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Kinetic analysis of estrogen receptor/ligand interactions.
Rich RL, Hoth LR, Geoghegan KF, Brown TA, LeMotte PK, Simons SP, Hensley P, Myszka DG. Rich RL, et al. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8562-7. doi: 10.1073/pnas.142288199. Epub 2002 Jun 19. Proc Natl Acad Sci U S A. 2002. PMID: 12077320 Free PMC article.
Discovery of a Selective Covalent Inhibitor of Lysophospholipase-like 1 (LYPLAL1) as a Tool to Evaluate the Role of this Serine Hydrolase in Metabolism.
Ahn K, Boehm M, Brown MF, Calloway J, Che Y, Chen J, Fennell KF, Geoghegan KF, Gilbert AM, Gutierrez JA, Kalgutkar AS, Lanba A, Limberakis C, Magee TV, O'Doherty I, Oliver R, Pabst B, Pandit J, Parris K, Pfefferkorn JA, Rolph TP, Patel R, Schuff B, Shanmugasundaram V, Starr JT, Varghese AH, Vera NB, Vernochet C, Yan J. Ahn K, et al. ACS Chem Biol. 2016 Sep 16;11(9):2529-40. doi: 10.1021/acschembio.6b00266. Epub 2016 Jul 19. ACS Chem Biol. 2016. PMID: 27391855
Dominance of amyloid precursor protein sequence over host cell secretases in determining beta-amyloid profiles studies of interspecies variation and drug action by internally standardized immunoprecipitation/mass spectrometry.
Du P, Wood KM, Rosner MH, Cunningham D, Tate B, Geoghegan KF. Du P, et al. J Pharmacol Exp Ther. 2007 Mar;320(3):1144-52. doi: 10.1124/jpet.106.114561. Epub 2007 Jan 3. J Pharmacol Exp Ther. 2007. PMID: 17202404
Synthesis and biological activity of selective pipecolic acid-based TNF-alpha converting enzyme (TACE) inhibitors.
Letavic MA, Axt MZ, Barberia JT, Carty TJ, Danley DE, Geoghegan KF, Halim NS, Hoth LR, Kamath AV, Laird ER, Lopresti-Morrow LL, McClure KF, Mitchell PG, Natarajan V, Noe MC, Pandit J, Reeves L, Schulte GK, Snow SL, Sweeney FJ, Tan DH, Yu CH. Letavic MA, et al. Bioorg Med Chem Lett. 2002 May 20;12(10):1387-90. doi: 10.1016/s0960-894x(02)00183-x. Bioorg Med Chem Lett. 2002. PMID: 11992783
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