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Protease-activated receptor 2 sensitizes the transient receptor potential vanilloid 4 ion channel to cause mechanical hyperalgesia in mice.
Grant AD, Cottrell GS, Amadesi S, Trevisani M, Nicoletti P, Materazzi S, Altier C, Cenac N, Zamponi GW, Bautista-Cruz F, Lopez CB, Joseph EK, Levine JD, Liedtke W, Vanner S, Vergnolle N, Geppetti P, Bunnett NW. Grant AD, et al. Among authors: geppetti p. J Physiol. 2007 Feb 1;578(Pt 3):715-33. doi: 10.1113/jphysiol.2006.121111. Epub 2006 Nov 23. J Physiol. 2007. PMID: 17124270 Free PMC article.
The TGR5 receptor mediates bile acid-induced itch and analgesia.
Alemi F, Kwon E, Poole DP, Lieu T, Lyo V, Cattaruzza F, Cevikbas F, Steinhoff M, Nassini R, Materazzi S, Guerrero-Alba R, Valdez-Morales E, Cottrell GS, Schoonjans K, Geppetti P, Vanner SJ, Bunnett NW, Corvera CU. Alemi F, et al. Among authors: geppetti p. J Clin Invest. 2013 Apr;123(4):1513-30. doi: 10.1172/JCI64551. Epub 2013 Mar 25. J Clin Invest. 2013. PMID: 23524965 Free PMC article.
413 results