 29599476 Free PMC article. Review.
Emerging clinical applications of cancer genomics include monitoring treatment responses and characterizing mechanisms of resistance. The increasing relevance of genomics to clinical cancer care also highlights several considerable challenges, including the n …
Emerging clinical applications of cancer genomics include monitoring treatment responses and characterizing mechanisms of resi …
KEGG: new perspectives on genomes, pathways, diseases and drugs.
Kanehisa M, Furumichi M, Tanabe M, Sato Y, Morishima K. Kanehisa M, et al. Nucleic Acids Res. 2017 Jan 4;45(D1):D353-D361. doi: 10.1093/nar/gkw1092. Epub 2016 Nov 28. Nucleic Acids Res. 2017. PMID: 27899662 Free PMC article.
KEGG (http://www.kegg.jp/ or http://www.genome.jp/kegg/) is an encyclopedia of genes and genomes. Assigning functional meanings to genes and genomes both at the molecular and higher levels is the primary objective of the KEGG database project. ...The newly in …
KEGG (http://www.kegg.jp/ or http://www.genome.jp/kegg/) is an encyclopedia of genes and genomes. Assigning functional meaning …
A unified catalog of 204,938 reference genomes from the human gut microbiome.
Almeida A, Nayfach S, Boland M, Strozzi F, Beracochea M, Shi ZJ, Pollard KS, Sakharova E, Parks DH, Hugenholtz P, Segata N, Kyrpides NC, Finn RD. Almeida A, et al. Nat Biotechnol. 2021 Jan;39(1):105-114. doi: 10.1038/s41587-020-0603-3. Epub 2020 Jul 20. Nat Biotechnol. 2021. PMID: 32690973 Free PMC article.
Comprehensive, high-quality reference genomes are required for functional characterization and taxonomic assignment of the human gut microbiota. We present the Unified Human Gastrointestinal Genome (UHGG) collection, comprising 204,938 nonredundant genomes …
Comprehensive, high-quality reference genomes are required for functional characterization and taxonomic assignment of the hum …
Generation, genomic characterization, and differentiation of triploid human embryonic stem cells.
Haim-Abadi G, Golan-Lev T, Koren A, Benvenisty N. Haim-Abadi G, et al. Stem Cell Reports. 2023 May 9;18(5):1049-1060. doi: 10.1016/j.stemcr.2023.04.001. Epub 2023 Apr 27. Stem Cell Reports. 2023. PMID: 37116485 Free PMC article.
Comparison of the transcriptome, methylome, and genome-wide replication timing shows general similarity between diploid and triploid hESCs. ...
Comparison of the transcriptome, methylome, and genome-wide replication timing shows general similarity between diploid and triploid …
Effect of reduced genomic representation on using runs of homozygosity for inbreeding characterization.
Lavanchy E, Goudet J. Lavanchy E, et al. Mol Ecol Resour. 2023 May;23(4):787-802. doi: 10.1111/1755-0998.13755. Epub 2023 Jan 27. Mol Ecol Resour. 2023. PMID: 36626297
Genomic measures of inbreeding based on identical-by-descent (IBD) segments are increasingly used to measure inbreeding and mostly estimated on SNP arrays and whole-genome sequencing (WGS) data. However, some softwares recurrently used for their estimation assume th …
Genomic measures of inbreeding based on identical-by-descent (IBD) segments are increasingly used to measure inbreeding and mostly es …
Characterization and comparative genomic analysis of novel lytic bacteriophages targeting Cronobacter sakazakii.
Zhang YS, Yuan L, Mgomi FC, Chen CW, Wang Y, Yang ZQ, Jiao XA. Zhang YS, et al. Virus Res. 2023 May;329:199102. doi: 10.1016/j.virusres.2023.199102. Epub 2023 Apr 1. Virus Res. 2023. PMID: 36963724 Free PMC article.
In the current study, four virulent phages that can infect C. sakazakii were isolated from sewage samples, and their biological and complete genomic characteristics were analyzed. A comparative genomic analysis was performed to investigate the functional genes and p …
In the current study, four virulent phages that can infect C. sakazakii were isolated from sewage samples, and their biological and complete …
65,433 results
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