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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1991 1
1993 1
1994 1
1995 1
1996 2
1997 2
1999 1
2000 385
2001 1
2002 2
2003 1
2004 7
2005 5
2006 4
2007 4
2008 14
2009 31
2010 77
2011 104
2012 156
2013 191
2014 287
2015 478
2016 661
2017 894
2018 1047
2019 1230
2020 1453
2021 1789
2022 769
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8,253 results
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Page 1
Review of precision cancer medicine: Evolution of the treatment paradigm.
Tsimberidou AM, Fountzilas E, Nikanjam M, Kurzrock R. Tsimberidou AM, et al. Cancer Treat Rev. 2020 Jun;86:102019. doi: 10.1016/j.ctrv.2020.102019. Epub 2020 Mar 31. Cancer Treat Rev. 2020. PMID: 32251926 Free PMC article. Review.
To improve the implementation of precision medicine, this approach should be used early in the course of the disease, and patients should have complete tumor profiling and access to effective matched therapy. ...In this review, we summarize the clinical trials and d …
To improve the implementation of precision medicine, this approach should be used early in the course of the disease, and pati …
Personalized In Vitro and In Vivo Cancer Models to Guide Precision Medicine.
Pauli C, Hopkins BD, Prandi D, Shaw R, Fedrizzi T, Sboner A, Sailer V, Augello M, Puca L, Rosati R, McNary TJ, Churakova Y, Cheung C, Triscott J, Pisapia D, Rao R, Mosquera JM, Robinson B, Faltas BM, Emerling BE, Gadi VK, Bernard B, Elemento O, Beltran H, Demichelis F, Kemp CJ, Grandori C, Cantley LC, Rubin MA. Pauli C, et al. Cancer Discov. 2017 May;7(5):462-477. doi: 10.1158/2159-8290.CD-16-1154. Epub 2017 Mar 22. Cancer Discov. 2017. PMID: 28331002 Free PMC article.
Precision medicine is an approach that takes into account the influence of individuals' genes, environment, and lifestyle exposures to tailor interventions. ...This platform thereby promotes the discovery of novel therapeutic approaches that can be assessed in clini …
Precision medicine is an approach that takes into account the influence of individuals' genes, environment, and lifestyle expo …
Enabling Technologies for Personalized and Precision Medicine.
Ho D, Quake SR, McCabe ERB, Chng WJ, Chow EK, Ding X, Gelb BD, Ginsburg GS, Hassenstab J, Ho CM, Mobley WC, Nolan GP, Rosen ST, Tan P, Yen Y, Zarrinpar A. Ho D, et al. Trends Biotechnol. 2020 May;38(5):497-518. doi: 10.1016/j.tibtech.2019.12.021. Epub 2020 Jan 21. Trends Biotechnol. 2020. PMID: 31980301 Free PMC article. Review.
This work highlights key breakthroughs in the development of enabling technologies that further the goal of personalized and precision medicine, and remaining challenges that, when addressed, may forge unprecedented capabilities in realizing truly individuali …
This work highlights key breakthroughs in the development of enabling technologies that further the goal of personalized and preci …
Next Generation Sequencing (NGS): A Revolutionary Technology in Pharmacogenomics and Personalized Medicine in Cancer.
Morganti S, Tarantino P, Ferraro E, D'Amico P, Duso BA, Curigliano G. Morganti S, et al. Adv Exp Med Biol. 2019;1168:9-30. doi: 10.1007/978-3-030-24100-1_2. Adv Exp Med Biol. 2019. PMID: 31713162 Review.
The development of next-generation-sequencing (NGS) techniques, commercially available since 2006, allowed for a cost- and time-effective sequencing of tumor DNA, leading to a "genomic era" of cancer research and treatment. NGS provided a significant step forward in Per …
The development of next-generation-sequencing (NGS) techniques, commercially available since 2006, allowed for a cost- and time-effective se …
Precision Medicine: From Science To Value.
Ginsburg GS, Phillips KA. Ginsburg GS, et al. Health Aff (Millwood). 2018 May;37(5):694-701. doi: 10.1377/hlthaff.2017.1624. Health Aff (Millwood). 2018. PMID: 29733705 Free PMC article. Review.
Precision medicine is making an impact on patients, health care delivery systems, and research participants in ways that were only imagined fifteen years ago when the human genome was first sequenced. Discovery of disease-causing and drug-response genetic variants h …
Precision medicine is making an impact on patients, health care delivery systems, and research participants in ways that were …
Genomic Medicine-Progress, Pitfalls, and Promise.
Shendure J, Findlay GM, Snyder MW. Shendure J, et al. Cell. 2019 Mar 21;177(1):45-57. doi: 10.1016/j.cell.2019.02.003. Cell. 2019. PMID: 30901547 Free PMC article. Review.
In the wake of the Human Genome Project (HGP), strong expectations were set for the timeline and impact of genomics on medicine-an anticipated transformation in the diagnosis, treatment, and prevention of disease. In this Perspective, we take stock of the nascent field of …
In the wake of the Human Genome Project (HGP), strong expectations were set for the timeline and impact of genomics on medicine-an an …
Current Perspectives on Circulating Tumor DNA, Precision Medicine, and Personalized Clinical Management of Cancer.
Oliveira KCS, Ramos IB, Silva JMC, Barra WF, Riggins GJ, Palande V, Pinho CT, Frenkel-Morgenstern M, Santos SEB, Assumpcao PP, Burbano RR, Calcagno DQ. Oliveira KCS, et al. Mol Cancer Res. 2020 Apr;18(4):517-528. doi: 10.1158/1541-7786.MCR-19-0768. Epub 2020 Jan 29. Mol Cancer Res. 2020. PMID: 31996469 Review.
Circulating tumor DNA (ctDNA) has recently emerged as a minimally invasive "liquid biopsy" tool in precision medicine. ctDNA-genomic DNA fragments that are released into the bloodstream after the active secretion of microvesicles or tumor cell lysis reflects …
Circulating tumor DNA (ctDNA) has recently emerged as a minimally invasive "liquid biopsy" tool in precision medicine. ctDNA- …
Breast cancer: The translation of big genomic data to cancer precision medicine.
Low SK, Zembutsu H, Nakamura Y. Low SK, et al. Cancer Sci. 2018 Mar;109(3):497-506. doi: 10.1111/cas.13463. Epub 2017 Dec 30. Cancer Sci. 2018. PMID: 29215763 Free PMC article. Review.
For the past 2 decades, genomic research has advanced remarkably, evolving from single-gene to whole-genome screening by using genome-wide association study and next-generation sequencing that contributes to big genomic data. ...Focusing on breast cancer, the presen …
For the past 2 decades, genomic research has advanced remarkably, evolving from single-gene to whole-genome screening by using genome …
Precision medicine and therapies of the future.
Sisodiya SM. Sisodiya SM. Epilepsia. 2021 Mar;62 Suppl 2(Suppl 2):S90-S105. doi: 10.1111/epi.16539. Epub 2020 Jul 24. Epilepsia. 2021. PMID: 32776321 Free PMC article. Review.
Precision medicine in the epilepsies has gathered much attention, especially with gene discovery pushing forward new understanding of disease biology. ...Failures of precision medicine may not find their way to broader scrutiny. Precision med …
Precision medicine in the epilepsies has gathered much attention, especially with gene discovery pushing forward new understan …
Precision medicine in diabetes prevention, classification and management.
Xie F, Chan JC, Ma RC. Xie F, et al. J Diabetes Investig. 2018 Sep;9(5):998-1015. doi: 10.1111/jdi.12830. Epub 2018 Apr 25. J Diabetes Investig. 2018. PMID: 29499103 Free PMC article. Review.
Diabetes management following a uniform treatment algorithm is often associated with progressive treatment failure and development of diabetic complications. Recent advances in our understanding of the genomic architecture of diabetes and its complications have provided th …
Diabetes management following a uniform treatment algorithm is often associated with progressive treatment failure and development of diabet …
8,253 results