Genomic medicine, precision medicine, personalized medicine: what's in a name?
Clin Pharmacol Ther. 2013.
PMID: 23872826
Free PMC article.
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found by citation matching
From "Personalized" to "Precision" Medicine: The Ethical and Social Implications of Rhetorical Reform in Genomic Medicine.
Hastings Cent Rep. 2016.
PMID: 27649826
Free PMC article.
From genomes to genomic medicine: enabling personalized and precision medicine in the Middle East.
Per Med. 2017.
PMID: 29754564
No abstract available.
Search results
Page 1
Review of precision cancer medicine: Evolution of the treatment paradigm.
Cancer Treat Rev. 2020 Jun;86:102019. doi: 10.1016/j.ctrv.2020.102019. Epub 2020 Mar 31.
Cancer Treat Rev. 2020.
PMID: 32251926
Free PMC article.
Review.
To improve the implementation of precision medicine, this approach should be used early in the course of the disease, and patients should have complete tumor profiling and access to effective matched therapy. ...In this review, we summarize the clinical trials and d …
To improve the implementation of precision medicine, this approach should be used early in the course of the disease, and pati …
Precision medicine and therapies of the future.
Epilepsia. 2021 Mar;62 Suppl 2(Suppl 2):S90-S105. doi: 10.1111/epi.16539. Epub 2020 Jul 24.
Epilepsia. 2021.
PMID: 32776321
Free PMC article.
Review.
Precision medicine in the epilepsies has gathered much attention, especially with gene discovery pushing forward new understanding of disease biology. ...Failures of precision medicine may not find their way to broader scrutiny. Precision med …
Precision medicine in the epilepsies has gathered much attention, especially with gene discovery pushing forward new understan …
Enabling Technologies for Personalized and Precision Medicine.
Trends Biotechnol. 2020 May;38(5):497-518. doi: 10.1016/j.tibtech.2019.12.021. Epub 2020 Jan 21.
Trends Biotechnol. 2020.
PMID: 31980301
Free PMC article.
Review.
This work highlights key breakthroughs in the development of enabling technologies that further the goal of personalized and precision medicine, and remaining challenges that, when addressed, may forge unprecedented capabilities in realizing truly individuali …
This work highlights key breakthroughs in the development of enabling technologies that further the goal of personalized and preci …
Precision Medicine, AI, and the Future of Personalized Health Care.
Clin Transl Sci. 2021 Jan;14(1):86-93. doi: 10.1111/cts.12884. Epub 2020 Oct 12.
Clin Transl Sci. 2021.
PMID: 32961010
Free PMC article.
Review.
The convergence of artificial intelligence (AI) and precision medicine promises to revolutionize health care. Precision medicine methods identify phenotypes of patients with less-common responses to treatment or unique healthcare needs. ...Recent liter …
The convergence of artificial intelligence (AI) and precision medicine promises to revolutionize health care. Precision …
Next Generation Sequencing (NGS): A Revolutionary Technology in Pharmacogenomics and Personalized Medicine in Cancer.
Adv Exp Med Biol. 2019;1168:9-30. doi: 10.1007/978-3-030-24100-1_2.
Adv Exp Med Biol. 2019.
PMID: 31713162
Review.
The development of next-generation-sequencing (NGS) techniques, commercially available since 2006, allowed for a cost- and time-effective sequencing of tumor DNA, leading to a "genomic era" of cancer research and treatment. NGS provided a significant step forward in Per …
The development of next-generation-sequencing (NGS) techniques, commercially available since 2006, allowed for a cost- and time-effective se …
Next-generation cancer organoids.
Nat Mater. 2022 Feb;21(2):143-159. doi: 10.1038/s41563-021-01057-5. Epub 2021 Aug 12.
Nat Mater. 2022.
PMID: 34385685
Review.
Organotypic models of patient-specific tumours are revolutionizing our understanding of cancer heterogeneity and its implications for personalized medicine. These advancements are, in part, attributed to the ability of organoid models to stably preserve genetic, pro …
Organotypic models of patient-specific tumours are revolutionizing our understanding of cancer heterogeneity and its implications for per …
Genomic Medicine-Progress, Pitfalls, and Promise.
Cell. 2019 Mar 21;177(1):45-57. doi: 10.1016/j.cell.2019.02.003.
Cell. 2019.
PMID: 30901547
Free PMC article.
Review.
In the wake of the Human Genome Project (HGP), strong expectations were set for the timeline and impact of genomics on medicine-an anticipated transformation in the diagnosis, treatment, and prevention of disease. In this Perspective, we take stock of the nascent field of …
In the wake of the Human Genome Project (HGP), strong expectations were set for the timeline and impact of genomics on medicine-an an …
Precision Medicine: From Science To Value.
Health Aff (Millwood). 2018 May;37(5):694-701. doi: 10.1377/hlthaff.2017.1624.
Health Aff (Millwood). 2018.
PMID: 29733705
Free PMC article.
Review.
Precision medicine is making an impact on patients, health care delivery systems, and research participants in ways that were only imagined fifteen years ago when the human genome was first sequenced. Discovery of disease-causing and drug-response genetic variants h …
Precision medicine is making an impact on patients, health care delivery systems, and research participants in ways that were …
Tumor organoids: applications in cancer modeling and potentials in precision medicine.
J Hematol Oncol. 2022 May 12;15(1):58. doi: 10.1186/s13045-022-01278-4.
J Hematol Oncol. 2022.
PMID: 35551634
Free PMC article.
Review.
These factors contribute to treatment failure and an unfavorable prognosis. Personalized tumor models faithfully capturing the tumor heterogeneity of individual patients are urgently needed for precision medicine. Advances in stem cell culture have given rise …
These factors contribute to treatment failure and an unfavorable prognosis. Personalized tumor models faithfully capturing the tumor …
Clinical trial design in the era of precision medicine.
Genome Med. 2022 Aug 31;14(1):101. doi: 10.1186/s13073-022-01102-1.
Genome Med. 2022.
PMID: 36045401
Free PMC article.
Review.
Recent rapid biotechnological breakthroughs have led to the identification of complex and unique molecular features that drive malignancies. Precision medicine has exploited next-generation sequencing and matched targeted therapy/immunotherapy deployment to successf …
Recent rapid biotechnological breakthroughs have led to the identification of complex and unique molecular features that drive malignancies. …
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