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Prion inhibition with multivalent PrPSc binding compounds.
Mays CE, Joy S, Li L, Yu L, Genovesi S, West FG, Westaway D. Mays CE, et al. Among authors: genovesi s. Biomaterials. 2012 Oct;33(28):6808-22. doi: 10.1016/j.biomaterials.2012.06.004. Epub 2012 Jun 28. Biomaterials. 2012. PMID: 22748770
Wild-type Shadoo proteins convert to amyloid-like forms under native conditions.
Daude N, Ng V, Watts JC, Genovesi S, Glaves JP, Wohlgemuth S, Schmitt-Ulms G, Young H, McLaurin J, Fraser PE, Westaway D. Daude N, et al. Among authors: genovesi s. J Neurochem. 2010 Apr;113(1):92-104. doi: 10.1111/j.1471-4159.2010.06575.x. Epub 2010 Jan 8. J Neurochem. 2010. PMID: 20067571 Free article.
Down-regulation of Shadoo in prion infections traces a pre-clinical event inversely related to PrP(Sc) accumulation.
Westaway D, Genovesi S, Daude N, Brown R, Lau A, Lee I, Mays CE, Coomaraswamy J, Canine B, Pitstick R, Herbst A, Yang J, Ko KW, Schmitt-Ulms G, Dearmond SJ, McKenzie D, Hood L, Carlson GA. Westaway D, et al. Among authors: genovesi s. PLoS Pathog. 2011 Nov;7(11):e1002391. doi: 10.1371/journal.ppat.1002391. Epub 2011 Nov 17. PLoS Pathog. 2011. PMID: 22114562 Free PMC article.
RGG repeats of PrP-like Shadoo protein bind nucleic acids.
Lau A, Mays CE, Genovesi S, Westaway D. Lau A, et al. Among authors: genovesi s. Biochemistry. 2012 Nov 13;51(45):9029-31. doi: 10.1021/bi301395w. Epub 2012 Nov 2. Biochemistry. 2012. PMID: 23121093
Direct detection of soil-bound prions.
Genovesi S, Leita L, Sequi P, Andrighetto I, Sorgato MC, Bertoli A. Genovesi S, et al. PLoS One. 2007 Oct 24;2(10):e1069. doi: 10.1371/journal.pone.0001069. PLoS One. 2007. PMID: 17957252 Free PMC article.
Loss of GABAergic neurons in the hippocampus and cerebral cortex of Engrailed-2 null mutant mice: implications for autism spectrum disorders.
Sgadò P, Genovesi S, Kalinovsky A, Zunino G, Macchi F, Allegra M, Murenu E, Provenzano G, Tripathi PP, Casarosa S, Joyner AL, Bozzi Y. Sgadò P, et al. Among authors: genovesi s. Exp Neurol. 2013 Sep;247:496-505. doi: 10.1016/j.expneurol.2013.01.021. Epub 2013 Jan 27. Exp Neurol. 2013. PMID: 23360806 Free PMC article.
177 results