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The C5a chemoattractant receptor mediates mucosal defence to infection.
Höpken UE, Lu B, Gerard NP, Gerard C. Höpken UE, et al. Nature. 1996 Sep 5;383(6595):86-9. doi: 10.1038/383086a0. Nature. 1996. PMID: 8779720
The role of N-glycosylation for functional expression of the human platelet-activating factor receptor. Glycosylation is required for efficient membrane trafficking.
García Rodríguez C, Cundell DR, Tuomanen EI, Kolakowski LF Jr, Gerard C, Gerard NP. García Rodríguez C, et al. J Biol Chem. 1995 Oct 20;270(42):25178-84. doi: 10.1074/jbc.270.42.25178. J Biol Chem. 1995. PMID: 7559653
., Gerard, N. P., Gerard, C., Idanpaan-Heikkila, I., and Tuomanen, E. I. (1995) Nature, in press). Because bacterial binding is in part carbohydrate dependent, and the human platelet-activating factor (PAF) receptor bears a single N-linked glycosylation seque …
., Gerard, N. P., Gerard, C., Idanpaan-Heikkila, I., and Tuomanen, E. I. (1995) Nature, in press). Because bacterial bi …
The chemotactic receptor for human C5a anaphylatoxin.
Gerard NP, Gerard C. Gerard NP, et al. Nature. 1991 Feb 14;349(6310):614-7. doi: 10.1038/349614a0. Nature. 1991. PMID: 1847994
CCR3 is a target for age-related macular degeneration diagnosis and therapy.
Takeda A, Baffi JZ, Kleinman ME, Cho WG, Nozaki M, Yamada K, Kaneko H, Albuquerque RJ, Dridi S, Saito K, Raisler BJ, Budd SJ, Geisen P, Munitz A, Ambati BK, Green MG, Ishibashi T, Wright JD, Humbles AA, Gerard CJ, Ogura Y, Pan Y, Smith JR, Grisanti S, Hartnett ME, Rothenberg ME, Ambati J. Takeda A, et al. Nature. 2009 Jul 9;460(7252):225-30. doi: 10.1038/nature08151. Epub 2009 Jun 14. Nature. 2009. PMID: 19525930 Free PMC article.
PAf receptor anchors Streptococcus pneumoniae to activated human endothelial cells.
Cundell DR, Gerard C, Idanpaan-Heikkila I, Tuomanen EI, Gerard NP. Cundell DR, et al. Adv Exp Med Biol. 1996;416:89-94. doi: 10.1007/978-1-4899-0179-8_16. Adv Exp Med Biol. 1996. PMID: 9131132 Review.
Receptor-dependent internalization of platelet-activating factor.
Gerard NP, Gerard C. Gerard NP, et al. J Immunol. 1994 Jan 15;152(2):793-800. J Immunol. 1994. PMID: 8283052
The ligand-receptor interaction is markedly temperature dependent, with approximately 10-fold more [3H]PAF specifically associated with the cells at 37 degrees C than at 4 degrees C. ...In the absence of transfected receptor no specific binding is detected in COS-7 …
The ligand-receptor interaction is markedly temperature dependent, with approximately 10-fold more [3H]PAF specifically associated with the …
Bacterial infection. For whom the bell tolls.
Gerard C. Gerard C. Nature. 1998 Sep 17;395(6699):217, 219. doi: 10.1038/26104. Nature. 1998. PMID: 9751041 No abstract available.
A role for the C3a anaphylatoxin receptor in the effector phase of asthma.
Humbles AA, Lu B, Nilsson CA, Lilly C, Israel E, Fujiwara Y, Gerard NP, Gerard C. Humbles AA, et al. Nature. 2000 Aug 31;406(6799):998-1001. doi: 10.1038/35023175. Nature. 2000. PMID: 10984054 Clinical Trial.
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