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Surface-active compounds from microorganisms.
Georgiou G, Lin SC, Sharma MM. Georgiou G, et al. Biotechnology (N Y). 1992 Jan;10(1):60-5. doi: 10.1038/nbt0192-60. Biotechnology (N Y). 1992. PMID: 1368190 Review.
Function-based isolation of novel enzymes from a large library.
Olsen MJ, Stephens D, Griffiths D, Daugherty P, Georgiou G, Iverson BL. Olsen MJ, et al. Nat Biotechnol. 2000 Oct;18(10):1071-4. doi: 10.1038/80267. Nat Biotechnol. 2000. PMID: 11017045
Simple genetic selection protocol for isolation of overexpressed genes that enhance accumulation of membrane-integrated human G protein-coupled receptors in Escherichia coli.
Skretas G, Georgiou G. Skretas G, et al. Appl Environ Microbiol. 2010 Sep;76(17):5852-9. doi: 10.1128/AEM.00963-10. Epub 2010 Jul 16. Appl Environ Microbiol. 2010. PMID: 20639362 Free PMC article.
Notably, coexpression of ybaB, a gene encoding a putative DNA-binding protein of unknown function, was found to enhance the accumulation of a variety of membrane-integrated human G protein-coupled receptors and other integral membrane proteins in E. coli by up to 10-fold. …
Notably, coexpression of ybaB, a gene encoding a putative DNA-binding protein of unknown function, was found to enhance the accumulation of …
Beyond toothpicks: new methods for isolating mutant bacteria.
Link AJ, Jeong KJ, Georgiou G. Link AJ, et al. Nat Rev Microbiol. 2007 Sep;5(9):680-8. doi: 10.1038/nrmicro1715. Nat Rev Microbiol. 2007. PMID: 17676054 Review.
Developmental pathway for potent V1V2-directed HIV-neutralizing antibodies.
Doria-Rose NA, Schramm CA, Gorman J, Moore PL, Bhiman JN, DeKosky BJ, Ernandes MJ, Georgiev IS, Kim HJ, Pancera M, Staupe RP, Altae-Tran HR, Bailer RT, Crooks ET, Cupo A, Druz A, Garrett NJ, Hoi KH, Kong R, Louder MK, Longo NS, McKee K, Nonyane M, O'Dell S, Roark RS, Rudicell RS, Schmidt SD, Sheward DJ, Soto C, Wibmer CK, Yang Y, Zhang Z; NISC Comparative Sequencing Program, Mullikin JC, Binley JM, Sanders RW, Wilson IA, Moore JP, Ward AB, Georgiou G, Williamson C, Abdool Karim SS, Morris L, Kwong PD, Shapiro L, Mascola JR. Doria-Rose NA, et al. Nature. 2014 May 1;509(7498):55-62. doi: 10.1038/nature13036. Epub 2014 Mar 2. Nature. 2014. PMID: 24590074 Free PMC article.
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