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BRCA1 involvement in toxicological responses and human cancer etiology.
Georgakilas AG, Aziz K, Ziech D, Georgakila S, Panayiotidis MI. Georgakilas AG, et al. Toxicol Lett. 2009 Jul 24;188(2):77-83. doi: 10.1016/j.toxlet.2009.04.006. Epub 2009 Apr 16. Toxicol Lett. 2009. PMID: 19375487 Review.
Induction and repair of clustered DNA lesions: what do we know so far?
Georgakilas AG, O'Neill P, Stewart RD. Georgakilas AG, et al. Radiat Res. 2013 Jul;180(1):100-9. doi: 10.1667/RR3041.1. Epub 2013 May 17. Radiat Res. 2013. PMID: 23682596 Review.
DNA-PKcs deficiency leads to persistence of oxidatively induced clustered DNA lesions in human tumor cells.
Peddi P, Loftin CW, Dickey JS, Hair JM, Burns KJ, Aziz K, Francisco DC, Panayiotidis MI, Sedelnikova OA, Bonner WM, Winters TA, Georgakilas AG. Peddi P, et al. Free Radic Biol Med. 2010 May 15;48(10):1435-43. doi: 10.1016/j.freeradbiomed.2010.02.033. Epub 2010 Mar 1. Free Radic Biol Med. 2010. PMID: 20193758 Free PMC article.
Measurement of oxidatively-induced clustered DNA lesions using a novel adaptation of single cell gel electrophoresis (comet assay).
Georgakilas AG, Holt SM, Hair JM, Loftin CW. Georgakilas AG, et al. Curr Protoc Cell Biol. 2010 Dec;Chapter 6:Unit 6.11.. doi: 10.1002/0471143030.cb0611s49. Curr Protoc Cell Biol. 2010. PMID: 21154553
Systemic DNA damage accumulation under in vivo tumor growth can be inhibited by the antioxidant Tempol.
Georgakilas AG, Redon CE, Ferguson NF, Kryston TB, Parekh P, Dickey JS, Nakamura AJ, Mitchell JB, Bonner WM, Martin OA. Georgakilas AG, et al. Cancer Lett. 2014 Oct 28;353(2):248-57. doi: 10.1016/j.canlet.2014.07.030. Epub 2014 Jul 25. Cancer Lett. 2014. PMID: 25069035 Free PMC article.
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